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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
46279
World Ranking
3062
National Ranking
70

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Santos A. Susin is affiliated with Grenoble Alpes University in France, conducting research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their publications span core subfields such as Genetics, Molecular Biology, Immunology, Pathology and Forensic Medicine, and Hematology.

Their work predominantly focuses on topics related to Chronic Lymphocytic Leukemia Research, which accounts for a significant portion of their output. Other research interests include Lymphoma Diagnosis and Treatment, Phagocytosis and Immune Regulation, Immunodeficiency and Autoimmune Disorders, Acute Lymphoblastic Leukemia research, Glycosylation and Glycoproteins Research, and Acute Myeloid Leukemia Research.

Frequent coauthors in their publications include Florence Nguyen-Khac, Élise Chapiro, Brigitte Bauvois, Damien Roos-Weil, and Delphine Garnier. The most common venues for their research publications are the journals Cancers, Leukemia, Biomedicines, British Journal of Haematology, and Blood.

Recent papers authored or coauthored by Santos A. Susin include:

  • "Cytogenetic and molecular abnormalities in Waldenström's macroglobulinemia patients: Correlations and prognostic impact," 2021, American Journal of Hematology
  • "Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus," 2020, Molecular Metabolism
  • "ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia," 2023, Leukemia
  • "Relation of Neutrophil Gelatinase-Associated Lipocalin Overexpression to the Resistance to Apoptosis of Tumor B Cells in Chronic Lymphocytic Leukemia," 2020, Cancers
  • "Activation of Interferon Signaling in Chronic Lymphocytic Leukemia Cells Contributes to Apoptosis Resistance via a JAK-Src/STAT3/Mcl-1 Signaling Pathway," 2021, Biomedicines

Best Publications

  • Molecular characterization of mitochondrial apoptosis-inducing factor

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • Mitochondrial control of apoptosis

    Guido Kroemer;Naoufal Zamzami;Santos A. Susin

  • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

    Nicholas Joza;Nicholas Joza;Santos A. Susin;Eric Daugas;William L. Stanford

  • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

    Naoufal Zamzami;Philippe Marchetti;Maria Castedo;Didier Decaudin

  • Mitochondrial control of nuclear apoptosis

    Naoufal Zamzami;S. A. Susin;P. Marchetti;T. Hirsch

  • Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis

    Isabel Marzo;Catherine Brenner;Naoufal Zamzami;Juliane M. Jürgensmeier

  • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.

    S A Susin;N Zamzami;M Castedo;T Hirsch

  • Hsp27 negatively regulates cell death by interacting with cytochrome c

    Jean-Marie Bruey;Cécile Ducasse;Philippe Bonniaud;Luigi Ravagnan

  • Heat-shock protein 70 antagonizes apoptosis-inducing factor.

    Luigi Ravagnan;Sandeep Gurbuxani;Santos A. Susin;Carine Maisse

  • Mitochondrial permeability transition is a central coordinating event of apoptosis

    Philippe Marchetti;Maria Castedo;Santos A. Susin;Naoufal Zamzami

  • Mitochondria as regulators of apoptosis: doubt no more

    Santos A. Susin;Naoufal Zamzami;Guido Kroemer

  • Two distinct pathways leading to nuclear apoptosis.

    Santos A. Susin;Eric Daugas;Luigi Ravagnan;Kumiko Samejima

  • Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

    Eric Daugas;Santos A. Susin;Naoufal Zamzami;Karine F. Ferri

  • Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins.

    Isabel Marzo;Catherine Brenner;Naoufal Zamzami;Santos A. Susin

  • The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

    Santos A. Susin;Naoufal Zamzami;Maria Castedo;Eric Daugas

  • Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

    Hans Kristian Lorenzo;Santos A Susin;Josef Penninger;Guido Kroemer

  • The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death

    Tamara T. Hirsch;Piero Marchetti;Santos S. Susin;Bruno B. Dallaporta

  • Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis.

    Eric Daugas;Dominique Nochy;Luigi Ravagnan;Markus Loeffler

  • Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins.

    Naoufal Zamzami;Catherine Brenner;Isabel Marzo;Santos A Susin

Frequent Co-Authors

Guido Kroemer
Guido Kroemer Université Paris Cité
Naoufal Zamzami
Naoufal Zamzami Centre national de la recherche scientifique, CNRS
Isabel Marzo
Isabel Marzo University of Zaragoza
Josef M. Penninger
Josef M. Penninger University of British Columbia
Maria Castedo
Maria Castedo Université Paris Cité
Frederic Davi
Frederic Davi Assistance Publique – Hôpitaux de Paris
Catherine Brenner
Catherine Brenner Université Paris Cité
Marika Sarfati
Marika Sarfati University of Montreal
John C. Reed
John C. Reed Johnson & Johnson (United States)

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