Peter W. Piper

Overview

Best Publications

• Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

  Chrisostomos Prodromou;S. Mark Roe;Ronan O'Brien;John Edward Simon Durham Ladbury

  1636
  Citations

• Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

  S M Roe;C Prodromou;R O'Brien;J E Ladbury

  1227
  Citations

• Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex

  Maruf M. U. Ali;S. Mark Roe;Cara K. Vaughan;Phillipe Meyer;Phillipe Meyer

  1141
  Citations

• ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

  Barry Panaretou;Chrisostomos Prodromou;S. Mark Roe;Ronan O'Brien

  936
  Citations

• The ATPase cycle of Hsp90 drives a molecular ‘clamp’ via transient dimerization of the N-terminal domains

  Chrisostomos Prodromou;Barry Panaretou;Barry Panaretou;Shahzad Chohan;Giuliano Siligardi

  651
  Citations

• Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.

  Barry Panaretou;Giuliano Siligardi;Philippe Meyer;Alison Maloney

  632
  Citations

• Structural and Functional Analysis of the Middle Segment of Hsp90 Implications for ATP Hydrolysis and Client Protein and Cochaperone Interactions

  Philippe Meyer;Chrisostomos Prodromou;Bin Hu;Cara Vaughan

  589
  Citations

• Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones

  Chrisostomos Prodromou;Giuliano Siligardi;Ronan O'Brien;Derek N. Woolfson

  554
  Citations

• The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap

  Peter W. Piper

  552
  Citations

• Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives

  Peter Piper;Claudia Ortiz Calderon;T. Kostas Hatzixanthis;Mehdi Mollapour

  457
  Citations

• The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast

  Peter Piper;Yannick Mahé;Suzanne Thompson;Rudy Pandjaitan

  428
  Citations

• The mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)

  S.Mark Roe;Maruf M.U Ali;Philippe Meyer;Cara K Vaughan

  426
  Citations

• Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.

  Philippe Meyer;Chrisostomos Prodromou;Chunyan Liao;Bin Hu

  389
  Citations

• The molecular defences against reactive oxygen species in yeast

  P. Moradas-Ferreira;V. Costa;P. Piper;W.H. Mager

  371
  Citations

• Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37.

  Giuliano Siligardi;Barry Panaretou;Philippe Meyer;Shradha Singh

  337
  Citations

• Molecular events associated with acquisition of heat tolerance by the yeast Saccharomyces cerevisiae

  Peter W. Piper

  316
  Citations

• Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid.

  Mehdi Mollapour;Peter W. Piper

  311
  Citations

• A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone

  C Prodromou;S.M Roe;P.W Piper;L.H. Pearl

  289
  Citations

• Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle.

  Giuliano Siligardi;Bin Hu;Barry Panaretou;Peter W. Piper

  247
  Citations

• Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37

  Cara K. Vaughan;Mehdi Mollapour;Jennifer R. Smith;Andrew W. Truman

  242
  Citations