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S. Mark Roe

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
18180
World Ranking
19032
National Ranking
1481

S. Mark Roe publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where S. Mark Roe sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 164 publications — 34th percentile

34% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

S. Mark Roe D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where S. Mark Roe sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 45 D-Index — 3rd percentile

3% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

S. Mark Roe is affiliated with the University of Sussex in the United Kingdom. Their research spans materials science and biochemistry, genetics, and molecular biology, with a focus on materials chemistry, molecular biology, organic chemistry, oncology, and biochemistry.

The scientist has contributed extensively to the understanding of crystallization and solubility studies, X-ray diffraction in crystallography, metal complexes synthesis and properties, enzyme structure and function, DNA repair mechanisms, DNA and nucleic acid chemistry, and amino acid enzymes and metabolism.

Roe's publication record includes the following recent papers:

  • The structure-function relationship of oncogenic LMTK3, 2020, Science Advances
  • Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction, 2022, Organic Letters
  • Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein, 2021, eLife
  • The role of both intercalation and groove binding at AT-rich DNA regions in the interaction process of a dinuclear Cu(I) complex probed by spectroscopic and simulation analysis, 2021, Journal of Molecular Liquids
  • Exotic Electronic Properties of 2D Nanosheets Isolated from Liquid Phase Exfoliated Phyllosilicate Minerals, 2023, Advanced Materials

Frequent coauthors working alongside Roe include:

  • Khodayar Gholivand
  • Neda Choodari Milani
  • Yazdan Maghsoud
  • Mahdieh Hosseini
  • Abouzar Babaei

Roe has published frequently in these venues:

  • The Cambridge Structural Database (10 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • ChemistrySelect (3 publications)
  • Organic Letters (1 publication)
  • Science Advances (1 publication)

Their expertise involves combining experimental and computational methods to explore molecular structures and interactions, contributing to both materials chemistry and molecular biology. This multidisciplinary approach allows exploration of enzyme function, DNA interactions, and the synthesis and characterization of novel materials.

Best Publications

  • Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf

    Paul T.C Wan;Mathew J Garnett;S.Mark Roe;Sharlene Lee

  • Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

    Chrisostomos Prodromou;S. Mark Roe;Ronan O'Brien;John Edward Simon Durham Ladbury

  • Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

    S M Roe;C Prodromou;R O'Brien;J E Ladbury

  • Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex

    Maruf M. U. Ali;S. Mark Roe;Cara K. Vaughan;Phillipe Meyer;Phillipe Meyer

  • GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

    Laurent Meijer;Alexios-Leandros Skaltsounis;Prokopios Magiatis;Panagiotis Polychronopoulos

  • ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

    Barry Panaretou;Chrisostomos Prodromou;S. Mark Roe;Ronan O'Brien

  • Crystal Structure of Glycogen Synthase Kinase 3β: Structural Basis for Phosphate-Primed Substrate Specificity and Autoinhibition

    Rana Dajani;Elizabeth Fraser;S. Mark Roe;Neville Young

  • Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex.

    James S. Parker;S. Mark Roe;David Barford

  • The ATPase cycle of Hsp90 drives a molecular ‘clamp’ via transient dimerization of the N-terminal domains

    Chrisostomos Prodromou;Barry Panaretou;Barry Panaretou;Shahzad Chohan;Giuliano Siligardi

  • Structural and Functional Analysis of the Middle Segment of Hsp90 Implications for ATP Hydrolysis and Client Protein and Cochaperone Interactions

    Philippe Meyer;Chrisostomos Prodromou;Bin Hu;Cara Vaughan

  • Chaperoned Ubiquitylation-Crystal Structures of the Chip U Box E3 Ubiquitin Ligase and a Chip-Ubc13-Uev1A Complex

    Minghao Zhang;Mark Windheim;S. Mark Roe;Mark Peggie

  • Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity

    James S Parker;S Mark Roe;David Barford

  • Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

    Rana Dajani;Elizabeth Fraser;S. Mark Roe;Margaret Yeo

  • The mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)

    S.Mark Roe;Maruf M.U Ali;Philippe Meyer;Cara K Vaughan

  • Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.

    Philippe Meyer;Chrisostomos Prodromou;Chunyan Liao;Bin Hu

  • Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the β-clamp

    Karen A. Bunting;S.Mark Roe;Laurence H. Pearl

  • Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

    Stacey M. Southall;Poon-Sheng Wong;Zain Odho;S. Mark Roe

  • A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone

    C Prodromou;S.M Roe;P.W Piper;L.H. Pearl

  • The Identification, Synthesis, Protein Crystal Structure and in Vitro Biochemical Evaluation of a New 3,4-Diarylpyrazole Class of Hsp90 Inhibitors.

    Kwai-Ming J. Cheung;Thomas P. Matthews;Karen James;Martin G. Rowlands

  • Molecular basis for TPR domain‐mediated regulation of protein phosphatase 5

    Jing Yang;S. Mark Roe;Matthew J. Cliff;Mark A. Williams

Frequent Co-Authors

Laurence H. Pearl
Laurence H. Pearl University of Sussex
Chrisostomos Prodromou
Chrisostomos Prodromou University of Sussex
F. Geoffrey N. Cloke
F. Geoffrey N. Cloke University of Sussex
Peter W. Piper
Peter W. Piper University of Sheffield
Paul Workman
Paul Workman Institute of Cancer Research
David Barford
David Barford MRC Laboratory of Molecular Biology
Christopher J. Moody
Christopher J. Moody University of Nottingham
John E. Ladbury
John E. Ladbury University of Leeds
John R. Atack
John R. Atack Cardiff University
William Lewis
William Lewis University of Sydney

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Each option offers flexible study, perfect for busy professionals or students seeking remote learning. Pursuing these specialized online degrees is an effective way to align your education in biology or biochemistry with targeted career advancement in today’s evolving job market.

Best Scientists Citing S. Mark Roe

Paul Workman

Paul Workman

Institute of Cancer Research

Publications: 85

Johannes Buchner

Johannes Buchner

Technical University of Munich

Publications: 77

Laurence H. Pearl

Laurence H. Pearl

University of Sussex

Publications: 72

Chrisostomos Prodromou

Chrisostomos Prodromou

University of Sussex

Publications: 66

Leonard M. Neckers

Leonard M. Neckers

National Institutes of Health

Publications: 57

Neal Rosen

Neal Rosen

Memorial Sloan Kettering Cancer Center

Publications: 45

Richard Marais

Richard Marais

University of Manchester

Publications: 43

David A. Agard

David A. Agard

University of California, San Francisco

Publications: 38

Gabriela Chiosis

Gabriela Chiosis

Memorial Sloan Kettering Cancer Center

Publications: 33

Keith T. Flaherty

Keith T. Flaherty

Harvard University

Publications: 31

Laurent Meijer

Laurent Meijer

Perha Pharmaceuticals

Publications: 31

David B. Solit

David B. Solit

Memorial Sloan Kettering Cancer Center

Publications: 30

Vladimir N. Uversky

Vladimir N. Uversky

University of South Florida

Publications: 27

Stefan Knapp

Stefan Knapp

Goethe University Frankfurt

Publications: 26

Peter W. Piper

Peter W. Piper

University of Sheffield

Publications: 26

Brian S. J. Blagg

Brian S. J. Blagg

University of Notre Dame

Publications: 25

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