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Chemistry

D-Index
60
Citations
13519
World Ranking
9656
National Ranking
286

Overview

Felix Kratz is affiliated with the University of Florence in Italy and has contributed to research primarily in the fields of Engineering and Biochemistry, Genetics, and Molecular Biology. Their work extends into subfields such as Biomedical Engineering, Condensed Matter Physics, Pulmonary and Respiratory Medicine, Cell Biology, and Biophysics.

Their research covers a range of topics, including:

  • Microfluidic and Bio-sensing Technologies
  • Micro and Nano Robotics
  • Molecular Communication and Nanonetworks
  • Cellular Mechanics and Interactions
  • Cell Image Analysis Techniques
  • 3D Printing in Biomedical Research
  • Connective Tissue Disorders Research

Kratz has published regularly in several scientific venues. The most frequent publication venues include:

  • Biophysical Journal
  • Soft Matter
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Langmuir

Notable recent publications by Felix Kratz include:

  • Enhancing robustness, precision, and speed of traction force microscopy with machine learning, 2023, Biophysical Journal
  • Chemotactic migration of bacteria in porous media, 2021, Biophysical Journal
  • Cell-Penetrating Doxorubicin Released from Elastin-Like Polypeptide Kills Doxorubicin-Resistant Cancer Cells in In Vitro Study, 2021, International Journal of Molecular Sciences
  • Pressure-deformation relations of elasto-capillary drops (droploons) on capillaries, 2021, Soft Matter
  • Chemotactic Migration of Bacteria in Porous Media, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Kratz include:

  • Jan Kierfeld
  • Sujit S. Datta
  • Tapomoy Bhattacharjee
  • Daniel B. Amchin
  • Jenna Ott

Best Publications

  • Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

    Unknown

  • Polymer Therapeutics: Concepts and Applications

    Rainer Haag;Felix Kratz

  • Impact of albumin on drug delivery — New applications on the horizon

    Unknown

  • Prodrug strategies in anticancer chemotherapy.

    Felix Kratz;Ivonne A. Müller;Claudia Ryppa;André Warnecke

  • Probing the Cysteine-34 Position of Endogenous Serum Albumin with Thiol-Binding Doxorubicin Derivatives. Improved Efficacy of an Acid-Sensitive Doxorubicin Derivative with Specific Albumin-Binding Properties Compared to That of the Parent Compound

    Felix Kratz;André Warnecke;Karin Scheuermann;Cornelia Stockmar

  • A clinical update of using albumin as a drug vehicle — A commentary

    Felix Kratz

  • Clinical impact of serum proteins on drug delivery

    Unknown

  • Drug-polymer conjugates containing acid-cleavable bonds.

    Felix Kratz;Ulrich Beyer;Mark Thomas Schutte

  • A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.

    Ahmed M. Mansour;Joachim Drevs;Norbert Esser;Farid M. Hamada

  • Transferrin Conjugates of Doxorubicin: Synthesis, Characterization, Cellular Uptake, and in Vitro Efficacy

    Felix Kratz;Ulrich Beyer;Thomas Roth;Nadya Tarasova

  • Serum proteins as drug carriers of anticancer agents: a review.

    Felix Kratz;Ulrich Beyer

  • A novel macromolecular prodrug concept exploiting endogenous serum albumin as a drug carrier for cancer chemotherapy.

    Felix Kratz;Ralph Müller-Driver;Inga Hofmann;Joachim Drevs

  • A facile approach for dual-responsive prodrug nanogels based on dendritic polyglycerols with minimal leaching

    Xuejiao Zhang;Katharina Achazi;Dirk Steinhilber;Felix Kratz

  • Finding the optimal balance: Challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems

    Felix Kratz;André Warnecke

  • Binding of ruthenium(III) anti-tumor drugs to human lactoferrin probed by high resolution X-ray crystallographic structure analyses

    Clyde A. Smith;Andrew J. Sutherland-Smith;Felix Kratz;E. N. Baker

  • Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.

    Björn Schmid;Da-Eun Chung;André Warnecke;Iduna Fichtner

  • DOXO-EMCH (INNO-206): the first albumin-binding prodrug of doxorubicin to enter clinical trials

    Unknown

  • Acid-sensitive polyethylene glycol conjugates of doxorubicin: preparation, in vitro efficacy and intracellular distribution

    Paula C.A. Rodrigues;Ulrich Beyer;Peter Schumacher;Thomas Roth

  • Polyethylene glycol conjugates of methotrexate varying in their molecular weight from MW 750 to MW 40000: synthesis, characterization, and structure-activity relationships in vitro and in vivo

    Katja Riebeseel;Elfi Biedermann;Roland Löser;Norbert Breiter

  • Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell

    Marcelo Calderón;Pia Welker;Kai Licha;Iduna Fichtner

  • Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy.

    André Warnecke;Felix Kratz

  • Development of Novel Bisphosphonate Prodrugs of Doxorubicin for Targeting Bone Metastases That Are Cleaved pH Dependently or by Cathepsin B: Synthesis, Cleavage Properties, and Binding Properties to Hydroxyapatite As Well As Bone Matrix

    Katrin Hochdörffer;Khalid Abu Ajaj;Cynthia Schäfer-Obodozie;Felix Kratz

  • Development of enzymatically cleavable prodrugs derived from dendritic polyglycerol.

    Marcelo Calderón;Ralph Graeser;Felix Kratz;Rainer Haag

  • Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates

    Felix Kratz;Joachim Drevs;Gerlinde Bing;Cornelia Stockmar

  • Development of pH-responsive core–shell nanocarriers for delivery of therapeutic and diagnostic agents

    Shangjie Xu;Ying Luo;Ralph Graeser;André Warnecke

  • Prodrug Strategies in Anticancer Chemotherapy

    Felix Kratz;Ivonne A. Mueller;Claudia Ryppa;Andre Warnecke

Frequent Co-Authors

Rainer Haag
Rainer Haag Freie Universität Berlin
Marcelo Calderón
Marcelo Calderón University of the Basque Country
Rolf Mülhaupt
Rolf Mülhaupt University of Freiburg
Luigi Messori
Luigi Messori University of Florence
Irmgard Merfort
Irmgard Merfort University of Freiburg
Bernhard K. Keppler
Bernhard K. Keppler University of Vienna
Manfred Jung
Manfred Jung University of Freiburg
Kurt E. Geckeler
Kurt E. Geckeler Gwangju Institute of Science and Technology
Annette G. Beck-Sickinger
Annette G. Beck-Sickinger Leipzig University
Barbara Rothen-Rutishauser
Barbara Rothen-Rutishauser University of Fribourg

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