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Biology and Biochemistry

D-Index
59
Citations
23529
World Ranking
12260
National Ranking
243

Overview

Joan Seoane is a researcher affiliated with the Institució Catalana de Recerca i Estudis Avançats located in Spain. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a specialized focus on Oncology and Molecular Biology. Additional subfields of study include Cancer Research, Genetics, and Immunology.

The main topics covered in Joan Seoane's research include:

  • Cancer Genomics and Diagnostics
  • Glioma Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Single-cell and spatial transcriptomics
  • Immune cells in cancer
  • CAR-T cell therapy research
  • Genetic factors in colorectal cancer

Joan Seoane has contributed to a number of scientific publications, showing a frequent presence in several prominent journals. The main publication venues are:

  • Annals of Oncology
  • Cancer Research
  • ESMO Open
  • Clinical Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent research papers by Joan Seoane include:

  • ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group, 2022, Annals of Oncology
  • EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours, 2021, Annals of Oncology
  • Clinical development of therapies targeting TGFβ: current knowledge and future perspectives, 2020, Annals of Oncology
  • A single-cell tumor immune atlas for precision oncology, 2021, Genome Research
  • Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures, 2020, Frontiers in Immunology

Frequently collaborating with Joan Seoane are the following co-authors:

  • Josep Tabernero
  • Paolo Nucíforo
  • Francisco Martínez-Ricarte
  • Raffaella Iurlaro
  • Isabel Cuartas

Best Publications

  • Smad transcription factors

    Joan Massagué;Joan Seoane;David Wotton

  • Patient-derived xenograft models: an emerging platform for translational cancer research.

    Manuel Hidalgo;Frederic Amant;Andrew V. Biankin;Eva Budinská

  • Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation.

    Joan Seoane;Hong Van Le;Lijian Shen;Stewart A. Anderson

  • Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

    Priscilla K. Brastianos;Scott L. Carter;Scott L. Carter;Sandro Santagata;Sandro Santagata;Daniel P. Cahill

  • Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

    Joan Seoane;Hong-Van Le;Joan Massagué

  • Repression of p15INK4b expression by Myc through association with Miz-1.

    Peter Staller;Karen Peukert;Astrid Kiermaier;Joan Seoane

  • Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

    Leticia De Mattos-Arruda;Leticia De Mattos-Arruda;Leticia De Mattos-Arruda;Regina Mayor;Charlotte K. Y. Ng;Britta Weigelt

  • TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

    Judit Anido;Andrea Sáez-Borderías;Alba Gonzàlez-Juncà;Laura Rodón

  • TGFbeta Influences Myc, Miz-1 and Smad to Control the CDK Inhibitor p15INK4b

    Joan Seoane;Celio Pouponnot;Peter Staller;Manuela Schader

  • Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Annette T. Byrne;Denis G. Alférez;Frédéric Amant;Daniela Annibali

  • TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma.

    Silvia Peñuelas;Judit Anido;Rosa M. Prieto-Sánchez;Gerard Folch

  • Phosphatidylinositol 3-Kinase Hyperactivation Results in Lapatinib Resistance that Is Reversed by the mTOR/Phosphatidylinositol 3-Kinase Inhibitor NVP-BEZ235

    Pieter J.A. Eichhorn;Magüi Gili;Maurizio Scaltriti;Violeta Serra

  • High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene

    Alejandra Bruna;Rachel S. Darken;Federico Rojo;Alberto Ocaña

  • OAZ Uses Distinct DNA- and Protein-Binding Zinc Fingers in Separate BMP-Smad and Olf Signaling Pathways

    Akiko Hata;Joan Seoane;Giorgio Lagna;Ermelinda Montalvo

  • TGF-β Family Signaling in Tumor Suppression and Cancer Progression.

    Joan Seoane;Roger R. Gomis

  • USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

    Pieter J A Eichhorn;Laura Rodón;Alba Gonzàlez-Juncà;Annette Dirac

  • Crystal Structure of a Phosphorylated Smad2: Recognition of Phosphoserine by the MH2 Domain and Insights on Smad Function in TGF-β Signaling

    Jia-Wei Wu;Min Hu;Jijie Chai;Joan Seoane

  • Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle

    L. De Mattos-Arruda;L. De Mattos-Arruda;L. De Mattos-Arruda;B. Weigelt;J. Cortes;H.H. Won

  • Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.

    Beverley J. Warner;Stacy W. Blain;Joan Seoane;Joan Massagué

  • A FoxO–Smad synexpression group in human keratinocytes

    Roger R. Gomis;Claudio Alarcón;Wei He;Qiongqing Wang

Frequent Co-Authors

Josep Tabernero
Josep Tabernero Vall d´Hebron Institute of Oncology
José Baselga
José Baselga Memorial Sloan Kettering Cancer Center
Javier Cortes
Javier Cortes Vall d'Hebron Hospital Universitari
Enriqueta Felip
Enriqueta Felip Vall d'Hebron Institut de Recerca
Carlos Caldas
Carlos Caldas University of Cambridge
Joan Massagué
Joan Massagué Memorial Sloan Kettering Cancer Center
Jorge S. Reis-Filho
Jorge S. Reis-Filho Memorial Sloan Kettering Cancer Center
Joaquín Arribas
Joaquín Arribas Institució Catalana de Recerca i Estudis Avançats
Charlotte K.Y. Ng
Charlotte K.Y. Ng Humanitas University
Salvatore Piscuoglio
Salvatore Piscuoglio Humanitas University

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