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Daniel D. Billadeau

Daniel D. Billadeau

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
23756
World Ranking
2745
National Ranking
1419

Overview

Daniel D. Billadeau is affiliated with the Mayo Clinic in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans several specialized subfields including molecular biology, immunology, cell biology, oncology, and cancer research.

Their research covers multiple key scientific topics, notably cellular transport and secretion, immune cell function and interaction, pancreatic and hepatic oncology research, cancer in relation to hypoxia and metabolism, epigenetics and DNA methylation, T-cell and B-cell immunology, and the use of CRISPR and genetic engineering techniques.

Billadeau has published numerous papers, with prominent examples including:

  • Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis, 2023, Nature Cell Biology
  • Mechanism of cargo recognition by retromer-linked SNX-BAR proteins, 2020, PLoS Biology
  • Endosome-to-TGN Trafficking: Organelle-Vesicle and Organelle-Organelle Interactions, 2020, Frontiers in Cell and Developmental Biology
  • NKG7 Is a T-cell-Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy, 2021, Cancer Immunology Research
  • Correction: Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-mediated DNA Damage Response, 2021, Clinical Cancer Research

The frequent venues where Billadeau has published include Frontiers in Cell and Developmental Biology, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancer Research, and the Proceedings of the National Academy of Sciences. These outlets indicate a focus on cellular and molecular mechanisms as well as cancer biology.

Billadeau has collaborated with several researchers regularly, demonstrating a network of co-authors that include Da Jia, Hyoungjun Ham, Ezra Burstein, Amika Singla, and Yong Xin. These collaborations have likely contributed to interdisciplinary approaches in their research fields.

Best Publications

  • A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

    Timothy S. Gomez;Daniel D. Billadeau

  • Structure and control of the actin regulatory WAVE complex

    Zhucheng Chen;Dominika Borek;Shae B. Padrick;Timothy S. Gomez

  • Regulation of T-cell activation by the cytoskeleton

    Daniel D. Billadeau;Jeffrey C. Nolz;Timothy S. Gomez

  • NKG2D-DAP10 triggers human NK cell–mediated killing via a Syk-independent regulatory pathway

    Daniel D Billadeau;Jadee L Upshaw;Renee A Schoon;Christopher J Dick

  • Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells

    Andrei V. Ougolkov;Martin E. Fernandez-Zapico;Doris N. Savoy;Raul A. Urrutia

  • VAV proteins as signal integrators for multi-subunit immune-recognition receptors.

    Martin Turner;Daniel D. Billadeau

  • Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

    Kerrie E. McNally;Rebecca Faulkner;Florian Steinberg;Matthew Gallon

  • SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

    M Herreros-Villanueva;J-S Zhang;A Koenig;A Koenig;E V Abel

  • Vav1 Dephosphorylation by the Tyrosine Phosphatase SHP-1 as a Mechanism for Inhibition of Cellular Cytotoxicity

    Christopher C. Stebbins;Carsten Watzl;Daniel D. Billadeau;Paul J. Leibson

  • Deregulated GSK3β activity in colorectal cancer: Its association with tumor cell survival and proliferation

    Abbas Shakoori;Andrei Ougolkov;Andrei Ougolkov;Zhi Wei Yu;Bin Zhang

  • NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells

    Jadee L Upshaw;Laura N Arneson;Renee A Schoon;Christopher J Dick

  • Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse.

    Timothy S. Gomez;Karan Kumar;Ricardo B. Medeiros;Yoji Shimizu

  • Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial

    P Liu;T Leong;L Quam;D Billadeau

  • Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6.

    Alan P. Kozikowski;Subhasish Tapadar;Doris N. Luchini;Ki Hwan Kim

  • The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell.

    D Billadeau;G Ahmann;P Greipp;B Van Ness

  • The WAVE2 Complex Regulates Actin Cytoskeletal Reorganization and CRAC-Mediated Calcium Entry during T Cell Activation

    Jeffrey C. Nolz;Timothy S. Gomez;Peimin Zhu;Shuixing Li

  • ITAMs versus ITIMs: striking a balance during cell regulation

    Daniel D. Billadeau;Paul J. Leibson

  • HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.

    Timothy S. Gomez;Sean D. McCarney;Esteban Carrizosa;Christine M. Labno

  • Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination

    Yi Heng Hao;Jennifer M. Doyle;Saumya Ramanathan;Timothy S. Gomez

  • Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

    Martin E. Fernandez-Zapico;Natalia C. Gonzalez-Paz;Ellen Weiss;Doris N. Savoy

Frequent Co-Authors

Paul J. Leibson
Paul J. Leibson Mayo Clinic
Raul Urrutia
Raul Urrutia Medical College of Wisconsin
Michael K. Rosen
Michael K. Rosen The University of Texas Southwestern Medical Center
Zhenkun Lou
Zhenkun Lou Mayo Clinic
Janis K. Burkhardt
Janis K. Burkhardt University of Pennsylvania
Jens T. Siveke
Jens T. Siveke German Cancer Research Center
Thomas C. Smyrk
Thomas C. Smyrk Mayo Clinic
Mark A. McNiven
Mark A. McNiven Mayo Clinic

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