World's Best Scientists 2026 revealed!
Ralph Müller

Ralph Müller

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Engineering and Technology
Switzerland
2026
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Medicine
Switzerland
2023

D-Index & Metrics

Engineering and Technology

D-Index
114
Citations
47055
World Ranking
70
National Ranking
1

Medicine

D-Index
120
Citations
51394
World Ranking
3763
National Ranking
45

Research.com Recognitions

  • 2026 - Research.com Engineering and Technology in Switzerland Leader Award
  • 2025 - Research.com Engineering and Technology in Switzerland Leader Award
  • 2023 - Research.com Medicine in Switzerland Leader Award
  • 2022 - Research.com Engineering and Technology in Switzerland Leader Award

Overview

Ralph Müller is affiliated with ETH Zurich in Switzerland and is active in multiple research areas bridging medicine, engineering, and biochemistry. Their work has a strong focus on bone health, orthopedic treatments, and biomedical engineering applications.

The scientist's main fields of study include Medicine with 165 publications, Engineering with 103, and Biochemistry, Genetics and Molecular Biology with 78. Subfields in which they have contributed significantly include Biomedical Engineering (88 publications), Molecular Biology (46), Orthopedics and Sports Medicine (42), Surgery (25), and Radiology, Nuclear Medicine and Imaging (23).

Their research covers a range of topics primarily related to bone science and biomedical technologies. Key topics include:

  • Bone health and osteoporosis research
  • 3D Printing in Biomedical Research
  • Bone Tissue Engineering Materials
  • Bone Metabolism and Diseases
  • Bone fractures and treatments
  • Medical Imaging Techniques and Applications
  • Orthopaedic implants and arthroplasty

Recent notable papers authored by or associated with Ralph Müller include:

  • Application of subject-specific adaptive mechanical loading for bone healing in a mouse tail vertebral defect, 2021, Scientific Reports
  • Bone fragility in diabetes: novel concepts and clinical implications, 2022, The Lancet Diabetes & Endocrinology
  • 3D Bioprinting of Human Tissues: Biofabrication, Bioinks, and Bioreactors, 2021, International Journal of Molecular Sciences
  • 3D bioprinting of graphene oxide-incorporated cell-laden bone mimicking scaffolds for promoting scaffold fidelity, osteogenic differentiation and mineralization, 2020, Acta Biomaterialia
  • Tomographic volumetric bioprinting of heterocellular bone-like tissues in seconds, 2022, Acta Biomaterialia

Frequent collaborators in their research include:

  • Gisela Kuhn
  • Esther Wehrle
  • Xiao-Hua Qin
  • Marina Rubert
  • Caitlyn J. Collins

Their work has been published in several venues with multiple contributions, notably:

  • bioRxiv (Cold Spring Harbor Laboratory) with 32 publications
  • Bone, 9 publications
  • Frontiers in Bioengineering and Biotechnology, 8 publications
  • Scientific Reports, 7 publications
  • Bone Reports, 7 publications

Ralph Müller also contributed as an author to a book published by Cambridge University Press titled Seemed Like a Good Idea (2022).

Best Publications

  • Guidelines for assessment of bone microstructure in rodents using micro–computed tomography

    Mary L Bouxsein;Stephen K Boyd;Blaine A Christiansen;Robert E Guldberg

  • Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus.

    Tor Hildebrand;Andres Laib;Ralph Müller;Jan Dequeker

  • A MICROTOMOGRAPHIC SYSTEM FOR THE NONDESTRUCTIVE EVALUATION OF BONE ARCHITECTURE

    P. Rüegsegger;B. Koller;R. Müller

  • Repair of bone defects using synthetic mimetics of collagenous extracellular matrices.

    Matthias P. Lutolf;Franz E. Weber;Hugo G. Schmoekel;Jason C. Schense

  • Morphometric Analysis of Human Bone Biopsies: A Quantitative Structural Comparison of Histological Sections and Micro-Computed Tomography

    Ralph Müller;Ralph Müller;H. Van Campenhout;B. Van Damme;G. Van Der Perre

  • TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis.

    Allison R. Pettit;Hong Ji;Dietrich von Stechow;Ralph Müller;Ralph Müller

  • EMAG2: A 2-arc min resolution Earth Magnetic Anomaly Grid compiled from satellite, airborne, and marine magnetic measurements

    S. Maus;S. Maus;U. Barckhausen;H. Berkenbosch;N. Bournas

  • Application of subject-specific adaptive mechanical loading for bone healing in a mouse tail vertebral defect.

    Angad Malhotra;Matthias Walle;Graeme R. Paul;Gisela A. Kuhn

  • Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study.

    David W. Dempster;David W. Dempster;Felicia Cosman;Felicia Cosman;Etah S. Kurland;Hua Zhou

  • Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing

    A. Butscher;M. Bohner;S. Hofmann;Ludwig J. Gauckler

  • The Receptor Kinase CORYNE of Arabidopsis Transmits the Stem Cell–Limiting Signal CLAVATA3 Independently of CLAVATA1

    Ralf Müller;Andrea Bleckmann;Rüdiger Simon

  • Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing.

    Mikaël M. Martino;Priscilla S. Briquez;Esra Güç;Federico Tortelli

  • Osteal Macrophages Promote In Vivo Intramembranous Bone Healing in a Mouse Tibial Injury Model

    Kylie A Alexander;Ming K Chang;Erin R Maylin;Thomas Kohler

  • Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

    Mikaël M. Martino;Federico Tortelli;Mayumi Mochizuki;Stephanie Traub

  • Architecture and properties of anisotropic polymer composite scaffolds for bone tissue engineering

    Laurence Marcelle Mathieu;Thomas L Mueller;Pierre-Etienne Bourban;Dominique P Pioletti

  • Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention.

    Clinton Rubin;A. Simon Turner;Ralph Müller;Erik Mittra

  • Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds.

    Sandra Hofmann;Henri Hagenmüller;Annette M. Koch;Ralph Müller

  • Engineering craniofacial scaffolds

    Scott J. Hollister;C. Y. Lin;E. Saito;R. D. Schek

  • Tunable hydrogel composite with two-step processing in combination with innovative hardware upgrade for cell-based three-dimensional bioprinting.

    Silke Wüst;Marie E. Godla;Ralph Müller;Sandra Hofmann

  • Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone

    Ralph Müller;Tor Hildebrand;Peter Rüegsegger

Frequent Co-Authors

Leah Rae Donahue
Leah Rae Donahue The Jackson Laboratory
Felix Eckstein
Felix Eckstein Paracelsus Medical University
Jeffrey A. Hubbell
Jeffrey A. Hubbell New York University
Marc Bohner
Marc Bohner RMS Foundation
Jens-Uwe Grooß
Jens-Uwe Grooß Forschungszentrum Jülich
David W. Dempster
David W. Dempster Columbia University
Elizabeth Shane
Elizabeth Shane Columbia University
Dan Gazit
Dan Gazit Cedars-Sinai Medical Center
Sundeep Khosla
Sundeep Khosla Mayo Clinic
Robert R. Recker
Robert R. Recker Creighton University

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