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Biology and Biochemistry

D-Index
80
Citations
20210
World Ranking
4145
National Ranking
12

Overview

Vinay Tergaonkar is affiliated with the Agency for Science, Technology and Research in Singapore. Their research centers on biochemistry, genetics, and molecular biology, with a significant focus on molecular biology, cancer research, immunology, oncology, and biomedical engineering.

Their work covers several main topics, including:

  • Genomics and Chromatin Dynamics
  • Cancer-related molecular mechanisms research
  • NF-κB Signaling Pathways
  • Ubiquitin and proteasome pathways
  • RNA Research and Splicing
  • 3D Printing in Biomedical Research
  • Interferon and immune responses

Recent research contributions by Tergaonkar include:

  • H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions, 2021, Nature Communications
  • NF-κB as a regulator of cancer metastasis and therapy response: A focus on epithelial-mesenchymal transition, 2022, Journal of Cellular Physiology
  • Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?, 2021, Cancer Letters
  • Unraveling B cell trajectories at single cell resolution, 2022, Trends in Immunology
  • Small Molecule NF-κB Pathway Inhibitors in Clinic, 2020, International Journal of Molecular Sciences

Frequent co-authors who have collaborated with Tergaonkar include:

  • Melissa J. Fullwood
  • Gautam Sethi
  • Semih Can Akıncılar
  • Yichao Cai
  • Anandhkumar Raju

Tergaonkar has been published across several key journals and publication venues, most notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Letters
  • Trends in Immunology
  • Nature Cell Biology

Best Publications

  • IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

    James E. Vince;W. Wei-Lynn Wong;Nufail Khan;Rebecca Feltham

  • A fourth IκB protein within the NF-κB signaling module

    Soumen Basak;Hana Kim;Jeffrey D. Kearns;Vinay Tergaonkar

  • A circRNA from SEPALLATA3 regulates splicing of its cognate mRNA through R-loop formation

    Vanessa M. Conn;Vanessa M. Conn;Veronique Hugouvieux;Aditya Nayak;Stephanie A. Conos

  • p53 stabilization is decreased upon NFκB activation

    Vinay Tergaonkar;Matthew Pando;Omid Vafa;Geoffrey Wahl

  • Telomerase directly regulates NF-κB-dependent transcription

    Arkasubhra Ghosh;Gaye Saginc;Shi Chi Leow;Ekta Khattar

  • NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration.

    Claudio Mauro;Shi Chi Leow;Elena Anso;Sonia Rocha

  • Multifaceted link between cancer and inflammation

    Gautam Sethi;Muthu K. Shanmugam;Lalitha Ramachandran;Alan Prem Kumar

  • Chronic adipose tissue inflammation: all immune cells on the stage

    Gökhan Cildir;Gökhan Cildir;Semih Can Akıncılar;Semih Can Akıncılar;Vinay Tergaonkar;Vinay Tergaonkar

  • NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy

    Han-Ming Shen;Vinay Tergaonkar

  • NFκB pathway: A good signaling paradigm and therapeutic target

    Vinay Tergaonkar

  • Telomerase: central regulator of all of the hallmarks of cancer

    Kee Chung Low;Vinay Tergaonkar;Vinay Tergaonkar

  • Noncanonical NF-κB Signaling in Health and Disease

    Gökhan Cildir;Gökhan Cildir;Kee Chung Low;Vinay Tergaonkar;Vinay Tergaonkar;Vinay Tergaonkar

  • Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.

    Hsiangling Teo;Sourav Ghosh;Hendrik Luesch;Hendrik Luesch;Arkasubhra Ghosh

  • Roles of NF-κB in health and disease : mechanisms and therapeutic potential

    Ee Tsin Wong;Vinay Tergaonkar

  • Potential pharmacological control of the NF-κB pathway

    Gautam Sethi;Vinay Tergaonkar;Vinay Tergaonkar

  • IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy.

    Vinay Tergaonkar;Virginie Bottero;Masahito Ikawa;Qiutang Li

  • Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

    Muthu K Shanmugam;Jong Hyun Lee;Edna Zhi Pei Chai;Madhu Mathi Kanchi

  • ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress

    Zhao Hui Wu;Zhao Hui Wu;Ee Tsin Wong;Yuling Shi;Jixiao Niu

  • H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions

    Yichao Cai;Ying Zhang;Yan Ping Loh;Jia Qi Tng

  • Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.

    Yinghui Li;Qi Ling Zhou;Wenjie Sun;Prashant Chandrasekharan

Frequent Co-Authors

Motomi Osato
Motomi Osato National University of Singapore
Gautam Sethi
Gautam Sethi National University of Singapore
Angel F. Lopez
Angel F. Lopez University of South Australia
Alan Prem Kumar
Alan Prem Kumar National University of Singapore
Weiping Han
Weiping Han Institute of Molecular and Cell Biology
Wanjin Hong
Wanjin Hong Agency for Science, Technology and Research
Yat Li
Yat Li University of California, Santa Cruz
Stuart M. Pitson
Stuart M. Pitson University of South Australia
Michael W. Parker
Michael W. Parker University of Melbourne
Yoshiaki Ito
Yoshiaki Ito National University of Singapore

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