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Hiroyasu Nakano

Hiroyasu Nakano

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
36721
World Ranking
6495
National Ranking
423

Overview

Hiroyasu Nakano is affiliated with Toho University in Japan and has contributed extensively to research within the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Their publication record includes a strong focus on Molecular Biology, Immunology, Oncology, Cardiology and Cardiovascular Medicine, and Epidemiology.

The scientist's research primarily addresses topics such as cell death mechanisms and regulation, immune cell function and interaction, fibroblast growth factor research, cytokine signaling pathways and interactions, interferon and immune responses, trace elements in health, and liver disease diagnosis and treatment. These topics reflect a broad scope within biomedical research, integrating molecular and cellular perspectives.

Hiroyasu Nakano's body of work includes several notable papers, such as:

  • Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer, 2021, Nature Communications
  • A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction, 2020, Nature Communications
  • Identification of the hallmarks of necroptosis and ferroptosis by transmission electron microscopy, 2020, Biochemical and Biophysical Research Communications
  • Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy, 2020, Nature Communications
  • Regulation of T cell differentiation by the AP-1 transcription factor JunB, 2021, Immunological Medicine

Frequent publication venues for this researcher include Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Biochemical and Biophysical Research Communications, Communications Biology, and iScience. These outlets indicate an active engagement with both peer-reviewed journals and preprint platforms.

Collaborative work is common in their research activities, with frequent co-authors including Sachiko Komazawa-Sakon, Kenta Moriwaki, Takashi Nishina, Tetuo Mikami, and Soh Yamazaki. These associations suggest involvement in broad research networks and interdisciplinary projects.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • ASK1 Is Essential for JNK/SAPK Activation by TRAF2

    Hideki Nishitoh;Masao Saitoh;Masao Saitoh;Yoshiyuki Mochida;Yoshiyuki Mochida;Kohsuke Takeda;Kohsuke Takeda

  • Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

    Hiroyasu Nakano;Masahisa Shindo;Sachiko Sakon;Shigeyuki Nishinaka

  • SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

    Fuminori Tokunaga;Tomoko Nakagawa;Masaki Nakahara;Yasushi Saeki

  • NF‐κB inhibits TNF‐induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

    Sachiko Sakon;Xin Xue;Mutsuhiro Takekawa;Mutsuhiro Takekawa;Tomonari Sasazuki

  • A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-κB activation

    Mizuho Hasegawa;Yukari Fujimoto;Peter C Lucas;Hiroyasu Nakano

  • The atypical PKC‐interacting protein p62 channels NF‐κB activation by the IL‐1–TRAF6 pathway

    Laura Sanz;María T. Diaz‐Meco;Hiroyasu Nakano;Jorge Moscat

  • NF-κB RelA Phosphorylation Regulates RelA Acetylation

    Lin Feng Chen;Samuel A. Williams;Yajun Mu;Hiroyasu Nakano

  • Tumor Necrosis Factor-α-induced IKK Phosphorylation of NF-κB p65 on Serine 536 Is Mediated through the TRAF2, TRAF5, and TAK1 Signaling Pathway

    Hiroaki Sakurai;Shunsuke Suzuki;Noritaka Kawasaki;Hiroyasu Nakano;Hiroyasu Nakano

  • Tumor Necrosis Factor α (TNFα) Induces the Unfolded Protein Response (UPR) in a Reactive Oxygen Species (ROS)-dependent Fashion, and the UPR Counteracts ROS Accumulation by TNFα

    Xin Xue;Jiang-Hu Piao;Akihito Nakajima;Sachiko Sakon-Komazawa

  • Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis.

    Nacksung Kim;Yuho Kadono;Masamichi Takami;Junwon Lee

  • Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.

    Nakano H;Nakajima A;Sakon-Komazawa S;Piao Jh

  • TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

    Hiroyasu Nakano;Hideo Oshima;Winston Chung;Laura Williams-Abbott

  • TWEAK Induces NF-κB2 p100 Processing and Long Lasting NF-κB Activation

    Tatsuya Saitoh;Masafumi Nakayama;Hiroyasu Nakano;Hideo Yagita

  • Critical Roles of TRAF2 and TRAF5 in Tumor Necrosis Factor-induced NF-κB Activation and Protection from Cell Death

    Kurisu Tada;Tatsuma Okazaki;Sachiko Sakon;Tomonari Kobarai

  • Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis.

    Shinya Tsurusaki;Yuichi Tsuchiya;Tomoko Koumura;Misaki Nakasone

  • CD27, a Member of the Tumor Necrosis Factor Receptor Superfamily, Activates NF-κB and Stress-activated Protein Kinase/c-Jun N-terminal Kinase via TRAF2, TRAF5, and NF-κB-inducing Kinase *

    Hisaya Akiba;Hiroyasu Nakano;Shigeyuki Nishinaka;Masahisa Shindo

  • Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I

    Akemi Matsushima;Tsuneyasu Kaisho;Paul D. Rennert;Hiroyasu Nakano

Frequent Co-Authors

Ko Okumura
Ko Okumura Juntendo University
Hideo Yagita
Hideo Yagita Juntendo University
Yasuo Uchiyama
Yasuo Uchiyama Juntendo University
Masato Koike
Masato Koike Juntendo University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Andras Kapus
Andras Kapus University of Toronto
Naohiro Inohara
Naohiro Inohara University of Michigan–Ann Arbor
Jun-ichiro Inoue
Jun-ichiro Inoue University of Tokyo
Sergio Lavandero
Sergio Lavandero University of Chile
Shazib Pervaiz
Shazib Pervaiz National University of Singapore

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