World's Best Scientists 2026 revealed!
Award Badge
Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
33005
World Ranking
4452
National Ranking
108

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award
  • 2014 - Fellow of the Royal Society, United Kingdom

Overview

Peter M. Colman is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions to molecular biology, organic chemistry, oncology, cell biology, and materials chemistry.

The main topics addressed in their work include lipid membrane structure and behavior, cell death mechanisms and regulation, RNA interference and gene delivery, ion channel regulation and function, mitochondrial function and pathology, endoplasmic reticulum stress and disease, and RNA regulation and disease.

Key recent publications by Peter M. Colman include:

  • BAK core dimers bind lipids and can be bridged by them, 2020, Nature Structural & Molecular Biology
  • Structure of detergent-activated BAK dimers derived from the inert monomer, 2021, Molecular Cell
  • Ion currents through Kir potassium channels are gated by anionic lipids, 2022, Nature Communications
  • An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration, 2022, Scientific Reports
  • Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids, 2023, FEBS Journal

Frequent coauthors with whom they have collaborated include:

  • Peter E. Czabotar
  • Brian J. Smith
  • Ahmad Z. Wardak
  • Nicholas A. Smith
  • Jacqueline M. Gulbis

Their work has appeared in several scientific journals such as:

  • Nature Structural & Molecular Biology
  • Molecular Cell
  • Nature Communications
  • FEBS Journal
  • Scientific Reports

In 2014, Peter M. Colman was recognized as a Fellow of the Royal Society, United Kingdom.

Best Publications

  • Rational design of potent sialidase-based inhibitors of influenza virus replication.

    Mark von Itzstein;Wen-Yang Wu;Gaik B. Kok;Michael S. Pegg

  • Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

    Lin Chen;Simon N. Willis;Andrew Wei;Brian J. Smith

  • Conformations of immunoglobulin hypervariable regions.

    Cyrus Chothia;Cyrus Chothia;Arthur M. Lesk;Anna Tramontano;Michael Levitt;Michael Levitt

  • Shape Complementarity at Protein/Protein Interfaces

    Michael C. Lawrence;Peter M. Colman

  • Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution

    J. N. Varghese;W. G. Laver;P. M. Colman

  • Structure of the catalytic and antigenic sites in influenza virus neuraminidase

    P. M. Colman;J. N. Varghese;W. G. Laver

  • Effects of amino acid sequence changes on antibody-antigen interactions.

    P.M. Colman

  • X-ray crystal structure analysis of plastocyanin at 2.7 Å resolution

    P. M. Colman;H. C. Freeman;J. M. Guss;M. Murata

  • BCL-2 family antagonists for cancer therapy

    Guillaume Lessene;Peter E. Czabotar;Peter M. Colman

  • Three-dimensional structure of a complex of antibody with influenza virus neuraminidase.

    P. M. Colman;W. G. Laver;J. N. Varghese;A. T. Baker

  • Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.

    Peter E. Czabotar;Peter E. Czabotar;Dana Westphal;Dana Westphal;Grant Dewson;Grant Dewson;Stephen Ma;Stephen Ma

  • The structural biology of type I viral membrane fusion.

    Peter M. Colman;Michael C. Lawrence

  • Crystallographic structure studies of an IgG molecule and an Fc fragment

    Robert Huber;Robert Huber;Johann Deisenhofer;Peter M. Colman;Peter M. Colman;Peter M. Colman;Masaaki Matsushima;Masaaki Matsushima

  • The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

    Joseph N. Varghese;Jennifer L. McKimm-Breschkin;James B. Caldwell;Alexander A. Kortt

  • Structural insights into the degradation of Mcl-1 induced by BH3 domains.

    Peter E. Czabotar;Erinna F. Lee;Mark F. van Delft;Catherine L. Day

  • Influenza virus neuraminidase: structure, antibodies, and inhibitors.

    P.M. Colman

  • Structure-guided design of a selective BCL-XL inhibitor

    Guillaume Lessene;Guillaume Lessene;Peter Edward Czabotar;Peter Edward Czabotar;Brad Sleebs;Brad Sleebs;Kerry Zobel

  • The structure of thermolysin: an electron density map at 2-3 A resolution.

    P.M. Colman;J.N. Jansonius;B.W. Matthews

  • Three-dimensional Structure of Thermolysin

    B. W. Matthews;J. N. Jansonius;P. M. Colman;B. P. Schoenborn

  • To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

    Grant Dewson;Tobias Kratina;Huiyan W. Sim;Hamsa Puthalakath

Frequent Co-Authors

Peter E. Czabotar
Peter E. Czabotar Walter and Eliza Hall Institute of Medical Research
Brian J. Smith
Brian J. Smith QIMR Berghofer Medical Research Institute
David C. S. Huang
David C. S. Huang Walter and Eliza Hall Institute of Medical Research
Erinna F. Lee
Erinna F. Lee La Trobe University
Guillaume Lessene
Guillaume Lessene Walter and Eliza Hall Institute of Medical Research
W. Douglas Fairlie
W. Douglas Fairlie La Trobe University
Jonathan B. Baell
Jonathan B. Baell Monash University
Grant Dewson
Grant Dewson Walter and Eliza Hall Institute of Medical Research
W.G. Laver
W.G. Laver Australian National University
Robert G. Webster
Robert G. Webster St. Jude Children's Research Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Biology or Biochemistry opens up diverse professional pathways, many of which can be further enhanced by specialized online programs. For those interested in leadership roles within healthcare, a fastest online mha (Master of Healthcare Administration) can offer a rapid and flexible route to a career in healthcare management.

If your interests lie at the intersection of biology and mental health, you might consider a fast track mental health nursing program, which is designed for those seeking advanced nursing roles focused on psychiatric care.

Nutrition is another dynamic field closely connected to biochemistry. Earning an online nutrition degree can lead to roles in public health, clinical nutrition, or wellness coaching. Finally, if you are aiming to combine business acumen with biological sciences, the mba healthcare management online is a cost-effective choice, equipping graduates with skills for management and business strategy roles in healthcare sectors.

Best Scientists Citing Peter M. Colman

Trending Scientists