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Kohei Miyazono

Kohei Miyazono

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Molecular Biology
Japan
2026
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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
159
Citations
99869
World Ranking
67
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Japan Leader Award
  • 2025 - Research.com Molecular Biology in Japan Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Molecular Biology in Japan Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kohei Miyazono is affiliated with the University of Tokyo in Japan and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on molecular biology and oncology, with significant work in cancer research, pulmonary and respiratory medicine, and immunology.

The scientist's main research topics include:

  • TGF-β signaling in diseases
  • Cancer cells and metastasis
  • Epigenetics and DNA methylation
  • Renal and related cancers
  • Cell image analysis techniques
  • Cancer, hypoxia, and metabolism
  • Heterotopic ossification and related conditions

Notable recent papers authored or co-authored by Kohei Miyazono include:

  • TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation (2020), published in Cancer Science
  • Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series (2020), published in Critical Care
  • Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis (2020), published in Nature Cell Biology
  • TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness (2020), published in Oncogene
  • Bone Morphogenetic Protein Signaling in Cancer; Some Topics in the Recent 10 Years (2022), published in Frontiers in Cell and Developmental Biology

Frequent publication venues where Kohei Miyazono's work has appeared include:

  • Cancer Science
  • Molecular Oncology
  • Journal of Biological Chemistry
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • STAR Protocols

The scientist collaborates regularly with a number of co-authors, including:

  • Daizo Koinuma
  • Shogo Ehata
  • Kei Takahashi
  • Jun Nishida
  • Masato Morikawa

Throughout their career, Kohei Miyazono has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an honor awarded in 2012.

Best Publications

  • TGF-beta signalling from cell membrane to nucleus through SMAD proteins

    Carl-Henrik Heldin;Kohei Miyazono;Peter ten Dijke

  • Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

    Masao Saitoh;Hideki Nishitoh;Makiko Fujii;Kohsuke Takeda

  • Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

    Hidenori Ichijo;Eisuke Nishida;Kenji Irie;Peter ten Dijke

  • Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

    H. Cabral;Y. Matsumoto;K. Mizuno;Q. Chen

  • Modulation of microRNA processing by p53

    Hiroshi I. Suzuki;Kaoru Yamagata;Koichi Sugimoto;Takashi Iwamoto

  • TGFβ signalling: a complex web in cancer progression

    Hiroaki Ikushima;Kohei Miyazono

  • ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

    Kei Tobiume;Atsushi Matsuzawa;Takumi Takahashi;Hideki Nishitoh

  • Smad6 inhibits signalling by the TGF-Beta superfamily

    Takeshi Imamura;Masao Takase;Ayako Nishihara;Eiichi Oeda

  • TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.

    Atsuhito Nakao;Takeshi Imamura;Takeshi Imamura;Serhiy Souchelnytskyi;Masahiro Kawabata

  • Bone morphogenetic protein receptors and signal transduction

    Kohei Miyazono;Yuto Kamiya;Masato Morikawa

  • Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

    Toshio Kitamura;Tsuyoshi Tange;Takashi Terasawa;Shigeru Chiba

  • TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

    Masato Morikawa;Rik Derynck;Kohei Miyazono

  • Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

    Takanori Ebisawa;Minoru Fukuchi;Gyo Murakami;Tomoki Chiba

  • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk

    Kohei Miyazono;Kohei Miyazono;Shingo Maeda;Takeshi Imamura

  • Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

    S. Paul Oh;Tsugio Seki;Kendrick A. Goss;Takeshi Imamura

  • TGF-β signaling by Smad proteins

    Kohei Miyazono

  • Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300.

    Kinichi Nakashima;Makoto Yanagisawa;Hirokazu Arakawa;Naoki Kimura

  • Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor.

    P Franzén;P ten Dijke;H Ichijo;H Yamashita

  • Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

    K Miyazono;U Hellman;C Wernstedt;C H Heldin

  • Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.

    Fuyuki Ishikawa;Kohei Miyazono;Kohei Miyazono;Ulf Hellman;Hannes Drexler

Frequent Co-Authors

Takeshi Imamura
Takeshi Imamura Ehime University
Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Tetsuro Watabe
Tetsuro Watabe Tokyo Medical and Dental University
Keiji Miyazawa
Keiji Miyazawa University of Yamanashi
Hidenori Ichijo
Hidenori Ichijo University of Tokyo
Masahiro Kawabata
Masahiro Kawabata Japanese Foundation For Cancer Research
Fumimaro Takaku
Fumimaro Takaku University of Tokyo
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Ulf Hellman
Ulf Hellman Ludwig Cancer Research
Yasuyuki Morishita
Yasuyuki Morishita University of Tokyo

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