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Philippe Marchetti

Philippe Marchetti

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
20228
World Ranking
11128
National Ranking
403

Overview

Philippe Marchetti is affiliated with Inserm in France and has a diverse research portfolio primarily within medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields including molecular biology, biomedical engineering, hematology, cancer research, and genetics.

The scientist's research topics cover several areas of biomedical science, with notable focus on mitochondrial function and pathology, cancer, hypoxia, and metabolism. Additional topics include acute myeloid leukemia research, adipose tissue and metabolism, 3D printing in biomedical research, corneal surgery and treatments, and the use of electrospun nanofibers in biomedical applications.

Recent publications by Philippe Marchetti include:

  • Mitochondrial spare respiratory capacity: Mechanisms, regulation, and significance in non-transformed and cancer cells, 2020, The FASEB Journal
  • Lipid Metabolism and Resistance to Anticancer Treatment, 2020, Biology
  • TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence, 2022, Nature Communications
  • Current Advances in 3D Bioprinting for Cancer Modeling and Personalized Medicine, 2022, International Journal of Molecular Sciences
  • Mitochondrial alterations triggered by repeated exposure to fine (PM2.5-0.18) and quasi-ultrafine (PM0.18) fractions of ambient particulate matter, 2020, Environment International

Philippe Marchetti frequently publishes in journals such as the International Journal of Molecular Sciences, Frontiers in Bioengineering and Biotechnology, bioRxiv (Cold Spring Harbor Laboratory), Blood, and The FASEB Journal.

Collaboration is evident in the scientist's work, with frequent coauthors including Nicolas Germain, Jérôme Kluza, William Laine, Quentin Fovez, and Salim Dekiouk. These collaborations indicate a network spanning various aspects of biomedical research and molecular biology.

Best Publications

  • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

    Naoufal Zamzami;Philippe Marchetti;Maria Castedo;Didier Decaudin

  • Mitochondrial control of nuclear apoptosis

    Naoufal Zamzami;S. A. Susin;P. Marchetti;T. Hirsch

  • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.

    S A Susin;N Zamzami;M Castedo;T Hirsch

  • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

    Naoufal Zamzami;P. Marchetti;M. Castedo;C. Zanin

  • Mitochondrial permeability transition is a central coordinating event of apoptosis

    Philippe Marchetti;Maria Castedo;Santos A. Susin;Naoufal Zamzami

  • The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death

    Tamara T. Hirsch;Piero Marchetti;Santos S. Susin;Bruno B. Dallaporta

  • Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis

    Naoufal Zamzami;Philippe Marchetti;Maria Castedo;Tamara Hirsch

  • Study of mitochondrial membrane potential, reactive oxygen species, DNA fragmentation and cell viability by flow cytometry in human sperm

    Carole Marchetti;Guillaume Obert;André Deffosez;Pierre Formstecher

  • Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.

    M Castedo;T Hirsch;S A Susin;N Zamzami

  • Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents

    Didier Decaudin;Stephan Geley;Tamara Hirsch;Maria Castedo

  • Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.

    A Macho;T Hirsch;I Marzo;P Marchetti

  • Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L-cells

    Mohamed-Sami Trabelsi;Mehdi Daoudi;Janne Prawitt;Sarah Ducastel

  • Mitochondrial permeability transition triggers lymphocyte apoptosis.

    P Marchetti;T Hirsch;N Zamzami;M Castedo

  • PK11195, A LIGAND OF THE MITOCHONDRIAL BENZODIAZEPINE RECEPTOR, FACILITATES THE INDUCTION OF APOPTOSIS AND REVERSES BCL-2-MEDIATED CYTOPROTECTION

    Tamara Hirsch;Didier Decaudin;Santos A. Susin;Philippe Marchetti

  • Redox regulation of apoptosis: Impact of thiol oxidation status on mitochondrial function

    Philippe Marchetti;Didier Decaudin;Antonio Macho;Naoufal Zamzami

  • Apoptosis-associated Derangement of Mitochondrial Function in Cells Lacking Mitochondrial DNA

    Philippe Marchetti;Santos A. Susin;Didier Decaudin;Susana Gamen

  • The functionality of mitochondria differentiates human spermatozoa with high and low fertilizing capability

    Frédérique Gallon;Carole Marchetti;Nathalie Jouy;Philippe Marchetti

  • Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437

    Anne-Sophie Belzacq;Chahrazed El Hamel;Helena L A Vieira;Isabel Cohen

  • Comparison of four fluorochromes for the detection of the inner mitochondrial membrane potential in human spermatozoa and their correlation with sperm motility

    Carole Marchetti;Nathalie Jouy;Brigitte Leroy-Martin;André Defossez

  • Caspase inhibition prevents cardiac dysfunction and heart apoptosis in a rat model of sepsis.

    Rémi Nevière;Harold Fauvel;Claude Chopin;Pierre Formstecher

Frequent Co-Authors

Guido Kroemer
Guido Kroemer Université Paris Cité
Naoufal Zamzami
Naoufal Zamzami Centre national de la recherche scientifique, CNRS
Santos A. Susin
Santos A. Susin Grenoble Alpes University
Maria Castedo
Maria Castedo Université Paris Cité
Bertrand Joseph
Bertrand Joseph Karolinska Institute
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Philippe Gosset
Philippe Gosset Institut Pasteur
Catherine Brenner
Catherine Brenner Université Paris Cité
Isabel Marzo
Isabel Marzo University of Zaragoza
David Devos
David Devos University of Lille

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