World's Best Scientists 2026 revealed!
Hidenori Ichijo

Hidenori Ichijo

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
120
Citations
60471
World Ranking
630
National Ranking
26

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Hidenori Ichijo is affiliated with the University of Tokyo in Japan and works primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine. Their research output includes 64 publications in biochemistry-related disciplines and 50 in medical sciences. The main subfields of study associated with their work are Molecular Biology, Physiology, Immunology, Cell Biology, and Epidemiology.

Their research covers a range of main topics including Adipose Tissue and Metabolism, Redox Biology and Oxidative Stress, RNA Research and Splicing, Heat Shock Proteins Research, Endoplasmic Reticulum Stress and Disease, Genomics, Phytochemicals and Oxidative Stress, as well as Telomeres, Telomerase, and Senescence.

Hidenori Ichijo's recent papers reflect a focus on cellular stress responses and regulated cell death processes. Notable publications include:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023" (2023) published in Cell Death and Differentiation
  • "A guideline on the molecular ecosystem regulating ferroptosis" (2024) published in Nature Cell Biology
  • "Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)" (2021) published in Nature Communications
  • "The mitochondrial Ca 2+ uptake regulator, MICU1, is involved in cold stress-induced ferroptosis" (2021) published in EMBO Reports
  • "Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation" (2020) published in Communications Biology

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, Communications Biology, Scientific Reports, and Nature Communications. The number of contributions in these journals ranges from three to ten publications.

Collaborations are a significant aspect of Ichijo's research. Frequent co-authors include Isao Naguro, Takao Fujisawa, Kengo Watanabe, Kazuhiro Morishita, and Kazuki Hattori, with collaboration counts varying from seven to twenty-eight joint works.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

    Masao Saitoh;Hideki Nishitoh;Makiko Fujii;Kohsuke Takeda

  • Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

    Hidenori Ichijo;Eisuke Nishida;Kenji Irie;Peter ten Dijke

  • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

    Hideki Nishitoh;Atsushi Matsuzawa;Kei Tobiume;Kaoru Saegusa

  • BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

    Kazuhito Yamamoto;Hidenori Ichijo;Stanley J. Korsmeyer

  • ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

    Kei Tobiume;Atsushi Matsuzawa;Takumi Takahashi;Hideki Nishitoh

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor.

    P Franzén;P ten Dijke;H Ichijo;H Yamashita

  • Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

    P. ten Dijke;H. Yamashita;T.K. Sampath;A.H. Reddi

  • Apoptosis inhibitory activity of cytoplasmic p21Cip1/WAF1 in monocytic differentiation

    Minoru Asada;Takayuki Yamada;Hidenori Ichijo;Hidenori Ichijo;Domenico Delia

  • Characterization of Type I Receptors for Transforming Growth Factor-β and Activin

    P ten Dijke;H Yamashita;H Ichijo;H Ichijo;P Franzen

  • ASK1 Is Essential for JNK/SAPK Activation by TRAF2

    Hideki Nishitoh;Masao Saitoh;Masao Saitoh;Yoshiyuki Mochida;Yoshiyuki Mochida;Kohsuke Takeda;Kohsuke Takeda

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

    Atsushi Matsuzawa;Kaoru Saegusa;Takuya Noguchi;Chiharu Sadamitsu

  • From receptors to stress-activated MAP kinases.

    Hidenori Ichijo

  • Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by the Adapter Protein Daxx

    Howard Y. Chang;Hideki Nishitoh;Xiaolu Yang;Hidenori Ichijo

  • Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by Tumor Necrosis Factor Receptor-Associated Factor 2 Requires Prior Dissociation of the ASK1 Inhibitor Thioredoxin

    Hong Liu;Hideki Nishitoh;Hidenori Ichijo;John M. Kyriakis

  • ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

    Hideki Nishitoh;Hisae Kadowaki;Atsushi Nagai;Takeshi Maruyama

  • Roles of Bone Morphogenetic Protein Type I Receptors and Smad Proteins in Osteoblast and Chondroblast Differentiation

    M Fujii;K Takeda;T Imamura;H Aoki

  • Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling.

    Atsushi Matsuzawa;Hidenori Ichijo

Frequent Co-Authors

Kohsuke Takeda
Kohsuke Takeda Nagasaki University
Hideki Nishitoh
Hideki Nishitoh University of Miyazaki
Atsushi Matsuzawa
Atsushi Matsuzawa Tohoku University
Kohei Miyazono
Kohei Miyazono University of Tokyo
Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Christer Wernstedt
Christer Wernstedt Ludwig Cancer Research
Ulf Hellman
Ulf Hellman Ludwig Cancer Research
Hisao Ogawa
Hisao Ogawa Kumamoto University
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Lars Rönnstrand
Lars Rönnstrand Lund University

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