World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
10046
World Ranking
16660
National Ranking
6890

Overview

James B. Konopka is affiliated with Stony Brook University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans several subfields including molecular biology, infectious diseases, cell biology, epidemiology, and plant science.

Their research focuses on topics such as antifungal resistance and susceptibility, fungal and yeast genetics research, fungal infections and studies, cellular transport and secretion, plant-microbe interactions and immunity, endoplasmic reticulum stress and disease, and neutrophil, myeloperoxidase, and oxidative mechanisms.

Recent publications by Konopka include:

  • Plasma Membrane MCC/Eisosome Domains Promote Stress Resistance in Fungi, 2020, Microbiology and Molecular Biology Reviews
  • Fungal Pathogens: Shape-Shifting Invaders, 2020, Trends in Microbiology
  • Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in Candida albicans, 2021, PLoS Pathogens
  • Microdomain Protein Nce102 Is a Local Sensor of Plasma Membrane Sphingolipid Balance, 2022, Microbiology Spectrum
  • A Conserved Machinery Underlies the Synthesis of a Chitosan Layer in the Candida Chlamydospore Cell Wall, 2021, mSphere

Konopka frequently collaborates with several researchers, among them Kyunghun Min, Carla E. Lanze, Rafael M. Gandra, Kara A. Swenson, and Lois M. Douglas.

They have published repeatedly in venues such as bioRxiv (Cold Spring Harbor Laboratory), mSphere, Microbiology and Molecular Biology Reviews, mBio, and Trends in Microbiology.

Best Publications

  • An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

    James B. Konopka;Susan M. Watanabe;Owen N. Witte

  • N-Acetylglucosamine Functions in Cell Signaling

    James B. Konopka

  • Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration

    James B. Konopka;Susan M. Watanabe;Jack W. Singer;Steven J. Collins

  • Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.

    J B Konopka;O N Witte

  • Lipid raft polarization contributes to hyphal growth in Candida albicans.

    Stephen W. Martin;James B. Konopka

  • Two new S-phase-specific genes from Saccharomyces cerevisiae.

    Siyuan Le;Colleen Davis;James B. Konopka;Rolf Sternglanz

  • Conjugation in Saccharomyces cerevisiae.

    Fred Cross;Leland H. Hartwell;Catherine Jackson;James B. Konopka

  • The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone

    James B. Konopka;Duane D. Jenness;Leland H. Hartwell

  • Septin Function in Candida albicans Morphogenesis

    Amy J. Warenda;James B. Konopka

  • DEP-Domain-Mediated Regulation of GPCR Signaling Responses

    Daniel R. Ballon;Paul L. Flanary;Douglas P. Gladue;James B. Konopka

  • Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties.

    R L Davis;J B Konopka;O N Witte

  • Sterol-Rich Plasma Membrane Domains in Fungi

    Francisco J. Alvarez;Lois M. Douglas;James B. Konopka

  • S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination

    Catherine L. Jackson;James B. Konopka;Leland H. Hartwell

  • Identification of an N-acetylglucosamine transporter that mediates hyphal induction in Candida albicans.

    Francisco J. Alvarez;James B. Konopka

  • Fungal membrane organization: the eisosome concept.

    Lois M Douglas;James B Konopka

  • Septin function in yeast model systems and pathogenic fungi.

    Lois M. Douglas;Francisco J. Alvarez;Cheryl McCreary;James B. Konopka

  • Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor

    James B. Konopka;Steluta Mariana Margarit;Peter Dube

  • Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity.

    J B Konopka;R L Davis;S M Watanabe;A S Ponticelli

  • Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

    Visesato Mor;Antonella Rella;Amir M. Farnoud;Ashutosh Singh

  • Candida albicans septin mutants are defective for invasive growth and virulence.

    Amy J. Warenda;Sarah Kauffman;Taylor P. Sherrill;Jeffrey M. Becker

Frequent Co-Authors

Owen N. Witte
Owen N. Witte University of California, Los Angeles
Marcio L. Rodrigues
Marcio L. Rodrigues Federal University of Rio de Janeiro
Aaron M. Neiman
Aaron M. Neiman Stony Brook University
Malcolm Whiteway
Malcolm Whiteway Concordia University
Melanie T. Cushion
Melanie T. Cushion University of Cincinnati Medical Center
Leland H. Hartwell
Leland H. Hartwell Arizona State University
Uta Paszkowski
Uta Paszkowski University of Cambridge
Guri Giaever
Guri Giaever University of British Columbia
Corey Nislow
Corey Nislow University of British Columbia
Stanley Fields
Stanley Fields University of Washington

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