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François M. Vallette

François M. Vallette

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
23815
World Ranking
8961
National Ranking
316

Overview

François M. Vallette is affiliated with Inserm in France, where their research primarily spans the domains of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work covers significant subfields including Molecular Biology, Oncology, Cancer Research, Genetics, and Immunology.

The scientist's research focuses on a number of key topics related to cancer biology and treatment such as Cancer Cells and Metastasis, Glioma Diagnosis and Treatment, 3D Printing in Biomedical Research, MicroRNA in disease regulation, Immune cells in cancer, Cellular Mechanics and Interactions, and Extracellular vesicles in disease.

Vallette has contributed to several publications in well-regarded scientific venues. The frequent publication outlets include:

  • Cancers
  • Cell Death and Disease
  • Trends in cancer
  • Molecular Cancer
  • Epigenomics

The scientist has authored or co-authored a variety of papers addressing the molecular and cellular challenges in oncology, particularly glioblastoma and drug resistance. Noteworthy recent papers include:

  • Challenges in glioblastoma research: focus on the tumor microenvironment, 2022, Trends in cancer
  • Three-dimensional in vitro culture models in oncology research, 2022, Cell & Bioscience
  • Drug Resistance in Glioblastoma: The Two Faces of Oxidative Stress, 2021, Frontiers in Molecular Biosciences
  • Drug-tolerant persister cells in cancer: the cutting edges and future directions, 2023, Nature Reviews Clinical Oncology
  • Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme, 2020, Molecular Cancer

Their collaborations include frequent co-authorship with:

  • Lisa Oliver
  • Dominique Heymann
  • Pierre-François Cartron
  • Joséphine Briand
  • Catherine Gratas

François M. Vallette's publication record illustrates a strong emphasis on molecular mechanisms underlying cancer progression and treatment resistance, with a focus on glioma pathologies. The diversity of topics such as microRNA regulation and extracellular vesicle roles reflects multidisciplinary approaches integrating molecular biology and clinical implications.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular and cellular biology of cholinesterases

    Jean Massoulié;Leo Pezzementi;Suzanne Bon;Eric Krejci

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The mitochondrial pathways of apoptosis.

    Jérome Estaquier;François Vallette;Jean-Luc Vayssiere;Bernard Mignotte

  • Bax activation and mitochondrial insertion during apoptosis.

    Lisenn Lalier;Pierre-François Cartron;Pierre-François Cartron;Philippe Juin;Philippe Juin;Svetlana Nedelkina

  • Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils

    Anne-Laure Genestier;Marie-Cécile Michallet;Gilles Prévost;Gregory Bellot

  • Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast

    M Priault;B Salin;J Schaeffer;F M Vallette

  • The First α Helix of Bax Plays a Necessary Role in Its Ligand-Induced Activation by the BH3-Only Proteins Bid and PUMA

    Pierre-François Cartron;Tristan Gallenne;Gwenola Bougras;Fabien Gautier

  • Construction of mutant and chimeric genes using the polymerase chain reaction

    Francois Vallette;Emmanuelle Mege;Allison Reiss;Milton Adesnik

  • Mitochondria as the target of the pro-apoptotic protein Bax.

    Emine Er;Lisa Oliver;Pierre-François Cartron;Philippe Juin

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation.

    Eric Hervouet;François M Vallette;Pierre-François Cartron

  • Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods

    Lucie Karayan-Tapon;Véronique Quillien;Joëlle Guilhot;Michel Wager

  • TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax

    Bellot G;Bellot G;Cartron Pf;Cartron Pf;Er E;Er E;Oliver L;Oliver L

  • Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

    Tristan Gallenne;Fabien Gautier;Fabien Gautier;Lisa Oliver;Lisa Oliver;Eric Hervouet;Eric Hervouet

  • Influence of oxygen tension on CD133 phenotype in human glioma cell cultures.

    Nadine Platet;Shi Yong Liu;Michèle El Atifi;Lisa Oliver

  • Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer.

    François M. Vallette;Christophe Olivier;Frédéric Lézot;Lisa Oliver

  • The Small Organic Compound HA14-1 Prevents Bcl-2 Interaction with Bax to Sensitize Malignant Glioma Cells to Induction of Cell Death

    Florence Manero;Fabien Gautier;Tristan Gallenne;Nicolas Cauquil

  • An anti-apoptotic viral protein that recruits Bax to mitochondria.

    Delphine Poncet;Nathanael Larochette;Anne-Laure Pauleau;Patricia Boya

  • Disruption of Dnmt1/PCNA/UHRF1 Interactions Promotes Tumorigenesis from Human and Mice Glial Cells

    Eric Hervouet;Lisenn Lalier;Lisenn Lalier;Emilie Debien;Emilie Debien;Mathilde Cheray;Mathilde Cheray

Frequent Co-Authors

Lisa Oliver
Lisa Oliver University of Nantes
Dominique Heymann
Dominique Heymann University of Nantes
Stéphen Manon
Stéphen Manon University of Bordeaux
Julie Gavard
Julie Gavard University of Nantes
Evelina Gatti
Evelina Gatti Aix-Marseille University
Jean Massoulié
Jean Massoulié École Normale Supérieure
Emmanuel Scotet
Emmanuel Scotet University of Nantes
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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