World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
17722
World Ranking
15917
National Ranking
6613

Overview

Jeffrey T. Chang is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research spans fields predominantly in Biochemistry, Genetics and Molecular Biology, with a significant focus also on Medicine. Within these domains, the main subfields of study include Molecular Biology, Oncology, Cancer Research, Surgery, and Immunology.

The scientist's work covers multiple topics related to cancer research, specifically:

  • Cancer Genomics and Diagnostics
  • Cancer Cells and Metastasis
  • Cancer Immunotherapy and Biomarkers
  • Single-cell and spatial transcriptomics
  • RNA modifications and cancer
  • Advanced Breast Cancer Therapies
  • Breast Cancer Treatment Studies

Jeffrey T. Chang has published extensively in various scientific venues. The most frequent publication outlets include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Clinical Cancer Research
  • npj Breast Cancer

Notable recent papers authored by or involving Jeffrey T. Chang include:

  • "EMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures," 2020, British Journal of Cancer
  • "Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages," 2020, Soft Matter
  • "Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy," 2020, Proceedings of the National Academy of Sciences
  • "Human NOP2/NSUN1 regulates ribosome biogenesis through non-catalytic complex formation with box C/D snoRNPs," 2022, Nucleic Acids Research
  • "Torsional Diffusion for Molecular Conformer Generation," 2022, arXiv (Cornell University)

Frequent collaborators in their research network include:

  • Andrea H. Bild
  • Patrick A. Cosgrove
  • Helen Piwnica-Worms
  • W. Fraser Symmans
  • Stacy L. Moulder

Best Publications

  • Biopython: freely available Python tools for computational molecular biology and bioinformatics

    Peter J. A. Cock;Tiago Antao;Jeffrey T. Chang;Brad A. Chapman

  • Oncogenic pathway signatures in human cancers as a guide to targeted therapies.

    Andrea H. Bild;Guang Yao;Jeffrey T. Chang;Quanli Wang

  • High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types.

    DJ McGrail;PG Pilié;NU Rashid;L Voorwerk

  • High-dimensional sparse factor modeling: Applications in gene expression genomics

    Carlos Marinho Carvalho;Jeffrey Chang;Joseph E. Lucas;Joseph R. Nevins

  • Integrating genotype and phenotype information: an overview of the PharmGKB project

    T. E. Klein;Jeffrey T Chang;M. K. Cho;K. L. Easton

  • GATHER: a systems approach to interpreting genomic signatures

    Jeffrey T. Chang;Joseph R. Nevins

  • Anchorage-independent cell growth signature identifies tumors with metastatic potential

    Seiichi Mori;Jeffrey T. Chang;Eran R. Andrechek;Noriomi Matsumura;Noriomi Matsumura

  • FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer

    Brett G. Hollier;Agata A. Tinnirello;Steven J. Werden;Kurt W. Evans

  • Creating an online dictionary of abbreviations from MEDLINE.

    Jeffrey T. Chang;Hinrich Schütze;Russ B. Altman

  • Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature.

    Soumya Raychaudhuri;Jeffrey T. Chang;Patrick D. Sutphin;Russ B. Altman

  • Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

    Tuan Zea Tan;Qing Hao Miow;Ruby Yun Ju Huang;Meng Kang Wong

  • Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state

    Gloria V. Echeverria;Zhongqi Ge;Sahil Seth;Xiaomei Zhang

  • Biopython: Python tools for computational biology

    Brad Chapman;Jeffrey Chang

  • Basic microarray analysis: grouping and feature reduction.

    Soumya Raychaudhuri;Patrick D. Sutphin;Jeffrey T. Chang;Russ B. Altman

  • Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

    Qing Cheng;Jeffrey T Chang;Joseph Geradts;Leonard M Neckers

  • A Dynamic Bronchial Airway Gene Expression Signature of Chronic Obstructive Pulmonary Disease and Lung Function Impairment

    Katrina Steiling;Maarten van den Berge;Kahkeshan Hijazi;Roberta Florido

  • EMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures.

    Suhas V. Vasaikar;Abhijeet P. Deshmukh;Petra den Hollander;Sridevi Addanki

  • GAPSCORE: finding gene and protein names one word at a time

    Jeffrey T. Chang;Hinrich Schütze;Russ B. Altman

  • Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity

    Weina Zhao;Sara Prijic;Bettina C. Urban;Michael J. Tisza

  • Abstract GS5-05: Resistance to neoadjuvant chemotherapy in triple negative breast cancer mediated by a reversible drug-tolerant state

    GV Echeverria;Z Ge;S Seth;SL Jeter-Jones

Frequent Co-Authors

Sendurai A. Mani
Sendurai A. Mani Brown University
Joseph R. Nevins
Joseph R. Nevins Duke University
Russ B. Altman
Russ B. Altman Stanford University
Jeffrey M. Rosen
Jeffrey M. Rosen Baylor College of Medicine
Adam L. Cohen
Adam L. Cohen Inova Health System
Timothy P. Heffernan
Timothy P. Heffernan The University of Texas MD Anderson Cancer Center
Ignacio I. Wistuba
Ignacio I. Wistuba The University of Texas MD Anderson Cancer Center
Alastair M. Thompson
Alastair M. Thompson Baylor College of Medicine
Xiang Zhang
Xiang Zhang University of Hong Kong
Michelle Craig Barton
Michelle Craig Barton The University of Texas MD Anderson Cancer Center

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