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Biology and Biochemistry

D-Index
82
Citations
39799
World Ranking
3613
National Ranking
24

Overview

Juergen A. Knoblich is affiliated with the Austrian Academy of Sciences in Austria. Their research primarily spans the domain of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology specifically. Additional subfields include Oncology, Biomedical Engineering, Cancer Research, and Pulmonary and Respiratory Medicine.

The main topics Juergen A. Knoblich has worked on include:

  • Pluripotent Stem Cells Research
  • Single-cell and spatial transcriptomics
  • CRISPR and Genetic Engineering
  • Renal and related cancers
  • RNA regulation and disease
  • RNA Research and Splicing
  • Neurogenesis and neuroplasticity mechanisms

The scientist has published in a number of high-profile journals and platforms. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Stem Cell Reports
  • The EMBO Journal
  • Annals of Oncology

Recent papers include the following contributions:

  • "Human organoids: model systems for human biology and medicine," 2020, Nature Reviews Molecular Cell Biology
  • "ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update," 2021, Stem Cell Reports
  • "Human cerebral organoids - a new tool for clinical neurology research," 2022, Nature Reviews Neurology
  • "A nomenclature consensus for nervous system organoids and assembloids," 2022, Nature
  • "Single-cell brain organoid screening identifies developmental defects in autism," 2023, Nature

Juergen A. Knoblich has collaborated frequently with several researchers, including:

  • Christopher Esk
  • Maria Novatchkova
  • Nina S. Corsini
  • Angela Maria Peer
  • Ábel Vértesy

Best Publications

  • Cerebral organoids model human brain development and microcephaly

    Madeline A. Lancaster;Magdalena Renner;Carol Anne Martin;Daniel Wenzel

  • Organogenesis in a dish: modeling development and disease using organoid technologies.

    Madeline A. Lancaster;Juergen A. Knoblich

  • Human organoids: model systems for human biology and medicine.

    Jihoon Kim;Bon-Kyoung Koo;Juergen A. Knoblich;Juergen A. Knoblich

  • Generation of cerebral organoids from human pluripotent stem cells

    Madeline A Lancaster;Juergen A Knoblich

  • Mechanisms of Asymmetric Stem Cell Division

    Juergen A. Knoblich

  • Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

    J. Gray Camp;Farhath Badsha;Marta Florio;Sabina Kanton

  • The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

    Jörg Betschinger;Karl Mechtler;Juergen A. Knoblich

  • Guided self-organization and cortical plate formation in human brain organoids

    Madeline A Lancaster;Madeline A Lancaster;Nina S Corsini;Simone Wolfinger;E Hilary Gustafson

  • Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

    Juergen A. Knoblich;Karsten Sauer;Lynn M. Jones;Helena E. Richardson

  • Fused cerebral organoids model interactions between brain regions

    Joshua A Bagley;Daniel Reumann;Shan Bian;Julie Lévi-Strauss

  • Asymmetric cell division: recent developments and their implications for tumour biology

    Juergen A. Knoblich

  • Human blood vessel organoids as a model of diabetic vasculopathy

    Reiner A. Wimmer;Alexandra Leopoldi;Martin Aichinger;Nikolaus Wick

  • Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells

    Joerg Betschinger;Karl Mechtler;Karl Mechtler;Juergen A. Knoblich

  • Dare to Be Different: Asymmetric Cell Division in Drosophila, C. elegans and Vertebrates

    Jörg Betschinger;Jürgen A. Knoblich

  • Asymmetric segregation of Numb and Prospero during cell division

    J. A. Knoblich;L. Y. Jan;Yuh Nung Jan

  • Drosophila neuroblasts: a model for stem cell biology.

    Catarina C. F. Homem;Juergen A. Knoblich

  • Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer

    Ralph A. Neumüller;Juergen A. Knoblich

  • DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila.

    Mark Petronczki;Juergen A. Knoblich

  • The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

    Jens Christian Schwamborn;Eugene Berezikov;Juergen A. Knoblich

  • The Endocytic Protein α-Adaptin Is Required for Numb-Mediated Asymmetric Cell Division in Drosophila

    Daniela Berdnik;Tibor Török;Marcos González-Gaitán;Juergen A. Knoblich

Frequent Co-Authors

Maria Novatchkova
Maria Novatchkova University of Vienna
Karl Mechtler
Karl Mechtler Research Institute of Molecular Pathology
Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
Heinrich Reichert
Heinrich Reichert University of Basel
Josef M. Penninger
Josef M. Penninger University of British Columbia
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Hugo J. Bellen
Hugo J. Bellen Baylor College of Medicine
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Aviv Regev
Aviv Regev Genentech

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