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Best Scientists
2025
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Biology and Biochemistry
USA
2026

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Best Scientists

D-Index
215
Citations
224338
World Ranking
162
National Ranking
109

Biology and Biochemistry

D-Index
216
Citations
231430
World Ranking
23
National Ranking
20

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2012 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2008 - BBVA Foundation Frontiers of Knowledge Award
  • 2006 - Member of the National Academy of Medicine (NAM)
  • 2000 - Member of the National Academy of Sciences
  • 1999 - Fellow of the American Academy of Arts and Sciences

Overview

Joan Massagué is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, the focus narrows further to subfields such as Molecular Biology, Oncology, Cell Biology, Pulmonary and Respiratory Medicine, and Cancer Research.

The main topics addressed in their research include:

  • Cancer Cells and Metastasis
  • Epigenetics and DNA Methylation
  • TGF-β signaling in diseases
  • Cancer Research and Treatments
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Cellular Mechanics and Interactions

Joan Massagué has contributed to several recent publications, which demonstrate a focus on molecular mechanisms and cancer metastasis pathways. Notable papers include:

  • "Guidelines and definitions for research on epithelial-mesenchymal transition," 2020, published in Nature Reviews Molecular Cell Biology
  • "Targeting metastatic cancer," 2021, published in Nature Medicine
  • "TGF-β signaling in health and disease," 2023, published in Cell
  • "Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients," 2022, published in Cell
  • "TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1," 2020, published in Nature

Their research outputs have frequently appeared in the following publication venues:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Cancer
  • Cell

Collaborations have been formed with several frequent co-authors, including:

  • Anna-Katerina Hadjantonakis
  • Karuna Ganesh
  • Harihar Basnet
  • Ekrem Emrah Er
  • Dana Pe'er

Joan Massagué has been recognized with multiple awards and honors throughout their academic career, such as:

  • Robert J. and Claire Pasarow Foundation Medical Research Award (2012)
  • BBVA Foundation Frontiers of Knowledge Award (2008)
  • Member of the National Academy of Medicine (2006)
  • Member of the National Academy of Sciences (2000)
  • Fellow of the American Academy of Arts and Sciences (1999)

Best Publications

  • TGF-beta signal transduction.

    Massagué J

  • Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus

    Yigong Shi;Joan Massagué

  • Cancer Metastasis: Building a Framework

    Gaorav P. Gupta;Joan Massagué

  • TGFβ in Cancer

    Joan Massagué

  • The transforming growth factor-beta family.

    Joan Massague

  • Genes that mediate breast cancer metastasis to lung

    Andy J. Minn;Gaorav P. Gupta;Peter M. Siegel;Peter M. Siegel;Paula D. Bos

  • TGFβ signalling in context.

    Joan Massagué

  • Mechanism of activation of the TGF-β receptor

    Jeffrey L. Wrana;Liliana Attisano;Rotraud Wieser;Francesc Ventura

  • TGFBETA SIGNALING IN GROWTH CONTROL, CANCER, AND HERITABLE DISORDERS

    Joan Massagué;Stacy W Blain;Roger S Lo

  • Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

    R A Ignotz;J Massagué

  • A multigenic program mediating breast cancer metastasis to bone.

    Yibin Kang;Peter M. Siegel;Weiping Shu;Maria Drobnjak

  • Metastasis: from dissemination to organ-specific colonization

    Don X. Nguyen;Paula D. Bos;Joan Massagué

  • Smad transcription factors

    Joan Massagué;Joan Seoane;David Wotton

  • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

    Kornelia Polyak;Mong Hong Lee;Hediye Erdjument-Bromage;Andrew Koff

  • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

    Kornelia Polyak;Jun-ya Kato;Mark J. Solomon;Charles J. Sherr

  • How cells read TGF-beta signals.

    Joan Massagué

  • Transcriptional control by the TGF‐β/Smad signaling system

    Joan Massagué;David Wotton

  • Controlling TGF-β signaling

    Joan Massagué;Ye-Guang Chen

  • Endogenous human microRNAs that suppress breast cancer metastasis

    Sohail F. Tavazoie;Claudio Alarcón;Thordur Oskarsson;David Padua

  • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer.

    Peter M. Siegel;Joan Massagué

Frequent Co-Authors

Michael P. Czech
Michael P. Czech University of Massachusetts Chan Medical School
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Yibin Kang
Yibin Kang Princeton University
Liliana Attisano
Liliana Attisano University of Toronto
Xiang Zhang
Xiang Zhang University of Hong Kong
Larry Norton
Larry Norton Memorial Sloan Kettering Cancer Center
Kornelia Polyak
Kornelia Polyak Harvard University
Ye-Guang Chen
Ye-Guang Chen Tsinghua University
William L. Gerald
William L. Gerald Memorial Sloan Kettering Cancer Center
Joan Seoane
Joan Seoane Institució Catalana de Recerca i Estudis Avançats

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