World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
9226
World Ranking
17186
National Ranking
63

Overview

Tuan Zea Tan is affiliated with the National University of Singapore in Singapore. Their research spans multiple aspects of biochemistry, genetics, molecular biology, and medicine, with a particular focus on oncology and cancer-related molecular mechanisms. The scientist's work intersects key subfields including molecular biology, oncology, cancer research, immunology, and reproductive medicine.

The major research topics covered by their publications include ovarian cancer diagnosis and treatment, cancer cells and metastasis, cancer genomics and diagnostics, cancer-related molecular mechanisms research, cancer immunotherapy and biomarkers, ubiquitin and proteasome pathways, and phagocytosis and immune regulation.

Frequent co-authors in their body of work include:

  • Ruby Yun-Ju Huang
  • David S.P. Tan
  • Jean Paul Thiery
  • Jieru Ye
  • Alan Prem Kumar

The scientist has published extensively in several journals and venues with the most frequent being:

  • Cancer Research
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Communications Biology
  • Annals of Oncology

Selected recent papers include:

  • Epithelial-to-Mesenchymal Transition is a Cause of Both Intrinsic and Acquired Resistance to KRAS G12C Inhibitor in KRAS G12C-Mutant Non-Small Cell Lung Cancer, 2020, Clinical Cancer Research
  • Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis, 2021, Cancers
  • Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective, 2020, Cancers
  • Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity, 2020, EMBO Molecular Medicine
  • AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells, 2020, Journal of Thoracic Oncology

Best Publications

  • Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.

    Tuan Zea Tan;Qing Hao Miow;Yoshio Miki;Tetsuo Noda

  • An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)

    R Y-J Huang;M K Wong;T Z Tan;K T Kuay

  • Dual role of autophagy in hallmarks of cancer.

    Shikha Satendra Singh;Somya Vats;Amelia Yi-Qian Chia;Tuan Zea Tan

  • Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell–Mediated Lysis

    Intissar Akalay;Bassam Janji;Meriem Hasmim;Muhammad Zaeem Noman

  • Molecular Subtypes of Urothelial Bladder Cancer: Results from a Meta-cohort Analysis of 2411 Tumors.

    Tuan Zea Tan;Mathieu Rouanne;Kien Thiam Tan;Ruby Yun-Ju Huang

  • Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

    Tuan Zea Tan;Qing Hao Miow;Ruby Yun Ju Huang;Meng Kang Wong

  • The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200

    Muhammad Zaeem Noman;Bassam Janji;Abderemane Abdou;Meriem Hasmim

  • Lgr5 marks stem/progenitor cells in ovary and tubal epithelia

    Annie Ng;Shawna Tan;Gurmit Singh;Pamela Rizk

  • Molecular characterization of breast cancer CTCs associated with brain metastasis

    Debasish Boral;Monika Vishnoi;Haowen N. Liu;Wei Yin

  • Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy

    Bee Luan Khoo;Soo Chin Lee;Prashant Kumar;Tuan Zea Tan

  • Epithelial-to-Mesenchymal Transition is a Cause of Both Intrinsic and Acquired Resistance to KRAS G12C Inhibitor in KRAS G12C–Mutant Non–Small Cell Lung Cancer

    Yuta Adachi;Kentaro Ito;Yuko Hayashi;Ryo Kimura

  • FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway.

    M Asad;Maggie M. K. Wong;T Z Tan;M Choolani

  • DEAD-box helicase DP103 defines metastatic potential of human breast cancers

    Eun Myoung Shin;Hui Sin Hay;Moon Hee Lee;Jen Nee Goh

  • GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification

    Vin Yee Chung;Tuan Zea Tan;Ming Tan;Meng Kang Wong

  • Epithelial–mesenchymal status renders differential responses to cisplatin in ovarian cancer

    Miow Qh;Tan Tz;Ye J;Lau Ja

  • A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets.

    Dongyu Jia;Zhenqiu Liu;Nan Deng;Tuan Zea Tan

  • TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex.

    Wen Hsin Lee;Lee Yee Choong;Naing Naing Mon;SsuYi Lu

  • Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis.

    Arpita Datta;Shuo Deng;Vennila Gopal;Kenneth Chun-Hong Yap

  • The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype–specific therapeutic target for ovarian cancer

    Jane Antony;Jane Antony;Tuan Zea Tan;Zoe Kelly;Jeffrey Low

  • Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects

    Chelsia Qiuxia Wang;Chelsia Qiuxia Wang;Vaidehi Krishnan;Lavina Sierra Tay;Desmond Wai Loon Chin

Frequent Co-Authors

Jean Paul Thiery
Jean Paul Thiery National University of Singapore
Alan Prem Kumar
Alan Prem Kumar National University of Singapore
Wee Joo Chng
Wee Joo Chng National University of Singapore
Gautam Sethi
Gautam Sethi National University of Singapore
Chandra S. Verma
Chandra S. Verma Agency for Science, Technology and Research
Chai Quek
Chai Quek Nanyang Technological University
Peter E. Lobie
Peter E. Lobie Tsinghua University
Jay T. Groves
Jay T. Groves University of California, Berkeley
H. Phillip Koeffler
H. Phillip Koeffler Cedars-Sinai Medical Center
Clare L. Scott
Clare L. Scott Walter and Eliza Hall Institute of Medical Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology or Biochemistry in the USA can open doors to a diverse array of healthcare careers. Online degree options now make these pathways more accessible than ever, especially for working professionals or students who need flexible schedules.

If you’re interested in direct patient care, several registered nurse online programs provide comprehensive training and the qualifications needed to enter high-demand nursing roles.

For those passionate about wellness and the science behind food, an online degree in nutrition can lead to roles in dietetics, public health, or research.

Many graduates pursue leadership in healthcare management, and top online mha programs that are cahme accredited offer targeted training for these roles. These programs can pave the way for careers in hospital administration and healthcare policy.

For advanced practice nurses and those aiming for terminal degrees, there are also dnp program no clinical options, allowing clinical professionals to earn a doctorate with more flexible requirements.

As online education continues to expand, these varied degree tracks provide exciting opportunities for students interested in the life sciences to launch or advance rewarding careers in healthcare.

Best Scientists Citing Tuan Zea Tan

Trending Scientists

Recently Published Articles