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Biology and Biochemistry

D-Index
48
Citations
17031
World Ranking
18192
National Ranking
822

Overview

Stéphen Manon is a researcher affiliated with the University of Bordeaux in France, focusing primarily on biochemistry, genetics, and molecular biology. Their body of work encompasses a range of topics related to cellular processes, particularly those involving cell death mechanisms and mitochondrial function.

Their research has been published in multiple scientific venues, with repeated contributions to the journal Biomolecules, as well as publications in Science Advances, Cell Death and Disease, and the International Journal of Biological Macromolecules. Manon's scholarly articles often explore the intricate pathways and molecular players that regulate apoptosis and mitochondrial activity.

Key recent papers include:

  • "Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis," 2020, Science Advances
  • "Bcl-2 Family Members and the Mitochondrial Import Machineries: The Roads to Death," 2022, Biomolecules
  • "TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis," 2021, Cell Death and Disease
  • "Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae," 2021, International Journal of Biological Macromolecules
  • "Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax," 2022, APOPTOSIS

Frequent coauthors in Manon's collaborative research include Akandé Rouchidane Eyitayo, Laetitia Daury, Susana R. Chaves, Manuela Côrte-Real, and Cécile Gonzalez, indicating a network of scientific partnerships within the field.

The main fields of study covered by Manon's publications are:

  • Biochemistry, Genetics and Molecular Biology

Within this, the research focuses on specific subfields including:

  • Molecular Biology
  • Epidemiology
  • Immunology
  • Cell Biology
  • Nutrition and Dietetics

The main research topics addressed include:

  • Cell death mechanisms and regulation
  • Mitochondrial Function and Pathology
  • RNA Interference and Gene Delivery
  • Lipid Membrane Structure and Behavior
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Fungal and yeast genetics research

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Uth1p is involved in the autophagic degradation of mitochondria

    Ingrid Kissová;Maïka Deffieu;Stéphen Manon;Nadine Camougrand

  • Bax activation and mitochondrial insertion during apoptosis.

    Lisenn Lalier;Pierre-François Cartron;Pierre-François Cartron;Philippe Juin;Philippe Juin;Svetlana Nedelkina

  • Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xL

    Stéphen Manon;Bhabatosh Chaudhuri;Martine Guérin

  • A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast.

    Evgeny V. Pavlov;Muriel Priault;Dawn Pietkiewicz;Emily H.-Y. Cheng

  • Mitochondria as the target of the pro-apoptotic protein Bax.

    Emine Er;Lisa Oliver;Pierre-François Cartron;Philippe Juin

  • Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins.

    Laurent M. Dejean;Sonia Martinez-Caballero;Stephen Manon;Kathleen W. Kinnally

  • Selective and non-selective autophagic degradation of mitochondria in yeast.

    Ingrid Bhatia Kiššová;Bénédicte Salin;Jacques Schaeffer;Sapan Bhatia

  • tBid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak

    F. Gonzalvez;F. Pariselli;P. Dupaigne;I. Budihardjo

  • Guidelines and recommendations on yeast cell death nomenclature

    Didac Carmona-Gutierrez;Maria Anna Bauer;Andreas Zimmermann;Andrés Aguilera

  • TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax

    Bellot G;Bellot G;Cartron Pf;Cartron Pf;Er E;Er E;Oliver L;Oliver L

  • Investigation of bax-induced release of cytochrome c from yeast mitochondria permeability of mitochondrial membranes, role of VDAC and ATP requirement.

    Muriel Priault;Bhabatosh Chaudhuri;Angela Clow;Nadine Camougrand

  • Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

    Tristan Gallenne;Fabien Gautier;Fabien Gautier;Lisa Oliver;Lisa Oliver;Eric Hervouet;Eric Hervouet

  • ADP/ATP carrier is required for mitochondrial outer membrane permeabilization and cytochrome c release in yeast apoptosis.

    Clara Pereira;Nadine Camougrand;Stéphen Manon;Maria João Sousa

  • Organization and regulation of the cytosolic NADH metabolism in the yeast Saccharomyces cerevisiae.

    Michel Rigoulet;Hugo Aguilaniu;Hugo Aguilaniu;Nicole Avéret;Odile Bunoust

  • Bax: Addressed to kill.

    Thibaud T. Renault;Stéphen Manon

  • Glutathione Participates in the Regulation of Mitophagy in Yeast

    Maika Deffieu;Ingrid Bhatia-Kiššová;Ingrid Bhatia-Kiššová;Bénédicte Salin;Anne Galinier

  • The N-terminal end of Bax contains a mitochondrial-targeting signal.

    Pierre-François Cartron;Muriel Priault;Lisa Oliver;Khaled Meflah

  • Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-xL: Keep your friends close but your enemies closer

    Thibaud T. Renault;Oscar Teijido;Bruno Antonsson;Laurent M. Dejean

  • Distinct domains control the addressing and the insertion of Bax into mitochondria.

    Pierre-François Cartron;Hubert Arokium;Hubert Arokium;Lisa Oliver;Khaled Meflah

Frequent Co-Authors

Lisa Oliver
Lisa Oliver University of Nantes
Bruno Antonsson
Bruno Antonsson Merck Serono (Italy)
Michel Rigoulet
Michel Rigoulet Centre national de la recherche scientifique, CNRS
Hernâni Gerós
Hernâni Gerós University of Minho
Bernd Schierwater
Bernd Schierwater University of Veterinary Medicine Hannover, Foundation
Kathleen W. Kinnally
Kathleen W. Kinnally New York University
Pascale Cossart
Pascale Cossart Institut Pasteur
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Enza Maria Valente
Enza Maria Valente University of Pavia

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