D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 46 Citations 7,753 142 World Ranking 12402 National Ranking 350

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

His primary scientific interests are in Biochemistry, Rab, Cell biology, GTPase and Prenylation. Many of his studies involve connections with topics such as Protozoa and Biochemistry. His Rab research incorporates elements of Transport protein, In vitro and Protein folding.

His work on GTP-binding protein regulators, Caveolin and Janus kinase as part of general Cell biology research is frequently linked to Immunoelectron microscopy and JAK-STAT signaling pathway, bridging the gap between disciplines. His GTPase study incorporates themes from Ras superfamily, GTP' and Guanine Nucleotide Dissociation Inhibitors. Kirill Alexandrov has included themes like Covalent bond, Thiol-ene reaction, Vesicular transport protein and Transferase in his Prenylation study.

His most cited work include:

  • GTPase activity of Rab5 acts as a timer for endocytic membrane fusion (290 citations)
  • Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. (268 citations)
  • Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. (246 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Cell biology, Rab, Prenylation and GTPase are his primary areas of study. His studies in Plasma protein binding, Amino acid, Protein engineering, Geranylgeranyl Transferase and Farnesyltransferase are all subfields of Biochemistry research. His work in Cell biology covers topics such as In vitro which are related to areas like In vivo.

His Rab research includes elements of Transport protein, Geranylgeranyl pyrophosphate, Vesicular transport protein, Ternary complex and Protein structure. His research links Stereochemistry with Prenylation. In his study, GTP-binding protein regulators is strongly linked to GTP', which falls under the umbrella field of GTPase.

He most often published in these fields:

  • Biochemistry (40.18%)
  • Cell biology (37.44%)
  • Rab (30.14%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (37.44%)
  • Biochemistry (40.18%)
  • Biosensor (8.68%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Biochemistry, Biosensor, Glucose dehydrogenase and Computational biology. His Cell biology study combines topics from a wide range of disciplines, such as Interleukin 18, Cytokine and Toll-like receptor. Kirill Alexandrov integrates Biochemistry with Striga hermonthica in his research.

His Biosensor study integrates concerns from other disciplines, such as Rational design, Analyte and Enzyme. His Protein prenylation study combines topics in areas such as GTPase, Pharmacology and Monocyte. Kirill Alexandrov interconnects Cell culture, In vitro and Prenylation in the investigation of issues within Rab.

Between 2014 and 2021, his most popular works were:

  • Synthetic protein switches: design principles and applications (81 citations)
  • Performance benchmarking of four cell‐free protein expression systems (34 citations)
  • Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems. (33 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Kirill Alexandrov focuses on Protein engineering, Biochemistry, Cell biology, Protein biosynthesis and Interactome. The various areas that he examines in his Protein engineering study include Protease, Nanotechnology and Synthetic biology. His work carried out in the field of Cell biology brings together such families of science as Proinflammatory cytokine and Innate immune system.

His research integrates issues of Amino acid and Translation, Sense Codon in his study of Protein biosynthesis. His research in Interactome intersects with topics in Signal transduction and Caveolae. His Caveolae research is multidisciplinary, relying on both Biogenesis, Endosome and Phosphorylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

Vladimir Rybin;Oliver Ullrich;Mariantonietta Rubino;Kirill A. Alexandrov.
Nature (1996)

373 Citations

Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins.

Oliver Ullrich;Harald Stenmark;Kirill Alexandrov;Lukas A Huber.
Journal of Biological Chemistry (1993)

373 Citations

Mechanism of activation of protein kinase JAK2 by the growth hormone receptor.

Andrew J. Brooks;Wei Dai;Megan L. O’Mara;Daniel Abankwa.
Science (2014)

313 Citations

RAB ESCORT PROTEIN-1 IS A MULTIFUNCTIONAL PROTEIN THAT ACCOMPANIES NEWLY PRENYLATED RAB PROTEINS TO THEIR TARGET MEMBRANES

Kirill Alexandrov;Hisanori Horiuchi;Olivia Steele-Mortimer;Miguel C. Seabra.
The EMBO Journal (1994)

310 Citations

Structure of Rab GDP-Dissociation Inhibitor in Complex with Prenylated YPT1 GTPase

Alexey Rak;Olena Pylypenko;Thomas Durek;Anja Watzke.
Science (2003)

242 Citations

The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP

Ana C. Carrera;Kirill Alexandrov;Thomas M. Roberts.
Proceedings of the National Academy of Sciences of the United States of America (1993)

226 Citations

Structural and thermodynamic analysis of the GFP:GFP-nanobody complex

Marta H. Kubala;Oleksiy Kovtun;Kirill Alexandrov;Brett M. Collins.
Protein Science (2010)

219 Citations

Diels-Alder ligation and surface immobilization of proteins.

Aline Dantas de Araújo;Jose M. Palomo;Janina Cramer;Maja Köhn.
Angewandte Chemie (2006)

188 Citations

Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease.

Alexey Rak;Olena Pylypenko;Anca Niculae;Konstantin Pyatkov.
Cell (2004)

181 Citations

Non-pathogenic trypanosomatid protozoa as a platform for protein research and production

Reinhard Breitling;Susanne Klingner;Nico Callewaert;Regina Pietrucha.
Protein Expression and Purification (2002)

176 Citations

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