Her primary areas of investigation include Cell biology, Mitochondrion, Cytochrome c, Membrane and Bcl-2-associated X protein. Her studies deal with areas such as Vesicle, Lipid bilayer, Apoptosis and Bcl-2 family as well as Cell biology. She has researched Lipid bilayer in several fields, including Membrane fluidity and Plasma protein binding.
Her Bcl-2 family study integrates concerns from other disciplines, such as Function and Inner mitochondrial membrane. Her study focuses on the intersection of Mitochondrion and fields such as Programmed cell death with connections in the field of Autophagy. The various areas that Ana J. García-Sáez examines in her Membrane study include Protein structure, Protein folding, Protein degradation and Protein–protein interaction.
Cell biology, Membrane, Biophysics, Apoptosis and Mitochondrion are her primary areas of study. Her Cell biology study frequently draws connections to adjacent fields such as Programmed cell death. Ana J. García-Sáez has included themes like Plasma protein binding and Fluorescence correlation spectroscopy in her Membrane study.
Her work carried out in the field of Biophysics brings together such families of science as Membrane structure, Bilayer, Biochemistry and Bioinformatics. In general Apoptosis, her work in Mitochondrial outer membrane permeabilization and Caspase is often linked to Interaction network, Interactome and Context linking many areas of study. Her Mitochondrion study incorporates themes from Membrane curvature, Cardiolipin, Bcl-2 family and Organelle.
Cell biology, Apoptosis, Membrane, Mitochondrion and Programmed cell death are her primary areas of study. Her study in the field of Mitochondrial outer membrane permeabilization and Caspase is also linked to topics like Protein network and Dynamic network analysis. Her Membrane research includes themes of Cell, Biophysics and Transmembrane protein.
Her Mitochondrion research incorporates elements of Cytoplasm, Bcl-2 family, Organelle and Function. The concepts of her Programmed cell death study are interwoven with issues in Necrosis, Intracellular and Effector. Her research integrates issues of Immunogenic cell death and Neuroscience in her study of Intrinsic apoptosis.
The scientist’s investigation covers issues in Cell biology, Apoptosis, Programmed cell death, Mitochondrion and Membrane. Her is doing research in Inner mitochondrial membrane and Ionomycin, both of which are found in Cell biology. Her work on Intrinsic apoptosis as part of general Apoptosis research is often related to Protein family, thus linking different fields of science.
Her Programmed cell death research is multidisciplinary, relying on both Cancer cell, Phosphatidylserine and Peptide. As a part of the same scientific family, Ana J. García-Sáez mostly works in the field of Mitochondrion, focusing on Function and, on occasion, Mitochondrial outer membrane permeabilization, Bcl-2 family, Organelle and Effector. Her Membrane research includes elements of Protein structure, Cell, Biophysics and Necrosis.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams.
Nature (2018)
Effect of line tension on the lateral organization of lipid membranes
Ana J. García-Sáez;Salvatore Chiantia;Petra Schwille.
Journal of Biological Chemistry (2007)
Bax, Bak and beyond - mitochondrial performance in apoptosis.
Aida Peña-Blanco;Ana J. García-Sáez;Ana J. García-Sáez.
FEBS Journal (2018)
The secrets of the Bcl-2 family
A J García-Sáez.
Cell Death & Differentiation (2012)
Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores.
Raquel Salvador‐Gallego;Raquel Salvador‐Gallego;Markus Mund;Katia Cosentino;Katia Cosentino;Jale Schneider.
The EMBO Journal (2016)
Structural Model of Active Bax at the Membrane
Stephanie Bleicken;Gunnar Jeschke;Carolin Stegmueller;Carolin Stegmueller;Carolin Stegmueller;Raquel Salvador-Gallego;Raquel Salvador-Gallego;Raquel Salvador-Gallego.
Molecular Cell (2014)
Membrane-insertion fragments of Bcl-xL, Bax, and Bid.
Ana J. García-Sáez;Ismael Mingarro;Enrique Pérez-Payá;Jesús Salgado.
Biochemistry (2004)
Mitochondrial alterations in apoptosis.
Katia Cosentino;Ana Jesus García-Sáez;Ana Jesus García-Sáez;Ana Jesus García-Sáez.
Chemistry and Physics of Lipids (2014)
Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.
Ana J. García-Sáez;Salvatore Chiantia;Jesús Salgado;Petra Schwille.
Biophysical Journal (2007)
Membrane promotes tBID interaction with BCL XL
Ana J García-Sáez;Jonas Ries;Mar Orzáez;Enrique Pérez-Payà.
Nature Structural & Molecular Biology (2009)
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