World's Best Scientists 2026 revealed!
Christoph Borner

Christoph Borner

D-Index & Metrics

Molecular Biology

D-Index
61
Citations
34485
World Ranking
1872
National Ranking
131

Overview

Christoph Borner is a researcher affiliated with the University of Freiburg in Germany with a focus on Biochemistry, Genetics, and Molecular Biology, alongside Medicine. Their work spans several subfields, including Molecular Biology, Immunology, Pathology and Forensic Medicine, Epidemiology, and Parasitology.

Their research primarily centers on cell death mechanisms and regulation, a topic reflected in the majority of their publications. Other significant areas of investigation include autophagy in disease and therapy, studies on Toxoplasma gondii, phagocytosis and immune regulation, chemotherapy-induced organ toxicity mitigation, 3D printing in biomedical research, and cancer cells and metastasis.

Borner has published notable papers such as:

  • Apoptotic cell death in disease-Current understanding of the NCCD 2023 (2023, Cell Death and Differentiation)
  • Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells (2020, Communications Biology)
  • Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner (2020, Autophagy)
  • Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins (2020, Cell Death Discovery)
  • Caspase-8 is required for HSV-1-induced apoptosis and promotes effective viral particle release via autophagy inhibition (2022, Cell Death and Differentiation)

Their frequent coauthors include Lukas Peintner, Marcus Conrad, Ana J. García-Sáez, Philipp J. Jost, and Ilio Vitale. These collaborative relationships underline Borner's integration into research networks focused on cell death and autophagy.

Publication venues for Borner's work have included:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Cell Death and Differentiation
  • Communications Biology
  • Autophagy
  • Cell Death Discovery

Topics covered throughout Borner's career reveal a sustained interest in understanding cellular processes that regulate life and death at the molecular level. This includes the study of apoptotic pathways, lysosomal function, immune system interactions, and mechanisms of viral-induced cell death.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

    Thierry Rossé;Reynald Olivier;Laurent Monney;Monika Rager

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

    Patricio Godoy;Nicola J. Hewitt;Ute Albrecht;Melvin E. Andersen

  • The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions.

    Christoph Borner

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

    Reyhaneh Foyouzi-Youssefi;Serge Arnaudeau;Christoph Borner;William L. Kelley

  • XIAP discriminates between type I and type II FAS-induced apoptosis

    Philipp. Jost;Stephanie. Grabow;Stephanie. Grabow;Daniel. Gray;Mark D. McKenzie;Mark D. McKenzie

  • Characterization of the signal that directs Bcl-xL, but not Bcl-2, to the mitochondrial outer membrane

    Thomas Kaufmann;Sarah Schlipf;Javier Sanz;Karin Neubert

  • Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling.

    Tobias B. Huber;Björn Hartleben;Jeong Kim;Miriam Schmidts

  • Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2.

    Jürg Häcki;Lotti Egger;Laurent Monney;Laurent Monney;Sébastien Conus

  • Bcl-2 interrupts the ceramide-mediated pathway of cell death.

    Jiandi Zhang;Nejemie Alter;John C. Reed;Christoph Borner

  • Apoptosis without caspases: an inefficient molecular guillotine?

    Christoph Borner;Laurent Monney;Laurent Monney

  • Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.

    Christoph M Schempp;Vladimir Kirkin;Birgit Simon-Haarhaus;Astrid Kersten

  • Diminished Cell Proliferation Associated with the Death-protective Activity of Bcl-2

    Christoph Borner

  • Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2

    Denis Grandgirard;Erwin Studer;Laurent Monney;Tanja Belser

  • The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis.

    Christoph Borner;Isabelle Martinou;Chantal Mattmann;Martin Irmler

  • Volatile anesthetics induce caspase-dependent, mitochondria-mediated apoptosis in human T lymphocytes in vitro

    Torsten Loop;David Dovi-Akue;Michael Frick;Martin Roesslein

  • Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling

    Michaela Weber;Ali Gawanbacht;Matthias Habjan;Andreas Rang

Frequent Co-Authors

Irmgard Merfort
Irmgard Merfort University of Freiburg
Doriano Fabbro
Doriano Fabbro Novartis (Switzerland)
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Guido Kroemer
Guido Kroemer Université Paris Cité
Carmen Garrido
Carmen Garrido University of Burgundy
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Ilio Vitale
Ilio Vitale University of Rome Tor Vergata
Markus M. Simon
Markus M. Simon Max Planck Society
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology opens up numerous engaging fields and alternative academic options. If you’re drawn to creative applications, online graphic design courses offer a way to merge science communication with visual storytelling. These programs can help students effectively present complex scientific ideas to diverse audiences.

For those interested in customizing their studies and combining disciplines, affordable online interdisciplinary studies degrees enable you to blend biology with subjects like data analysis, ethics, or business—skills valued in biotech careers.

If you’re passionate about the history and evolution of science, pursuing the cheapest online history master's degree can enhance your understanding of scientific milestones and prepare you for careers in science policy, education, or research communication.

Additionally, for those considering work in academic or scientific libraries, it's helpful to know how much does it cost to become a librarian. A library science degree can position you in information management, archives, or research support roles within the scientific community.

Best Scientists Citing Christoph Borner

Trending Scientists

Recently Published Articles