Jun-ichiro Inoue

Overview

Best Publications

• Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.

  Hiroshi Takayanagi;Sunhwa Kim;Takako Koga;Takako Koga;Hiroshi Nishina

  2845
  Citations

• TAK1 is a ubiquitin-dependent kinase of MKK and IKK

  Chen Wang;Li Deng;Mei Hong;Giridhar R. Akkaraju

  2633
  Citations

• Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes.

  Taro Kawai;Osamu Takeuchi;Takashi Fujita;Jun-ichiro Inoue

  1626
  Citations

• The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

  Jun Ninomiya-Tsuji;Kazuya Kishimoto;Atsushi Hiyama;Jun-ichiro Inoue

  1495
  Citations

• Interferon-|[alpha]| induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

  Taro Kawai;Shintaro Sato;Ken J. Ishii;Cevayir Coban

  1306
  Citations

• Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice.

  Asuka Naito;Sakura Azuma;Sakae Tanaka;Tsuyoshi Miyazaki

  777
  Citations

• Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

  J Inoue;M Seiki;T Taniguchi;S Tsuru

  605
  Citations

• Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region

  Takaomi Ishida;Sei-ichi Mizushima;Sakura Azuma;Norihiko Kobayashi

  595
  Citations

• The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

  Taishin Akiyama;Yusuke Shimo;Hiromi Yanai;Junwen Qin

  581
  Citations

• Tumor Necrosis Factor Receptor-Associated Factor (TRAF) Family: Adapter Proteins That Mediate Cytokine Signaling

  Jun ichiro Inoue;Takaomi Ishida;Nobuo Tsukamoto;Norihiko Kobayashi

  548
  Citations

• Segregation of TRAF6‐mediated signaling pathways clarifies its role in osteoclastogenesis

  Norihiko Kobayashi;Yuho Kadono;Yuho Kadono;Asuka Naito;Kunihiro Matsumoto

  547
  Citations

• Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

  Fumiyo Ikeda;Riko Nishimura;Takuma Matsubara;Sakae Tanaka

  513
  Citations

• TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

  Takaomi Ishida;Tadashi Tojo;Tsutomu Aoki;Norihiko Kobayashi

  504
  Citations

• Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.

  Mitsuo Maruyama;Hiroshi Shibuya;Hisashi Harada;Masanori Hatakeyama

  496
  Citations

• The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

  Yu Hikosaka;Takeshi Nitta;Izumi Ohigashi;Kouta Yano

  490
  Citations

• IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases

  Takahiro Shimada;Taro Kawai;Kiyoshi Takeda;Makoto Matsumoto

  469
  Citations

• Cutting Edge: TNFR-Associated Factor (TRAF) 6 Is Essential for MyD88-Dependent Pathway but Not Toll/IL-1 Receptor Domain-Containing Adaptor-Inducing IFN-β (TRIF)-Dependent Pathway in TLR Signaling

  Jin Gohda;Takayuki Matsumura;Jun-ichiro Inoue

  416
  Citations

• Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay

  Mizuki Yamamoto;Shutoku Matsuyama;Xiao Li;Makoto Takeda

  405
  Citations

• TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase.

  Anastassia Hatzoglou;Jérôme Roussel;Marie-Françoise Bourgeade;Edith Rogier

  366
  Citations

• IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family

  Jun-ichiro Inoue;Lawrence D. Kerr;Akira Kakizuka;Inder M. Verma

  364
  Citations