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Chemistry

D-Index
56
Citations
8775
World Ranking
11897
National Ranking
874

Overview

Thomas Schrader is affiliated with the University of Duisburg-Essen in Germany. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong emphasis on subfields such as Molecular Biology, Physiology, Spectroscopy, Neurology, and Epidemiology.

The scientist's work covers multiple topics including Alzheimer's disease research and treatments, Protein Structure and Dynamics, RNA and protein synthesis mechanisms, Parkinson's Disease Mechanisms and Treatments, Molecular Sensors and Ion Detection, Analytical Chemistry and Chromatography, and Cellular transport and secretion.

Thomas Schrader has contributed to numerous publications across a variety of venues. Frequent publication venues include the Journal of the American Chemical Society (4 publications), Biomacromolecules (3 publications), Nature Communications (2 publications), Chemical Communications (2 publications), and Molecular Therapy (2 publications).

Their recent papers include:

  • CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease, 2020, Nature Communications
  • Chirality sensing of terpenes, steroids, amino acids, peptides and drugs with acyclic cucurbitnurils and molecular tweezers, 2020, Chemical Communications
  • Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers, 2020, Journal of the American Chemical Society
  • The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease, 2020, Molecular Therapy
  • Specific inhibition of the Survivin-CRM1 interaction by peptide-modified molecular tweezers, 2021, Nature Communications

Among frequent coauthors collaborating with Thomas Schrader are Gal Bitan, Frank-Gerrit Klärner, Peter Bayer, Christine Beuck, and Ibrar Siddique.

Best Publications

  • Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

    Sharmistha Sinha;Dahabada H. J. Lopes;Zhenming Du;Eric S. Pang

  • A molecular tweezer for lysine and arginine.

    Michael Fokkens;Thomas Schrader;Frank-Gerrit Klärner

  • Aromatic interactions by molecular tweezers and clips in chemical and biological systems.

    Frank-Gerrit Klärner;Thomas Schrader

  • Molecular tweezers modulate 14-3-3 protein-protein interactions

    David Bier;Rolf Rose;Kenny Bravo-Rodriguez;Maria Bartel

  • Functional Synthetic Receptors

    Thomas Schrader;Andrew D. Hamilton

  • Molecular Clip and Tweezer Introduce New Mechanisms of Enzyme Inhibition

    Peter Talbiersky;Frank Bastkowski;Frank-Gerrit Klärner;Thomas Schrader

  • A Novel "Molecular Tweezer" Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo

    Shubhangi Prabhudesai;Sharmistha Sinha;Aida Attar;Aswani Kotagiri

  • Nanomolar protein sensing with embedded receptor molecules.

    Reza Zadmard;Thomas Schrader

  • Molecular Tweezers for Lysine and Arginine – Powerful Inhibitors of Pathologic Protein Aggregation

    Thomas Schrader;Gal Bitan;Frank-Gerrit Klärner

  • Color fingerprinting of proteins by calixarenes embedded in lipid/polydiacetylene vesicles.

    Sofiya Kolusheva;Reza Zadmard;Thomas Schrader;Raz Jelinek

  • A fluorescent polymeric heparin sensor.

    Wei Sun;Heinz Bandmann;Thomas Schrader

  • Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

    Luigi Ippolito;Alberto Marini;Lorenzo Cavallini;Andrea Morandi

  • Arginine- and lysine-specific polymers for protein recognition and immobilization.

    Christian Renner;Jacob Piehler;Thomas Schrader

  • Molecular Tweezer and Clip in Aqueous Solution: Unexpected Self-Assembly, Powerful Host−Guest Complex Formation, Quantum Chemical 1H NMR Shift Calculation

    Frank-Gerrit Klärner;Björn Kahlert;Anke Nellesen;Jan Zienau

  • Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01.

    Sharmistha Sinha;Zhenming Du;Panchanan Maiti;Frank-Gerrit Klärner

  • A color sensor for catecholamines.

    Michael Maue;Thomas Schrader

  • Prevention of Alzheimer's Disease-associated Aβ Aggregation by Rationally Designed Nonpeptidic β-Sheet Ligands

    Petra Rzepecki;Luitgard Nagel-Steger;Sophie Feuerstein;Uwe Linne

  • Selective Detection of Catecholamines by Synthetic Receptors Embedded in Chromatic Polydiacetylene Vesicles

    Sofiya Kolusheva;Oliver Molt;Michael Herm;Thomas Schrader

  • Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.

    Srabasti Acharya;Brian M. Safaie;Piriya Wongkongkathep;Magdalena I. Ivanova

  • Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers.

    Aida Attar;Cristian Ripoli;Elisa Riccardi;Panchanan Maiti

Frequent Co-Authors

Frank-Gerrit Klärner
Frank-Gerrit Klärner University of Duisburg-Essen
Gal Bitan
Gal Bitan University of California, Los Angeles
Dieter Willbold
Dieter Willbold Forschungszentrum Jülich
Detlev Riesner
Detlev Riesner Heinrich Heine University Düsseldorf
Joseph A. Loo
Joseph A. Loo University of California, Los Angeles
Edward C. Taylor
Edward C. Taylor Princeton University
Heinrich Sticht
Heinrich Sticht University of Erlangen-Nuremberg
Christian Ochsenfeld
Christian Ochsenfeld Ludwig-Maximilians-Universität München
Wolfgang Steglich
Wolfgang Steglich Ludwig-Maximilians-Universität München
Raz Jelinek
Raz Jelinek Ben-Gurion University of the Negev

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