Kazuo Umezawa

Overview

Best Publications

• Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs.

  Siro Simizu;Minoru Takada;Kazuo Umezawa;Masaya Imoto

  387
  Citations

• Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus

  Toshihiko Onoda;Hironobu Iinuma;Yumi Sasaki;Masa Hamada

  353
  Citations

• Inhibition of Tumor Necrosis Factor-α-induced Nuclear Translocation and Activation of NF-κB by Dehydroxymethylepoxyquinomicin

  Akiko Ariga;Jun-ichi Namekawa;Naoki Matsumoto;Jun-ichiro Inoue

  293
  Citations

• Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C

  Naoki Matsumoto;Akiko Ariga;Sakino To-e;Hikaru Nakamura

  237
  Citations

• Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-κB pathway

  Norihiro Nagai;Kanako Izumi-Nagai;Yuichi Oike;Takashi Koto

  225
  Citations

• Production, isolation and structure determination of a novel beta-glucosidase inhibitor, cyclophellitol, from Phellinus sp.

  Sonoko Atsumi;Kazuo Umezawa;Hironobu Iinuma;Hiroshi Naganawa

  210
  Citations

• Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors.

  Kazuo Umezawa;Takashi Hori;Hirohisa Tajima;Masaya Imoto

  195
  Citations

• Macular Pigment Lutein Is Antiinflammatory in Preventing Choroidal Neovascularization

  Kanako Izumi-Nagai;Norihiro Nagai;Kazuhiro Ohgami;Shingo Satofuka

  194
  Citations

• Phenacyl photosensitive blocking groups

  John C. Sheehan;Kazuo Umezawa

  182
  Citations

• Dual targeting of transformed and untransformed HTLV-1–infected T cells by DHMEQ, a potent and selective inhibitor of NF-κB, as a strategy for chemoprevention and therapy of adult T-cell leukemia

  Mariko Watanabe;Takeo Ohsugi;Momoko Shoda;Takaomi Ishida

  181
  Citations

• Synthesis of N-substituted N-nitrosohydroxylamines as inhibitors of mushroom tyrosinase.

  Mitsuhiro Shiino;Yumi Watanabe;Kazuo Umezawa

  178
  Citations

• TGF-β-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells

  Mikiko Kawata;Daizo Koinuma;Tomohiro Ogami;Kazuo Umezawa

  172
  Citations

• Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.

  Miyuki Kubota;Shigeto Shimmura;Shunsuke Kubota;Hideyuki Miyashita

  170
  Citations

• Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis

  Yusuke N. Kimura;Kosuke Watari;Abbas Fotovati;Fumihito Hosoi

  170
  Citations

• JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD30 promoter in anaplastic large cell lymphoma and reed-sternberg cells of Hodgkin lymphoma.

  Mariko Watanabe;Masataka Sasaki;Kinji Itoh;Masaaki Higashihara

  169
  Citations

• Inhibition of RANKL‐Induced Osteoclastogenesis by (−)‐DHMEQ, a Novel NF‐κB Inhibitor, Through Downregulation of NFATc1

  Hiroshi Takatsuna;Masataka Asagiri;Takeshi Kubota;Kotaro Oka

  165
  Citations

• Similarity of teleocidin B and phorbol ester tumour promoters in effects on membrane receptors

  Kazuo Umezawa;I. Bernard Weinstein;Ann Horowitz;Hirota Fujiki

  159
  Citations

• BRAFV600E Promotes Invasiveness of Thyroid Cancer Cells through Nuclear Factor κB Activation

  Iryna Palona;Hiroyuki Namba;Norisato Mitsutake;Dmytro Starenki

  153
  Citations

• Induction of normal phenotypes in ras-transformed cells by damnacanthal from Morinda citrifolia

  Tomonori Hiramatsu;Masaya Imoto;Takashi Koyano;Kazuo Umezawa

  147
  Citations

• Targeting of Nuclear Factor κB Pathways by Dehydroxymethylepoxyquinomicin, a Novel Inhibitor of Breast Carcinomas: Antitumor and Antiangiogenic Potential In vivo

  Gaku Matsumoto;Jun Ichi Namekawa;Mariko Muta;Tadahiko Nakamura

  146
  Citations