World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
75
Citations
24285
World Ranking
1989
National Ranking
952

Overview

James W. Murrough is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily focuses on neuroscience and medicine, with an emphasis on pharmacology, biological psychiatry, cognitive neuroscience, clinical psychology, and experimental and cognitive psychology.

Their work covers several main topics, including:

  • Treatment of Major Depression
  • Tryptophan and brain disorders
  • Functional Brain Connectivity Studies
  • Stress Responses and Cortisol
  • Mental Health Research Topics
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Electroconvulsive Therapy Studies

Murrough has contributed frequently to several scientific publication venues. These include:

  • Biological Psychiatry
  • The Journal of Clinical Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Psychiatry
  • Neuropsychopharmacology

Their co-authors with whom they have collaborated extensively include:

  • Laurel Morris
  • Sara Costi
  • Dennis S. Charney
  • Adriana Feder
  • Sanjay J. Mathew

Recent publications by Murrough include the following works:

  • "Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation," 2021, American Journal of Psychiatry
  • "Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions," 2023, World Psychiatry
  • "Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options," 2020, Frontiers in Psychiatry
  • "Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression," 2023, New England Journal of Medicine
  • "A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia," 2020, Nature Medicine

Best Publications

  • Neurobiology of Resilience

    Scott J. Russo;James W. Murrough;Ming–Hu Han;Dennis S. Charney

  • Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

    James W. Murrough;Dan V. Iosifescu;Lee C. Chang;Rayan K. Al Jurdi

  • Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

    James W. Murrough;Andrew M. Perez;Sarah Pillemer;Jessica Stern

  • Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress.

    Georgia E. Hodes;Madeline L. Pfau;Marylene Leboeuf;Sam A. Golden

  • Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study

    Ahmed Tawakol;Amorina Ishai;Richard Ap Takx;Amparo L Figueroa

  • The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

    Samuel T. Wilkinson;Elizabeth D. Ballard;Michael H. Bloch;Sanjay J. Mathew

  • Lack of ventral striatal response to positive stimuli in depressed versus normal subjects

    Jane Epstein;Hong Pan;James H Kocsis;Yihong Yang

  • Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation

    Roger S McIntyre;Roger S McIntyre;Joshua D Rosenblat;Joshua D Rosenblat;Charles B Nemeroff;Gerard Sanacora

  • Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder: A Randomized Clinical Trial

    Adriana Feder;Michael K. Parides;James W. Murrough;Andrew M. Perez

  • Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression

    Marije aan het Rot;Katherine A. Collins;James W. Murrough;Andrew M. Perez

  • Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions

    Unknown

  • A Randomized Controlled Trial of Intranasal Ketamine in Major Depressive Disorder

    Kyle A.B. Lapidus;Cara F. Levitch;Andrew M. Perez;Jess W. Brallier

  • A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression

    Jaskaran B. Singh;Maggie Fedgchin;Ella J. Daly;Peter De Boer

  • Targeting glutamate signalling in depression: progress and prospects

    James W. Murrough;Chadi G. Abdallah;Sanjay J. Mathew

  • Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

    Maurizio Fava;Marlene P. Freeman;Martina Flynn;Heidi Judge

  • Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options.

    Amir Garakani;Amir Garakani;James W. Murrough;Rafael C. Freire;Robyn P. Thom

  • Cognitive dysfunction in depression: neurocircuitry and new therapeutic strategies.

    James W. Murrough;Brian Iacoviello;Brian Iacoviello;Alexander Neumeister;Dennis S. Charney

  • EFFECTS OF KETAMINE ON EXPLICIT AND IMPLICIT SUICIDAL COGNITION: A RANDOMIZED CONTROLLED TRIAL IN TREATMENT‐RESISTANT DEPRESSION

    Rebecca B. Price;Dan V. Iosifescu;James W. Murrough;Lee C. Chang

  • Screening and Management of Depression in Patients With Cardiovascular Disease: JACC State-of-the-Art Review.

    Manish K. Jha;Arman Qamar;Muthiah Vaduganathan;Dennis S. Charney

  • ECT in Treatment-Resistant Depression

    Charles H. Kellner;Robert M. Greenberg;James W. Murrough;Ethan O. Bryson

  • Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial.

    J. W. Murrough;L. Soleimani;K. E. DeWilde;K. A. Collins

  • Ketamine for treatment-resistant unipolar depression: current evidence.

    Sanjay J. Mathew;Sanjay J. Mathew;Sanjay J. Mathew;Asim Shah;Kyle Lapidus;Crystal Clark;Crystal Clark

  • Amino Acid Neurotransmitters Assessed by Proton Magnetic Resonance Spectroscopy : Relationship to Treatment Resistance in Major Depressive Disorder

    Rebecca B. Price;Dikoma C. Shungu;Xiangling Mao;Paul Nestadt

Frequent Co-Authors

Sanjay J. Mathew
Sanjay J. Mathew Baylor College of Medicine
Nicholas T. Van Dam
Nicholas T. Van Dam University of Melbourne
Scott J. Russo
Scott J. Russo Icahn School of Medicine at Mount Sinai
Wayne K. Goodman
Wayne K. Goodman Baylor College of Medicine
Prantik Kundu
Prantik Kundu Icahn School of Medicine at Mount Sinai
Ming-Hu Han
Ming-Hu Han Icahn School of Medicine at Mount Sinai
Diego A. Pizzagalli
Diego A. Pizzagalli Harvard University
Katherine E. Burdick
Katherine E. Burdick Brigham and Women's Hospital
Sarah H. Lisanby
Sarah H. Lisanby Arizona State University
Natalie L. Rasgon
Natalie L. Rasgon Stanford University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing James W. Murrough

Trending Scientists