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Hiromitsu Kumada

Hiromitsu Kumada

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Microbiology
Japan
2026

D-Index & Metrics

Microbiology

D-Index
100
Citations
39139
World Ranking
402
National Ranking
9

Medicine

D-Index
103
Citations
41525
World Ranking
7328
National Ranking
178

Research.com Recognitions

  • 2026 - Research.com Microbiology in Japan Leader Award
  • 2025 - Research.com Microbiology in Japan Leader Award
  • 2023 - Research.com Microbiology in Japan Leader Award
  • 2022 - Research.com Microbiology in Japan Leader Award

Overview

Hiromitsu Kumada is affiliated with Fukuoka University in Japan and has an extensive record of research primarily in the field of medicine, with a specific focus on hepatology. Their work is strongly oriented towards the diagnosis, treatment, and prognosis of liver diseases, particularly hepatocellular carcinoma.

Their main fields of study include:

  • Medicine

Within this broad field, Kumada has contributed significantly to subfields such as:

  • Hepatology
  • Epidemiology
  • Oncology
  • Pulmonary and Respiratory Medicine
  • Endocrinology, Diabetes and Metabolism

Their research topics demonstrate specific interests in:

  • Liver Disease Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Liver Disease and Transplantation
  • Pancreatic and Hepatic Oncology Research
  • Cancer Immunotherapy and Biomarkers

Kumada's frequent collaborators include:

  • Fumitaka Suzuki
  • Tetsuya Hosaka
  • Norio Akuta
  • Yusuke Kawamura
  • Hitomi Sezaki

Their research has been published extensively in a range of venues, notably:

  • Hepatology Research
  • Oncology
  • Journal of Clinical Oncology
  • Internal Medicine
  • Journal of Gastroenterology

Recent representative papers authored or coauthored by Kumada include:

  • Phase Ib Study of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Hepatocellular Carcinoma, 2020, Journal of Clinical Oncology
  • Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial, 2023, The Lancet Oncology
  • Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease, 2022, Science Translational Medicine
  • A phase Ib study of lenvatinib (LEN) plus nivolumab (NIV) in patients (pts) with unresectable hepatocellular carcinoma (uHCC): Study 117., 2020, Journal of Clinical Oncology
  • A phase Ib study of lenvatinib (LEN) plus pembrolizumab (PEMBRO) in unresectable hepatocellular carcinoma (uHCC)., 2020, Journal of Clinical Oncology

Best Publications

  • Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma

    Yujin Hoshida;Augusto Villanueva;Masahiro Kobayashi;Judit Peix

  • Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma.

    Yujin Hoshida;Sebastian M.B. Nijman;Sebastian M.B. Nijman;Masahiro Kobayashi;Jennifer A. Chan;Jennifer A. Chan

  • Phase Ib Study of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Hepatocellular Carcinoma

    Richard S. Finn;Masafumi Ikeda;Andrew X. Zhu;Max W. Sung

  • Long‐term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection

    Tetsuya Hosaka;Fumitaka Suzuki;Masahiro Kobayashi;Yuya Seko

  • The long-term pathological evolution of chronic hepatitis C

    M Yano;H Kumada;M Kage;K Ikeda

  • Effects of Oral Branched-Chain Amino Acid Granules on Event-Free Survival in Patients With Liver Cirrhosis

    Yasutoshi Muto;Shunichi Sato;Akiharu Watanabe;Hisataka Moriwaki

  • Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma.

    Masatoshi Kudo;Kazuho Imanaka;Nobuyuki Chida;Kohei Nakachi

  • Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis.

    Kenji Ikeda;Satoshi Saitoh;Yasuji Arase;Kazuaki Chayama

  • Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection.

    Hiromitsu Kumada;Yoshiyuki Suzuki;Kenji Ikeda;Joji Toyota

  • Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients

    Kenji Ikeda;Satoshi Saitoh;Yoshiyuki Suzuki;Masahiro Kobayashi

  • A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians

    Yoichiro Kamatani;Sukanya Wattanapokayakit;Hidenori Ochi;Takahisa Kawaguchi

  • Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy

    Kazuaki Chayama;Yoshiyuki Suzuki;Masahiro Kobayashi;Mizuho Kobayashi

  • Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor—A prospective randomized study of hepatitis C virus–related liver cancer

    Kenji Ikeda;Yasuji Arase;Satoshi Saitoh;Masahiro Kobayashi

  • Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma.

    Augusto Villanueva;Augusto Villanueva;Yujin Hoshida;Yujin Hoshida;Carlo Battiston;Victoria Tovar;Victoria Tovar

  • Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b–infected null responders†‡§

    Kazuaki Chayama;Shoichi Takahashi;Joji Toyota;Yoshiyasu Karino

  • The long term efficacy of glycyrrhizin in chronic hepatitis C patients

    Unknown

  • Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma

    Shlomi Finkin;Detian Yuan;Ilan Stein;Koji Taniguchi

  • Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinoma.

    Kenji Ikeda;Masatoshi Kudo;Seiji Kawazoe;Yukio Osaki

  • Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: Amino acid substitutions in the core region and low-density lipoprotein cholesterol levels

    Norio Akuta;Fumitaka Suzuki;Yusuke Kawamura;Hiromi Yatsuji

  • Association of Amino Acid Substitution Pattern in Core Protein of Hepatitis C Virus Genotype 1b High Viral Load and Non-Virological Response to Interferon-Ribavirin Combination Therapy

    Norio Akuta;Fumitaka Suzuki;Hitomi Sezaki;Yoshiyuki Suzuki

  • Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin

    Norio Akuta;Fumitaka Suzuki;Miharu Hirakawa;Yusuke Kawamura

Frequent Co-Authors

Kenji Ikeda
Kenji Ikeda University of California, San Francisco
Yasuji Arase
Yasuji Arase University of Yamanashi
Masahiro Kobayashi
Masahiro Kobayashi Toranomon Hospital
Yoshiyuki Suzuki
Yoshiyuki Suzuki Fukushima Medical University
Fumitaka Suzuki
Fumitaka Suzuki Toranomon Hospital
Satoshi Saitoh
Satoshi Saitoh Toranomon Hospital
Tetsuya Hosaka
Tetsuya Hosaka Toranomon Hospital
Hitomi Sezaki
Hitomi Sezaki Toranomon Hospital
Mariko Kobayashi
Mariko Kobayashi Kaohsiung Medical University
Kazuaki Chayama
Kazuaki Chayama Hiroshima University

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