World's Best Scientists 2026 revealed!
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Medicine
Brazil
2023

D-Index & Metrics

Medicine

D-Index
101
Citations
34655
World Ranking
8035
National Ranking
20

Research.com Recognitions

  • 2023 - Research.com Medicine in Brazil Leader Award
  • 2022 - Research.com Medicine in Brazil Leader Award

Overview

João B. Calixto is affiliated with the Universidade Federal de Santa Catarina in Brazil. Their research primarily falls within the field of Medicine, with a focus on several subfields including Molecular Biology, Physiology, Immunology, Sensory Systems, and Genetics.

The scientist's recent publications cover a range of topics central to pharmacology, neurobiology, and immunological responses. Some of the recent papers include:

  • Taxane-induced neurotoxicity: Pathophysiology and therapeutic perspectives, 2020, British Journal of Pharmacology
  • Bradykinin Receptors Play a Critical Role in the Chronic Post-ischaemia Pain Model, 2020, Cellular and Molecular Neurobiology
  • Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury, 2023, Cytokine & Growth Factor Reviews
  • miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4, 2022, Journal of Investigative Dermatology
  • Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation, 2023, Nature Communications

Publications by João B. Calixto have appeared frequently in several journals, including:

  • British Journal of Pharmacology
  • European Journal of Pharmacology
  • Pulmonary Pharmacology & Therapeutics
  • Cellular and Molecular Neurobiology
  • Cytokine & Growth Factor Reviews

João B. Calixto's research topics cover a variety of essential areas, such as:

  • Ion Channels and Receptors
  • Pain Mechanisms and Treatments
  • Ion channel regulation and function
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Dermatology and Skin Diseases
  • Mosquito-borne diseases and control
  • Mast cells and histamine

The scientist has collaborated frequently with several researchers, including:

  • Daniela Almeida Cabrini
  • Michel Fleith Otuki
  • Elizabeth S. Fernandes
  • Eunice Andrè
  • Adara A. Santos

Best Publications

  • Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents)

    J.B. Calixto

  • A review of the plants of the genus Phyllanthus: their chemistry, pharmacology, and therapeutic potential.

    João B. Calixto;Adair R. S. Santos;Valdir Cechinel Filho;Rosendo A. Yunes

  • Anti-inflammatory effects of compounds alpha-humulene and (−)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea

    Elizabeth S. Fernandes;Giselle F. Passos;Rodrigo Medeiros;Fernanda M. da Cunha

  • Twenty-five years of research on medicinal plants in Latin America: A personal view

    João B. Calixto

  • Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules.

    João B. Calixto;Maria M. Campos;Michel F. Otuki;Adair R. S. Santos

  • Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives.

    Rafael C. Dutra;Maria M. Campos;Adair R.S. Santos;João B. Calixto

  • Naturally occurring antinociceptive substances from plants.

    João B. Calixto;Alessandra Beirith;Juliano Ferreira;Adair R. S. Santos

  • Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors

    João B. Pesquero;Ronaldo C. Araujo;Paul A. Heppenstall;Cheryl L. Stucky

  • Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB).

    João B. Calixto;Michel F. Otuki;Adair R. S. Santos

  • Kinins in pain and inflammation

    João B. Calixto;Daniela A. Cabrini;Juliano Ferreira;Maria M. Campos

  • Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw.

    Alessandra Beirith;Adair R.S Santos;João B Calixto

  • The role of natural products in modern drug discovery

    João B Calixto

  • Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein.

    Rodrigo Medeiros;Rui D S Prediger;Giselle F Passos;Pablo Pandolfo

  • Depressive-like behavior induced by tumor necrosis factor-α in mice

    Manuella P. Kaster;Vinícius M. Gadotti;Vinícius M. Gadotti;João B. Calixto;Adair R.S. Santos

  • Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes

    João B Calixto;Rodrigo Medeiros;Elizabeth S Fernandes;Juliano Ferreira

  • Evidence for participation of B1 and B2 kinin receptors in formalin-induced nociceptive response in the mouse

    Clóvis R. Corrêa;João B. Calixto

  • Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea

    Giselle F. Passos;Elizabeth S. Fernandes;Fernanda M. da Cunha;Juliano Ferreira

  • Omega-3 Fatty Acid-Derived Mediators 17(R)-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

    Allisson Freire Bento;Rafaela Franco Claudino;Rafael Cypriano Dutra;Rodrigo Marcon

  • Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-d-aspartate receptors and the l-arginine-nitric oxide pathway

    Michela Mantovani;Roberto Pértile;João B. Calixto;Adair R.S. Santos

  • A Review of the Plants of the Genus Phyllanthus: Their Chemistry, Pharmacology, and Therapeutic Potential

    J. B. Calixto;A. R. S. Santos;V. Cechinel Filho;R. A. Yunes

Frequent Co-Authors

Rosendo A. Yunes
Rosendo A. Yunes Universidade Federal de Santa Catarina
Adair R.S. Santos
Adair R.S. Santos Universidade Federal de Santa Catarina
Juliano Ferreira
Juliano Ferreira Universidade Federal de Santa Maria
Ana Lúcia S. Rodrigues
Ana Lúcia S. Rodrigues Universidade Federal de Santa Catarina
Moacir Geraldo Pizzolatti
Moacir Geraldo Pizzolatti Universidade Federal de Santa Catarina
João Bosco Pesquero
João Bosco Pesquero Federal University of Sao Paulo
Michael Bader
Michael Bader Max Delbrück Center for Molecular Medicine
Reinaldo N. Takahashi
Reinaldo N. Takahashi Universidade Federal de Santa Catarina
Carlos Fernando Mello
Carlos Fernando Mello Universidade Federal de Santa Maria
Luiz Juliano
Luiz Juliano Federal University of Sao Paulo

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