Tomáš Etrych

Best Publications

• In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

  Geoffrey M Lynn;Geoffrey M Lynn;Richard Laga;Richard Laga;Patricia A Darrah;Andrew S Ishizuka

  441
  Citations

• New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties.

  Tomas Etrych;Markéta Jelinkova;Blanka Rihova;Karel Ulbrich

  433
  Citations

• Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin.

  Marina Talelli;Maryam Iman;Amir K. Varkouhi;Cristianne J.F. Rijcken

  297
  Citations

• HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity.

  K. Ulbrich;T. Etrych;P. Chytil;M. Jelinkova

  256
  Citations

• Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy.

  Tomáš Etrych;Lubomír Kovář;Jiří Strohalm;Petr Chytil

  199
  Citations

• N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation.

  Petr Chytil;Tomáš Etrych;Jaroslav Kříž;Vladimír Šubr

  180
  Citations

• Synthesis of HPMA Copolymers Containing Doxorubicin Bound via a Hydrazone Linkage. Effect of Spacer on Drug Release and in vitro Cytotoxicity

  Tomáš Etrych;Petr Chytil;Markéta Jelínková;Blanka Říhová

  174
  Citations

• N-(2-Hydroxypropyl)methacrylamide-Based Polymer Conjugates with pH-Controlled Activation of Doxorubicin. I. New Synthesis, Physicochemical Characterization and Preliminary Biological Evaluation

  Tomáš Etrych;Tomáš Mrkvan;Petr Chytil;Čestmír Koňák

  166
  Citations

• Nanomedicines for Inflammatory Arthritis: Head-to-Head Comparison of Glucocorticoid-Containing Polymers, Micelles, and Liposomes

  Lingdong Quan;Yijia Zhang;Bart J Crielaard;Anand Dusad

  165
  Citations

• New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting

  P. Chytil;T. Etrych;Č. Koňák;M. Šírová

  164
  Citations

• Fluorescence optical imaging in anticancer drug delivery

  Unknown

  160
  Citations

• Antibody-targeted polymer-doxorubicin conjugates with pH-controlled activation.

  Ulbrich K;Etrych T;Chytil P;Jelínková M

  159
  Citations

• Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers.

  Twan Lammers;Twan Lammers;Rainer Kühnlein;Maria Kissel;Vladimir Subr

  155
  Citations

• HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity.

  Tomáš Etrych;Vladimír Šubr;Jiří Strohalm;Milada Šírová

  154
  Citations

• HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release.

  Tomáš Etrych;Milada Šírová;L. Starovoytova;Blanka Říhová

  151
  Citations

• Polymer‐coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction

  Robert C. Carlisle;Tomas Etrych;Simon S. Briggs;Jon A. Preece

  147
  Citations

• Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy

  M. Talelli;S. Oliveira;C.J. Rijcken;E.H. Pieters

  142
  Citations

• Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage

  Hideaki Nakamura;Tomas Etrych;Petr Chytil;Manami Ohkubo

  140
  Citations

• Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes.

  B. R̆ı́hová;T. Etrych;M. Pechar;M. Jelı́nková

  139
  Citations

• HPMA-based polymer conjugates with drug combination.

  Hana Krakovičová;Tomáš Etrych;Karel Ulbrich

  131
  Citations