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Ruth M. Kluck

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
18666
World Ranking
19020
National Ranking
561

Ruth M. Kluck publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Ruth M. Kluck sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 80 publications — 1st percentile

1% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Ruth M. Kluck D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Ruth M. Kluck sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 45 D-Index — 3rd percentile

3% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Ruth M. Kluck is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with notable work in Molecular Biology, Oncology, Organic Chemistry, Genetics, and Radiology, Nuclear Medicine and Imaging.

The scientist's major research topics include:

  • Cell death mechanisms and regulation
  • RNA Interference and Gene Delivery
  • Chronic Lymphocytic Leukemia Research
  • Ubiquitin and proteasome pathways
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology

Ruth M. Kluck has contributed to several peer-reviewed papers in well-known scientific journals. Recent publications include:

  • Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias, 2021, Blood
  • BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells, 2022, Cell Death and Differentiation
  • Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target, 2020, Cell Death and Disease
  • Structure of detergent-activated BAK dimers derived from the inert monomer, 2021, Molecular Cell
  • The BCL-2 family member BID plays a role during embryonic development in addition to its BH3-only protein function by acting in parallel to BAX, BAK and BOK, 2022, The EMBO Journal

The frequent publication venues for the scientist include:

  • Cell Death and Differentiation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Crystallographica Section A Foundations and Advances
  • Blood
  • The EMBO Journal

Collaborations have been established with several co-authors who appear frequently in their work. These include:

  • Rachel T. Uren
  • Sweta Iyer
  • Peter E. Czabotar
  • Melissa X. Shi
  • Andreas Strasser

Best Publications

  • The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

    Ruth M. Kluck;Ella Bossy-Wetzel;Douglas R. Green;Donald D. Newmeyer

  • Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

    Elizabeth A. Slee;Mary T. Harte;Ruth M. Kluck;Beni B. Wolf

  • Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

    Simon N. Willis;Jamie I. Fletcher;Thomas Kaufmann;Mark F. van Delft;Mark F. van Delft

  • Molecular biology of Bax and Bak activation and action

    Dana Westphal;Grant Dewson;Peter E. Czabotar;Ruth M. Kluck

  • Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.

    Peter E. Czabotar;Peter E. Czabotar;Dana Westphal;Dana Westphal;Grant Dewson;Grant Dewson;Stephen Ma;Stephen Ma

  • Cytochrome c activation of CPP32‐like proteolysis plays a critical role in a Xenopus cell‐free apoptosis system

    Ruth M. Kluck;Seamus J. Martin;Brian M. Hoffman;Jian S. Zhou

  • Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis.

    D Westphal;R M Kluck;G Dewson

  • Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

    Grant Dewson;Ruth M. Kluck

  • The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol

    Ruth M Kluck;Mauro Dogli Esposti;Guy Perkins;Christian Renken

  • To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

    Grant Dewson;Tobias Kratina;Huiyan W. Sim;Hamsa Puthalakath

  • Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release.

    Oliver von Ahsen;Christian Renken;Guy Perkins;Ruth M. Kluck

  • Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices

    Grant Dewson;Tobias Kratina;Peter Czabotar;Catherine L. Day

  • Mitochondrial Release of Pro-apoptotic Proteins ELECTROSTATIC INTERACTIONS CAN HOLD CYTOCHROME c BUT NOT Smac/DIABLO TO MITOCHONDRIAL MEMBRANES

    Rachel T Uren;Grant Dewson;Christine Bonzon;Trevor James Lithgow

  • A Distinct Pathway of Cell-Mediated Apoptosis Initiated by Granulysin

    Allan A. Kaspar;Satoshi Okada;Jayant Kumar;Francis R. Poulain

  • Bax dimerizes via a symmetric BH3:groove interface during apoptosis

    G Dewson;S Ma;P Frederick;P Frederick;C Hockings

  • Determinants of Cytochrome c Pro-apoptotic Activity: THE ROLE OF LYSINE 72 TRIMETHYLATION *

    Ruth M. Kluck;Lisa M. Ellerby;H.Michael Ellerby;Shahrouz Naiem

  • Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak

    Rachel T. Uren;Grant Dewson;Lin Chen;Stephanie C. Coyne

  • Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers

    Jason M. Brouwer;Jason M. Brouwer;Dana Westphal;Dana Westphal;Grant Dewson;Grant Dewson;Adeline Y. Robin;Adeline Y. Robin

  • VDAC2 enables BAX to mediate apoptosis and limit tumor development.

    Hui San Chin;Hui San Chin;Mark X. Li;Mark X. Li;Iris K. L. Tan;Robert L. Ninnis;Robert L. Ninnis

  • Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane

    Dana Westphal;Grant Dewson;Marie Menard;Paul Frederick

Frequent Co-Authors

Grant Dewson
Grant Dewson Walter and Eliza Hall Institute of Medical Research
Peter E. Czabotar
Peter E. Czabotar Walter and Eliza Hall Institute of Medical Research
Donald D. Newmeyer
Donald D. Newmeyer La Jolla Institute For Allergy & Immunology
Jerry M. Adams
Jerry M. Adams Walter and Eliza Hall Institute of Medical Research
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Peter M. Colman
Peter M. Colman Walter and Eliza Hall Institute of Medical Research
Erinna F. Lee
Erinna F. Lee La Trobe University
Michael T. Ryan
Michael T. Ryan University of Sydney
Brian J. Smith
Brian J. Smith QIMR Berghofer Medical Research Institute
Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital

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Best Scientists Citing Ruth M. Kluck

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Publications: 42

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