World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
13808
World Ranking
11313
National Ranking
808

Overview

Jens T. Siveke is affiliated with the German Cancer Research Center in Germany and has a significant body of work focused primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research prominently addresses various aspects of oncology, particularly pancreatic and hepatic oncology, cancer genomics, and diagnostics.

Their recent scientific contributions include several publications, notable among them:

  • Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer, 2023, published in Nature
  • Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers, 2021, published in Cancer Discovery
  • The Latest Developments in Imaging of Fibroblast Activation Protein, 2020, published in Journal of Nuclear Medicine
  • Nab-paclitaxel plus gemcitabine versus nab-paclitaxel plus gemcitabine followed by FOLFIRINOX induction chemotherapy in locally advanced pancreatic cancer (NEOLAP-AIO-PAK-0113): a multicentre, randomised, phase 2 trial, 2020, published in The Lancet. Gastroenterology & Hepatology
  • CellViT: Vision Transformers for precise cell segmentation and classification, 2024, published in Medical Image Analysis

Siveke has collaborated extensively with several frequent co-authors, including:

  • Martin Schüler
  • Rainer Hamacher
  • Marija Trajkovic-Arsic
  • Wolfgang P. Fendler
  • Stefan Kasper

Their publications appear repeatedly in several key scientific venues, which include:

  • Journal of Nuclear Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of Oncology
  • Journal of Clinical Oncology
  • ESMO Open

Jens T. Siveke's research spans important subfields such as Oncology, Cancer Research, Molecular Biology, Pulmonary and Respiratory Medicine, and Radiology, Nuclear Medicine and Imaging. Their work covers core topics including:

  • Pancreatic and Hepatic Oncology Research
  • Cancer Genomics and Diagnostics
  • Peptidase Inhibition and Analysis
  • Protease and Inhibitor Mechanisms
  • Neuroendocrine Tumor Research Advances
  • Radiomics and Machine Learning in Medical Imaging
  • Cholangiocarcinoma and Gallbladder Cancer Studies

This profile outlines a research profile focused on advancing knowledge and clinical approaches in cancer biology, especially regarding pancreatic cancer treatment, molecular diagnostics, and imaging technologies.

Best Publications

  • Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

    Andrea Wang-Gillam;Chung-Pin Li;György Bodoky;Andrew Dean

  • EGF Receptor is Required for KRAS-induced Pancreatic Tumorigenesis

    Christine M. Ardito;Barbara M. Grüner;Kenneth K. Takeuchi;Clara Lubeseder-Martellato

  • Pancreatic Cancer: Basic and Clinical Aspects

    Günter Schneider;Jens T. Siveke;Florian Eckel;Roland M. Schmid

  • Cutting Edge: T Helper 1 and T Helper 2 Cells Respond Differentially to Chemokines

    Jens T. Siveke;Alf Hamann

  • Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

    Pawel K Mazur;Alexander Herner;Stephano S Mello;Matthias Wirth

  • NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors.

    Andrea Wang-Gillam;Richard A. Hubner;Jens T. Siveke;Daniel D. Von Hoff

  • Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

    Pawel K. Mazur;Henrik Einwächter;Marcel Lee;Bence Sipos

  • Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.

    Fabian Geisler;Florian Nagl;Pawel K. Mazur;Marcel Lee

  • [S3-guideline exocrine pancreatic cancer].

    T. Seufferlein;M. Porzner;T. Becker;V. Budach

  • Th1/Th2 subsets: distinct differences in homing and chemokine receptor expression?

    Uta Syrbe;Jens Siveke;Alf Hamann

  • Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

    Bastian Seubert;Barbara Grünwald;Julia Kobuch;Haissi Cui

  • RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells.

    P Duewell;A Steger;H Lohr;H Bourhis

  • Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

    Peter Horak;Christoph Heining;Simon Kreutzfeldt;Barbara Hutter

  • Notch Signaling Is Required for Exocrine Regeneration After Acute Pancreatitis

    Jens T Siveke;Clara Lubeseder-Martellato;Marcel Lee;Pawel K Mazur

  • The Latest Developments in Imaging of Fibroblast Activation Protein

    Annette Altmann;Annette Altmann;Uwe A. Haberkorn;Jens Siveke

  • Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN.

    Jens T. Siveke;Henrik Einwächter;Bence Sipos;Clara Lubeseder-Martellato

  • Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways

    Anna Melissa Schlitter;Diana Born;Marcus Bettstetter;Katja Specht

  • Lineage fate of ductular reactions in liver injury and carcinogenesis

    S Jörs;P Jeliazkova;M Ringelhan;J Thalhammer

  • Chemokine Receptor CCR1 But Not CCR5 Mediates Leukocyte Recruitment and Subsequent Renal Fibrosis after Unilateral Ureteral Obstruction

    Vaclav Eis;Bruno Luckow;Volker Vielhauer;Jens T. Siveke

  • Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues

    Michaela Aichler;Christopher Seiler;Monica Tost;Jens Siveke

Frequent Co-Authors

Roland M. Schmid
Roland M. Schmid Technical University of Munich
Irene Esposito
Irene Esposito Heinrich Heine University Düsseldorf
Volker Heinemann
Volker Heinemann Ludwig-Maximilians-Universität München
Bence Sipos
Bence Sipos University of Tübingen
David Cunningham
David Cunningham Royal Marsden NHS Foundation Trust
Daniel D. Von Hoff
Daniel D. Von Hoff Translational Genomics Research Institute
Ernst J. Rummeny
Ernst J. Rummeny Technical University of Munich
Wilko Weichert
Wilko Weichert Technical University of Munich
Axel Walch
Axel Walch Technical University of Munich
Mathias Heikenwalder
Mathias Heikenwalder German Cancer Research Center

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