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Biology and Biochemistry

D-Index
61
Citations
14306
World Ranking
11290
National Ranking
805

Overview

Irmgard Merfort is affiliated with the University of Freiburg in Germany. Their research output spans fields primarily in Biochemistry, Genetics and Molecular Biology as well as Medicine. The work encompasses multiple subfields, notably Molecular Biology, Surgery, Health, Toxicology and Mutagenesis, Pollution, and Physiology.

The scientist's research topics have covered diverse areas including:

  • Inflammasome and immune disorders
  • Cholesterol and Lipid Metabolism
  • Kawasaki Disease and Coronary Complications
  • Air Quality and Health Impacts
  • Energy and Environment Impacts
  • Heme Oxygenase-1 and Carbon Monoxide
  • Adenosine and Purinergic Signaling

Recent published papers featuring Irmgard Merfort include:

  • "Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases," 2021, Cell Death and Disease
  • "Particulate Matter (PM2.5) from Biomass Combustion Induces an Anti-Oxidative Response and Cancer Drug Resistance in Human Bronchial Epithelial BEAS-2B Cells," 2020, International Journal of Environmental Research and Public Health
  • "Blocking P2X purinoceptor 4 signalling alleviates cigarette smoke induced pulmonary inflammation," 2022, Respiratory Research
  • "Phosphodiesterases in the Liver as Potential Therapeutic Targets of Cirrhotic Portal Hypertension," 2020, International Journal of Molecular Sciences
  • "On the validity of fluorimetric intracellular calcium detection: Impact of lipid components," 2022, Biochemical and Biophysical Research Communications

Frequent coauthors collaborating with Irmgard Merfort include:

  • Paula M. Soriano-Teruel
  • Guillermo García-Laínez
  • María Marco-Salvador
  • Julián Pardo
  • Maykel Arias

Publications have appeared in several scientific venues, among them:

  • Cell Death and Disease
  • International Journal of Environmental Research and Public Health
  • Respiratory Research
  • International Journal of Molecular Sciences
  • Biochemical and Biophysical Research Communications

Best Publications

  • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

    Patricio Godoy;Nicola J. Hewitt;Ute Albrecht;Melvin E. Andersen

  • Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin.

    Günter Seelinger;Irmgard Merfort;Christoph M. Schempp

  • The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65

    G Lyss;A Knorre;T J Schmidt;H L Pahl

  • Cysteine 38 in p65/NF-κB Plays a Crucial Role in DNA Binding Inhibition by Sesquiterpene Lactones

    Alfonso J. Garcı́a-Piñeres;Vı́ctor Castro;Gerardo Mora;Thomas J. Schmidt

  • Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts.

    M. Fronza;B. Heinzmann;M. Hamburger;S. Laufer

  • Anti-carcinogenic Effects of the Flavonoid Luteolin

    Günter Seelinger;Irmgard Merfort;Ute Wölfle;Christoph M. Schempp

  • Inhibition of transcription factor NF-κB by sesquiterpene lactones: a proposed molecular mechanism of action

    Peter Rüngeler;Victor Castro;Gerardo Mora;Nezhun Gören

  • Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB

    Guido Lyss;Thomas J. Schmidt;Irmgard Merfort;Heike L. Pahl

  • Perspectives on Sesquiterpene Lactones in Inflammation and Cancer

    Irmgard Merfort

  • NMR spectral analysis of polyphenols from Punica granatum

    Mahmoud A.M. Nawwar;Sahar A.M. Hussein;Irmgard Merfort

  • ON/OFF and Beyond - A Boolean Model of Apoptosis

    Rebekka Schlatter;Kathrin Schmich;Ima Avalos Vizcarra;Ima Avalos Vizcarra;Peter Scheurich

  • Botanicals in dermatology: an evidence-based review.

    Juliane Reuter;Irmgard Merfort;Christoph M. Schempp

  • Cytotoxicity and genotoxicity of size-fractionated iron oxide (magnetite) in A549 human lung epithelial cells: role of ROS, JNK, and NF-κB.

    Mathias Könczöl;Sandra Ebeling;Ella Goldenberg;Fabian Treude

  • Altitudinal variation of secondary metabolite profiles in flowering heads of Arnica montana cv. ARBO.

    Renate Spitaler;P. Daniel Schlorhaufer;Ernst P. Ellmerer;Irmgard Merfort

  • Biological studies on Brazilian plants used in wound healing

    C. Schmidt;M. Fronza;M. Goettert;F. Geller

  • Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae).

    José L Aguilar;Percy Rojas;Adolfo Marcelo;Alberto Plaza

  • Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential

    A.J Garcı́a-Piñeres;M.T Lindenmeyer;I Merfort

  • Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages

    Eun Myoung Shin;Hong Yu Zhou;Hong Yu Zhou;Lian Yu Guo;Jeong Ah Kim

  • Tannins from the leaves of Punica granatum

    Sahar A.M. Hussein;Heba H. Barakat;Irmgard Merfort;Mahmoud A.M. Nawwar

  • In vitro studies to evaluate the wound healing properties of Calendula officinalis extracts.

    Christoph Nicolaus;Susanne Junghanns;Anja Hartmann;Renato Murillo

Frequent Co-Authors

Stefan Laufer
Stefan Laufer University of Tübingen
Christoph Borner
Christoph Borner University of Freiburg
Oliver Sawodny
Oliver Sawodny University of Stuttgart
Felix Kratz
Felix Kratz University of Florence
Reto Gieré
Reto Gieré University of Pennsylvania
Victor Wray
Victor Wray Heinrich Heine University Düsseldorf
Jan G. Hengstler
Jan G. Hengstler TU Dortmund University
Rolf Gebhardt
Rolf Gebhardt Leipzig University
Lúcia Helena Faccioli
Lúcia Helena Faccioli Universidade de São Paulo
Verena M. Dirsch
Verena M. Dirsch University of Vienna

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