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Barbara Treutlein

Barbara Treutlein

D-Index & Metrics

Molecular Biology

D-Index
43
Citations
12694
World Ranking
2949
National Ranking
54

Overview

Barbara Treutlein is a researcher affiliated with ETH Zurich in Switzerland, specializing in biochemistry, genetics, and molecular biology. The majority of their work focuses on molecular biology, with additional contributions in oncology, biophysics, genetics, and cancer research.

The scientist's prominent research topics include single-cell and spatial transcriptomics, pluripotent stem cells research, cell image analysis techniques, CRISPR and genetic engineering, cancer cells and metastasis, gene regulatory network analysis, and cancer genomics and diagnostics.

Frequent co-authors collaborating with Barbara Treutlein include J. Gray Camp, Zhisong He, Małgorzata Santel, Jonas Simon Fleck, and Makiko Seimiya.

Barbara Treutlein has published extensively in a variety of scientific venues. These venues include bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature, Science, and Nature Communications.

Selected recent papers authored or co-authored by Barbara Treutlein are:

  • Inferring and perturbing cell fate regulomes in human brain organoids, 2022, Nature
  • A nomenclature consensus for nervous system organoids and assembloids, 2022, Nature
  • Single-cell brain organoid screening identifies developmental defects in autism, 2023, Nature
  • The road ahead in genetics and genomics, 2020, Nature Reviews Genetics
  • Lineage recording in human cerebral organoids, 2021, Nature Methods

Best Publications

  • Reconstructing lineage hierarchies of the distal lung epithelium using single cell RNA-seq

    Barbara Treutlein;Doug G. Brownfield;Angela Ruohao Wu;Norma F. Neff

  • Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

    J. Gray Camp;Farhath Badsha;Marta Florio;Sabina Kanton

  • Quantitative assessment of single-cell RNA-sequencing methods

    Angela Ruohao Wu;Norma F. Neff;Tomer Kalisky;Piero Dalerba

  • Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

    Andrew E. Vaughan;Alexis N. Brumwell;Ying Xi;Jeffrey E. Gotts

  • Organoid single-cell genomic atlas uncovers human-specific features of brain development

    Sabina Kanton;Michael James Boyle;Zhisong He;Zhisong He;Malgorzata Santel

  • Multilineage communication regulates human liver bud development from pluripotency

    J Gray Camp;Keisuke Sekine;Tobias Gerber;Henry Loeffler-Wirth

  • Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq

    Barbara Treutlein;Qian Yi Lee;J. Gray Camp;Moritz Mall

  • Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq

    Ozgun Gokce;Ozgun Gokce;Geoffrey M. Stanley;Barbara Treutlein;Norma F. Neff

  • Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

    Tobias Gerber;Prayag Murawala;Prayag Murawala;Dunja Knapp;Wouter Masselink

  • Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing

    Barbara Treutlein;Ozgun Gokce;Stephen R. Quake;Thomas C. Südhof

  • Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

    Jared M. Churko;Priyanka Garg;Priyanka Garg;Barbara Treutlein;Meenakshi Venkatasubramanian

  • The road ahead in genetics and genomics.

    Amy L. McGuire;Stacey Gabriel;Sarah A. Tishkoff;Ambroise Wonkam

  • Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia

    Johannes Klaus;Sabina Kanton;Christina Kyrousi;Ane Cristina Ayo-Martin

  • A roadmap for the Human Developmental Cell Atlas

    Muzlifah Haniffa;Muzlifah Haniffa;Deanne Taylor;Deanne Taylor;Sten Linnarsson;Bruce J. Aronow

  • In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution.

    Alyssa J. Miller;Qianhui Yu;Qianhui Yu;Michael Czerwinski;Yu-Hwai Tsai

  • Mapping Development of the Human Intestinal Niche at Single-Cell Resolution.

    Emily M. Holloway;Michael Czerwinski;Yu-Hwai Tsai;Joshua H. Wu

  • Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons

    Orly L. Wapinski;Qian Yi Lee;Albert C. Chen;Rui Li

  • Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains.

    Ekaterina Khrameeva;Ilia Kurochkin;Dingding Han;Patricia Guijarro

  • The Organoid Cell Atlas.

    Christoph Bock;Christoph Bock;Michael Boutros;J. Gray Camp;Laura Clarke

  • Charting human development using a multi-endodermal organ atlas and organoid models

    Qianhui Yu;Umut Kilik;Emily M. Holloway;Yu-Hwai Tsai

Frequent Co-Authors

Stephen R. Quake
Stephen R. Quake Stanford University
Svante Pääbo
Svante Pääbo Max Planck Institute for Evolutionary Anthropology
Jason R. Spence
Jason R. Spence University of Michigan–Ann Arbor
Ian A. Glass
Ian A. Glass University of Washington
Aviv Regev
Aviv Regev Genentech
Philipp Khaitovich
Philipp Khaitovich Skolkovo Institute of Science and Technology
Wieland B. Huttner
Wieland B. Huttner Max Planck Society
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Patrick Cramer
Patrick Cramer Max Planck Society
Thomas C. Südhof
Thomas C. Südhof Stanford University

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