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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
17995
World Ranking
16446
National Ranking
367

Overview

Isabel Marzo is affiliated with the University of Zaragoza in Spain. Their research spans multiple fields, predominantly focusing on materials science and chemistry. The scientist's publications demonstrate significant involvement in both foundational and applied scientific studies across a variety of subfields and topics.

The main fields of study in which Isabel Marzo has contributed include:

  • Materials Science
  • Chemistry

Within these domains, their more specific subfields of study feature:

  • Materials Chemistry
  • Organic Chemistry
  • Immunology
  • Molecular Biology
  • Oncology

The key topics addressed in Isabel Marzo's work cover diverse aspects of chemistry and biomedical research, including:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Immune Cell Function and Interaction
  • Metal complexes synthesis and properties
  • Click Chemistry and Applications
  • Crystallography and molecular interactions
  • Multiple Myeloma Research and Treatments

Notable frequent coauthors accompanying Isabel Marzo in research outputs are:

  • M. Concepción Gimeno (36 collaborations)
  • Alberto Anel (19 collaborations)
  • Vanesa Fernández-Moreira (18 collaborations)
  • Javier Naval (11 collaborations)
  • Manuel Beltrán-Visiedo (11 collaborations)

Throughout their career, Isabel Marzo has published in several scientific venues, with the most frequent being:

  • The Cambridge Structural Database (17 publications)
  • Chemistry - A European Journal (5 publications)
  • OncoImmunology (3 publications)
  • Cells (3 publications)
  • Preprints.org (3 publications)

Among recent papers authored or coauthored by Isabel Marzo are:

  • "Future prospects for mitosis-targeted antitumor therapies," 2021, Biochemical Pharmacology
  • "Expanded NK cells from umbilical cord blood and adult peripheral blood combined with daratumumab are effective against tumor cells from multiple myeloma patients," 2020, OncoImmunology
  • "Synthesis of New Thiourea-Metal Complexes with Promising Anticancer Properties," 2021, Molecules
  • "Luminescent Re(I)/Au(I) Species As Selective Anticancer Agents for HeLa Cells," 2020, Inorganic Chemistry
  • "Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance," 2020, Scientific Reports

Isabel Marzo's research contributions reflect an intersection of chemical synthesis, crystallographic analysis, and biomedical applications, particularly with a focus on anticancer therapies and immune cell functionality within oncology. The works involving metal complexes and their properties further emphasize the chemical and materials science foundation supporting the biomedical investigations carried out.

Best Publications

  • Molecular characterization of mitochondrial apoptosis-inducing factor

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis

    Isabel Marzo;Catherine Brenner;Naoufal Zamzami;Juliane M. Jürgensmeier

  • Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins.

    Isabel Marzo;Catherine Brenner;Naoufal Zamzami;Santos A. Susin

  • The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death

    Tamara T. Hirsch;Piero Marchetti;Santos S. Susin;Bruno B. Dallaporta

  • Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins.

    Naoufal Zamzami;Catherine Brenner;Isabel Marzo;Santos A Susin

  • Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator.

    Catherine Brenner;Hervé Cadiou;Helena La Vieira;Naoufal Zamzami

  • Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.

    A Macho;T Hirsch;I Marzo;P Marchetti

  • Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

    Nathanael Larochette;Didier Decaudin;Didier Decaudin;Etienne Jacotot;Catherine Brenner

  • Nitric oxide induces apoptosis via triggering mitochondrial permeability transition

    Sonsoles Hortelano;Sonsoles Hortelano;Bruno Dallaporta;Naoufal Zamzami;Tamara Hirsch

  • Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes

    Didier Métivier;Bruno Dallaporta;Naoufal Zamzami;Nathanael Larochette

  • Role of the Mitochondrial Permeability Transition Pore in Apoptosis

    Tamara Hirsch;Isabel Marzo;Guido Kroemer

  • Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore.

    Luigi Ravagnan;Isabel Marzo;Paola Costantini;Santos A Susin

  • Mitochondria in chemotherapy-induced apoptosis: a prospective novel target of cancer therapy (review).

    D Decaudin;I Marzo;C Brenner;G Kroemer

  • Potassium Leakage During the Apoptotic Degradation Phase

    Bruno Dallaporta;Tamara Hirsch;Santos A. Susin;Naoufal Zamzami

  • The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition.

    Naoufal Zamzami;Isabel Marzo;Santos A Susin;Catherine Brenner

  • Immunogenic Cell Death and Immunotherapy of Multiple Myeloma.

    Alfonso Serrano-del Valle;Alberto Anel;Javier Naval;Isabel Marzo

  • Caspases disrupt mitochondrial membrane barrier function

    Isabel Marzo;Santos A Susin;Patrice X Petit;Luigi Ravagnan

  • Mitochondrial permeability transition in apoptosis and necrosis.

    T. Hirsch;S. A. Susin;I. Marzo;P. Marchetti

  • A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

    Julián Pardo;Patricia Pérez-Galán;Susana Gamen;Isabel Marzo

Frequent Co-Authors

Javier Naval
Javier Naval University of Zaragoza
Alberto Anel
Alberto Anel University of Zaragoza
Guido Kroemer
Guido Kroemer Université Paris Cité
M. Concepción Gimeno
M. Concepción Gimeno University of Zaragoza
Santos A. Susin
Santos A. Susin Grenoble Alpes University
Naoufal Zamzami
Naoufal Zamzami Centre national de la recherche scientifique, CNRS
Catherine Brenner
Catherine Brenner Université Paris Cité
John C. Reed
John C. Reed Johnson & Johnson (United States)
Antonio Laguna
Antonio Laguna University of Zaragoza

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