What is he best known for?
The fields of study he is best known for:
- Enzyme
- Cell membrane
- Amino acid
Brett M. Collins mainly investigates Cell biology, Endosome, VPS29, Retromer and Sorting nexin.
His Cell biology study integrates concerns from other disciplines, such as Endocytic cycle and Clathrin.
His Endocytic cycle study combines topics in areas such as Signal transducing adaptor protein and Transmembrane protein.
In his research on the topic of Endosome, WASH complex is strongly related with Endocytosis.
As part of one scientific family, he deals mainly with the area of VPS29, narrowing it down to issues related to the VPS35, and often Cathepsin D, VPS26A and Heterotrimeric G protein.
Brett M. Collins studies SNX27 which is a part of Sorting nexin.
His most cited work include:
- Molecular Architecture and Functional Model of the Endocytic AP2 Complex (484 citations)
- Adaptors for clathrin coats: structure and function. (377 citations)
- A Large-Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the AP2 Clathrin Adaptor Complex (258 citations)
What are the main themes of his work throughout his whole career to date?
Brett M. Collins mainly focuses on Cell biology, Endosome, Sorting nexin, Retromer and Biophysics.
Brett M. Collins works mostly in the field of Cell biology, limiting it down to concerns involving Transmembrane protein and, occasionally, Structural biology.
His study on Endosome also encompasses disciplines like
- Endocytic cycle which is related to area like Clathrin,
- Protein structure together with Protein–protein interaction.
His Biophysics research incorporates elements of Membrane, Biochemistry and Plasma protein binding.
The concepts of his Plasma protein binding study are interwoven with issues in Exocytosis and Syntaxin.
His Transport protein research is multidisciplinary, relying on both Isothermal titration calorimetry and GTPase-activating protein.
He most often published in these fields:
- Cell biology (67.11%)
- Endosome (26.97%)
- Sorting nexin (20.39%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (67.11%)
- Endosome (26.97%)
- Biophysics (12.50%)
In recent papers he was focusing on the following fields of study:
Cell biology, Endosome, Biophysics, Membrane and Caveolae are his primary areas of study.
He regularly ties together related areas like BAR domain in his Cell biology studies.
His studies deal with areas such as Transmembrane protein and Peripheral membrane protein as well as Endosome.
As part of the same scientific family, Brett M. Collins usually focuses on Biophysics, concentrating on Exocytosis and intersecting with Vesicle and VAMP2.
His Membrane research is multidisciplinary, incorporating elements of Nuclear magnetic resonance spectroscopy and Peptide.
His work on Cavin as part of general Caveolae research is often related to Morphogenesis, thus linking different fields of science.
Between 2018 and 2021, his most popular works were:
- Neuropilin-1 is a host factor for SARS-CoV-2 infection. (220 citations)
- Towards a molecular understanding of endosomal trafficking by Retromer and Retriever (53 citations)
- Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. (42 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Cell membrane
- Amino acid
His primary scientific interests are in Cell biology, Sorting nexin, Transmembrane protein, Endosome and Retromer.
When carried out as part of a general Cell biology research project, his work on Homeostasis is frequently linked to work in PAS domain, therefore connecting diverse disciplines of study.
Brett M. Collins interconnects Lipogenesis, Cytoplasm, VPS29, Crosstalk and Retromer complex in the investigation of issues within Sorting nexin.
His Transmembrane protein study combines topics from a wide range of disciplines, such as BAR domain, A-site, Sorting Nexins, Endocytosis and Peripheral membrane protein.
With his scientific publications, his incorporates both Endosome and Biogenesis.
His work deals with themes such as Compartment, ESCRT, Endocytic recycling and Endosomal transport, which intersect with Retromer.
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