World's Best Scientists 2026 revealed!
Amy S. Gladfelter

Amy S. Gladfelter

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
13455
World Ranking
15988
National Ranking
6639

Overview

Amy S. Gladfelter is affiliated with Duke University in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, focusing intensively on Molecular Biology and aspects of Cell Biology, Plant Science, and Ecology.

The main topics of their work include:

  • RNA Research and Splicing
  • Fungal and yeast genetics research
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Photosynthetic Processes and Mechanisms
  • Plant Reproductive Biology
  • Microbial Metabolic Engineering and Bioproduction

They have authored research papers published in several frequently accessed scientific venues. The key venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • UNC Libraries
  • Current Biology
  • The Journal of Cell Biology

Some of their recent notable publications are:

  • "RNA contributions to the form and function of biomolecular condensates," 2020, Nature Reviews Molecular Cell Biology
  • "Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid," 2020, Molecular Cell
  • "HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells," 2021, Science
  • "Membrane surfaces regulate assembly of ribonucleoprotein condensates," 2022, Nature Cell Biology
  • "The state of the septin cytoskeleton from assembly to function," 2020, Current Opinion in Cell Biology

They collaborate frequently with a group of scientists, among whom the most frequent co-authors are:

  • Ian Seim
  • Christine Roden
  • Joanne Ekena
  • Ameya P. Jalihal
  • Grace A. McLaughlin

Amy S. Gladfelter's research addresses complex cellular processes, with a particular focus on the molecular mechanisms involving RNA and protein interactions, phase separation phenomena, and cellular compartmentalization. Their work contributes to specialized knowledge in fungal and yeast genetics, as well as the molecular biology underpinning RNA function and modifications related to disease contexts such as cancer.

Best Publications

  • Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates.

    Simon Alberti;Simon Alberti;Amy Gladfelter;Amy Gladfelter;Tanja Mittag

  • RNA Controls PolyQ Protein Phase Transitions

    Huaiying Zhang;Shana Elbaum-Garfinkle;Erin M. Langdon;Nicole Taylor

  • mRNA structure determines specificity of a polyQ-driven phase separation

    Erin M. Langdon;Yupeng Qiu;Amirhossein Ghanbari Niaki;Grace A. McLaughlin

  • RNA contributions to the form and function of biomolecular condensates.

    Christine Roden;Amy S. Gladfelter;Amy S. Gladfelter

  • The septin cortex at the yeast mother-bud neck.

    Amy S Gladfelter;John R Pringle;Daniel J Lew

  • Genomic Rna Elements Drive Phase Separation of the Sars-Cov-2 Nucleocapsid

    Christiane Iserman;Christine A. Roden;Mark A. Boerneke;Rachel S.G. Sealfon

  • Scaffold-mediated symmetry breaking by Cdc42p.

    Javier E. Irazoqui;Amy S. Gladfelter;Daniel J. Lew

  • Fungi in the Marine Environment: Open Questions and Unsolved Problems.

    Anthony Amend;Gaetan Burgaud;Michael Cunliffe;Virginia P. Edgcomb

  • The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation

    Wilton T. Snead;Amy S. Gladfelter;Amy S. Gladfelter

  • HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells

    Haiyang Yu;Shan Lu;Kelsey Gasior;Digvijay Singh

  • Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p.

    Amy S. Gladfelter;Indrani Bose;Trevin R. Zyla;Elaine S.G. Bardes

  • Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton

    Andrew A. Bridges;Andrew A. Bridges;Maximilian S. Jentzsch;Patrick W. Oakes;Patricia Occhipinti

  • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud

    Joan E. Adamo;John J. Moskow;Amy S. Gladfelter;Domenic Viterbo

  • Non-model model organisms.

    James J Russell;Julie A Theriot;Pranidhi Sood;Wallace F Marshall

  • Cytoskeletal dynamics: a view from the membrane.

    Magdalena Bezanilla;Amy S. Gladfelter;David R. Kovar;Wei-Lih Lee

  • Septin assemblies form by diffusion-driven annealing on membranes

    Andrew A. Bridges;Huaiying Zhang;Huaiying Zhang;Shalin B. Mehta;Patricia Occhipinti

  • Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora

    Chen-Hui Chen;Bradley S. DeMay;Amy S. Gladfelter;Jay C. Dunlap

  • Septin Form and Function at the Cell Cortex

    Andrew A. Bridges;Amy S. Gladfelter

  • A New Lens for RNA Localization: Liquid-Liquid Phase Separation

    Erin M Langdon;Amy S Gladfelter;Amy S Gladfelter

  • Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid

    Christiane Iserman;Christine Anne Roden;Mark A. Boerneke;Rachel Sealfon

Frequent Co-Authors

Daniel J. Lew
Daniel J. Lew Duke University
Kevin M. Weeks
Kevin M. Weeks University of North Carolina at Chapel Hill
Jay C. Dunlap
Jay C. Dunlap Dartmouth College
Olga G. Troyanskaya
Olga G. Troyanskaya Princeton University
Jennifer J. Loros
Jennifer J. Loros Dartmouth College
Paul A. Anderson
Paul A. Anderson University of Wisconsin–Madison
Mark Peifer
Mark Peifer University of North Carolina at Chapel Hill
Timothy P. Sheahan
Timothy P. Sheahan University of North Carolina at Chapel Hill
Bob Goldstein
Bob Goldstein University of North Carolina at Chapel Hill
Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill

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