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Chemistry

D-Index
64
Citations
16340
World Ranking
7971
National Ranking
173

Overview

Luc Brunsveld is affiliated with Eindhoven University of Technology in the Netherlands. Their research is concentrated primarily within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. The main subfields of their work include Molecular Biology, Pharmacology, Oncology, Materials Chemistry, and Spectroscopy.

The scientist's research topics cover multiple areas including 14-3-3 protein interactions, ubiquitin and proteasome pathways, microbial natural products and biosynthesis, RNA interference and gene delivery, advanced biosensing and bioanalysis techniques, estrogen and related hormone effects, and advanced proteomics techniques and applications.

Frequent coauthors collaborating with Luc Brunsveld include Christian Ottmann, Peter J. Cossar, Michelle R. Arkin, Emira J. Visser, and Volkher Scharnhorst.

Luc Brunsveld has published extensively in a selection of scientific journals. Among the frequent venues for their publications are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angewandte Chemie International Edition
  • Journal of the American Chemical Society
  • Angewandte Chemie
  • Chemical Science

Highlighted papers by Luc Brunsveld include:

  • "Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation," 2020, Nature Reviews Endocrinology
  • "Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome," 2020, Nature Catalysis
  • "Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions," 2020, Nature Communications
  • "Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering," 2020, Angewandte Chemie International Edition
  • "Supramolecular Nanoscaffolds within Cytomimetic Protocells as Signal Localization Hubs," 2020, Journal of the American Chemical Society

Best Publications

  • Reversible Polymers Formed from Self-Complementary Monomers Using Quadruple Hydrogen Bonding

    Rint P. Sijbesma;Felix H. Beijer;Felix H. Beijer;Luc Brunsveld;Luc Brunsveld;Brigitte J. B. Folmer;Brigitte J. B. Folmer

  • Helical self-assembled polymers from cooperative stacking of hydrogen-bonded pairs

    J.H.K.K. Hirschberg;L. Brunsveld;A. Ramzi;J.A.J.M. Vekemans

  • Modulators of Protein-Protein Interactions

    Lech-Gustav Lg Milroy;TN Grossmann;S Hennig;L Luc Brunsveld

  • Small-molecule inhibition of APT1 affects Ras localization and signaling

    Frank J Dekker;Oliver Rocks;Nachiket Vartak;Sascha Menninger

  • Combining supramolecular chemistry with biology

    Dana A. Uhlenheuer;Katja Petkau;Luc Brunsveld

  • Modulators of 14-3-3 Protein-Protein Interactions

    Loes M. Stevers;Eline Sijbesma;Maurizio Botta;Carol MacKintosh

  • Self-assembly of folded m-phenylene ethynylene oligomers into helical columns.

    Luc Brunsveld;E. W. Meijer;Ryan B. Prince;Jeffrey S. Moore

  • Hierarchical Growth of Chiral Self-Assembled Structures in Protic Media†

    L. Brunsveld;H. Zhang;M. Glasbeek;J.A.J.M. Vekemans

  • Twist Sense Bias Induced by Chiral Side Chains in Helically Folded Oligomers.

    Ryan B. Prince;Luc Brunsveld;E. W. Meijer;Jeffrey S. Moore

  • Therapeutic intervention based on protein prenylation and associated modifications

    Michael H Gelb;Lucas Brunsveld;Christine A Hrycyna;Susan Michaelis

  • Structure of Rab GDP-Dissociation Inhibitor in Complex with Prenylated YPT1 GTPase

    Alexey Rak;Olena Pylypenko;Thomas Durek;Anja Watzke

  • Hierarchical formation of helical supramolecular polymers via stacking of hydrogen-bonded pairs in water

    L. Brunsveld;J. A. J. M. Vekemans;J. H. K. K. Hirschberg;R. P. Sijbesma

  • Protein Dimerization Induced by Supramolecular Interactions with Cucurbit[8]uril

    Hoang D. Nguyen;Dung T. Dang;Joost L. J. Van Dongen;Luc Brunsveld

  • Determination of dabigatran, rivaroxaban and apixaban by ultra‐performance liquid chromatography – tandem mass spectrometry (UPLC‐MS/MS) and coagulation assays for therapy monitoring of novel direct oral anticoagulants

    E Ellen Schmitz;K Koen Boonen;van den Dja Heuvel;van Jlj Joost Dongen

  • Chiral Amplification in Columns of Self-Assembled N, N', N"-Tris((S)-3, 7-dimethyloctyl)benzene-1, 3, 5-tricarboxamide in Dilute Solution

    L. Brunsveld;A.P.H.J. Schenning;M.A.C. Broeren;H.M. Janssen

  • Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow

    A Ali Talla;B Driessen;Njw Natan Straathof;Lech-Gustav Lg Milroy

  • Supramolecular Chemistry Targeting Proteins.

    Sam van Dun;Christian Ottmann;Lech-Gustav Milroy;Luc Brunsveld

  • Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

    Karolien De Bosscher;Sofie J Desmet;Dorien Clarisse;Eva Estébanez-Perpiña

  • Stabilization of protein-protein interactions in drug discovery

    Sebastian A. Andrei;Eline Sijbesma;Michael Hann;Jeremy Davis

  • Lipidated Ras and Rab Peptides and Proteins—Synthesis, Structure, and Function

    Luc Brunsveld;Jürgen Kuhlmann;Kirill Alexandrov;Alfred Wittinghofer

  • Bioactivity-guided mapping and navigation of chemical space

    Steffen Renner;Willem A L van Otterlo;Marta Dominguez Seoane;Sabine Möcklinghoff

Frequent Co-Authors

Herbert Waldmann
Herbert Waldmann Max Planck Society
Pascal Jonkheijm
Pascal Jonkheijm University of Twente
Kirill Alexandrov
Kirill Alexandrov Queensland University of Technology
Rint P. Sijbesma
Rint P. Sijbesma Eindhoven University of Technology
Jurriaan Huskens
Jurriaan Huskens University of Twente
Roger S. Goody
Roger S. Goody Max Planck Society
Isabelle Landrieu
Isabelle Landrieu University of Lille
Albertus P. H. J. Schenning
Albertus P. H. J. Schenning Eindhoven University of Technology
Jeffrey S. Moore
Jeffrey S. Moore University of Illinois at Urbana-Champaign
Maarten Merkx
Maarten Merkx Eindhoven University of Technology

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