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Jindřich Kopeček

Jindřich Kopeček

D-Index & Metrics

Chemistry

D-Index
108
Citations
38832
World Ranking
883
National Ranking
350

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors
  • 2011 - Member of the National Academy of Engineering For contributions to the design of hydrogel biomaterials and polymeric drug delivery systems.
  • 1995 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Jindřich Kopeček is affiliated with the University of Utah in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with a notable emphasis on Oncology and Immunology as subfields. The scientist's work encompasses molecular biology, radiology, nuclear medicine and imaging, and biomedical engineering, highlighting a multidisciplinary approach to biomedical research.

Their research topics include CAR-T cell therapy research, immunotherapy and immune responses, monoclonal and polyclonal antibodies research, RNA interference and gene delivery, cancer immunotherapy and biomarkers, immune cell function and interaction, and nanoplatforms for cancer theranostics.

Jindřich Kopeček has published extensively in prominent scientific journals. Frequent publication venues include:

  • Journal of Controlled Release
  • Macromolecular Bioscience
  • Advanced Drug Delivery Reviews
  • Advanced Functional Materials
  • Acta Biomaterialia

Recent papers associated with or closely linked to Kopeček's research include:

  • Polymer nanomedicines, 2020, Advanced Drug Delivery Reviews
  • Inhibition of Immunosuppressive Tumors by Polymer-Assisted Inductions of Immunogenic Cell Death and Multivalent PD-L1 Crosslinking, 2020, Advanced Functional Materials
  • Nanomedicines in B cell-targeting therapies, 2021, Acta Biomaterialia
  • Combination treatment with immunogenic and anti-PD-L1 polymer-drug conjugates of advanced tumors in a transgenic MMTV-PyMT mouse model of breast cancer, 2021, Journal of Controlled Release
  • Dendronized polymer conjugates with amplified immunogenic cell death for oncolytic immunotherapy, 2020, Journal of Controlled Release

The scientist frequently collaborates with peers including Jiyuan Yang, M. Tommy Gambles, Douglas W. Sborov, Jiawei Wang, and Paul J. Shami, indicative of a collaborative research network.

In recognition of their contributions, Jindřich Kopeček has received several awards such as:

  • Fellow, National Academy of Inventors (2018)
  • Member of the National Academy of Engineering (2011) for contributions to the design of hydrogel biomaterials and polymeric drug delivery systems
  • Fellow of the Indian National Academy of Engineering (INAE) (1995)

Best Publications

  • Diverse Applications of Nanomedicine

    Beatriz Pelaz;Christoph Alexiou;Ramon A. Alvarez-Puebla;Frauke Alves;Frauke Alves

  • Hydrogel biomaterials: A smart future?

    Jindřich Kopeček

  • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

    Thomas Merdan;Jindrich Kopec̆ek;Thomas Kissel

  • Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains

    Chun Wang;Russell J. Stewart;JindŘich KopeČek

  • Protein-resistant surfaces prepared by PEO-containing block copolymer surfactants.

    Jin Ho Lee;Jindrich Kopecek;Joseph D. Andrade

  • HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action.

    Jindřich Kopeček;Pavla Kopečková;Tamara Minko;Zheng Rong Lu

  • HPMA copolymers: origins, early developments, present, and future.

    Jindřich Kopeček;Pavla Kopečková

  • Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

    L. W. Seymour;R. Duncan;J. Strohalm;Jindrich Kopecek

  • Hydrogels as smart biomaterials

    Jindřich Kopeček;Jiyuan Yang

  • Soluble synthetic polymers as potential drug carriers

    Ruth Duncan;Jindřich Kopeček

  • Hydrogels: From soft contact lenses and implants to self‐assembled nanomaterials

    Jindrich Kopecek

  • Polymer conjugates with anticancer activity

    D. Putnam;J. Kopeček

  • Smart and genetically engineered biomaterials and drug delivery systems

    Jindřich Kopeček

  • Polymer – drug conjugates: Origins, progress to date and future directions

    Jindřich Kopeček

  • Intracellular targeting of polymer-bound drugs for cancer chemotherapy.

    Aparna Nori;Jindřich Kopeček

  • Poly[N-(2-hydroxypropyl)methacrylamide]—I. Radical polymerization and copolymerization

    Jindrich Kopecek;H. Baẑilová

  • Polymers containing enzymatically degradable bonds, 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B

    Pavla Rejmanová;Jindřich Kopeček;Jan Pohl;Miroslav Baudyš

  • Smart self-assembled hybrid hydrogel biomaterials.

    Jindřich Kopeček;Jiyuan Yang

  • HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line.

    T. Minko;P. Kopečková;V. Pozharov;J. Kopeček

  • PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice

    Thomas Merdan;Klaus Kunath;Holger Petersen;Udo Bakowsky

  • Water soluble polymers in tumor targeted delivery.

    J Kopeček;P Kopečková;T Minko;Z.-R Lu

Frequent Co-Authors

Pavla Kopečková
Pavla Kopečková University of Utah
Ruth Duncan
Ruth Duncan Cardiff University
Karel Ulbrich
Karel Ulbrich Czech Academy of Sciences
Dong Wang
Dong Wang Peking University
Joseph D. Andrade
Joseph D. Andrade University of Utah
Karel Dušek
Karel Dušek Czech Academy of Sciences
Leonard W. Seymour
Leonard W. Seymour University of Oxford
Zhongwei Gu
Zhongwei Gu Sichuan University
Andre G. Skirtach
Andre G. Skirtach Ghent University
Maurizio Prato
Maurizio Prato University of Trieste

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