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Medicine

D-Index
102
Citations
58011
World Ranking
7509
National Ranking
3920

Research.com Recognitions

  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Daniel D. Von Hoff is affiliated with the Translational Genomics Research Institute in the United States. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with a strong focus on oncology and molecular biology as notable subfields.

Their work covers a range of topics, including:

  • Pancreatic and Hepatic Oncology Research
  • Cancer Genomics and Diagnostics
  • Histone Deacetylase Inhibitors Research
  • Extracellular vesicles in disease
  • Cancer, Hypoxia, and Metabolism
  • MRI in cancer diagnosis
  • Radiomics and Machine Learning in Medical Imaging

Daniel D. Von Hoff has contributed to numerous scientific publications. Selected recent papers include:

  • BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial, 2020, Nature Medicine
  • Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions, 2020, Genome Medicine
  • Improvements in Survival and Clinical Benefit With Gemcitabine as First-Line Therapy for Patients With Advanced Pancreas Cancer: A Randomized Trial, 2023, Journal of Clinical Oncology
  • An Exosome-based Transcriptomic Signature for Noninvasive, Early Detection of Patients With Pancreatic Ductal Adenocarcinoma: A Multicenter Cohort Study, 2022, Gastroenterology
  • Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth, 2022, Med

Their frequent publication venues include:

  • Cancer Research
  • Journal of Clinical Oncology
  • The Oncologist
  • Frontiers in Oncology
  • Gastroenterology

Frequent co-authors of Daniel D. Von Hoff are:

  • Haiyong Han
  • Erkut Borazanci
  • Derek Cridebring
  • Gayle Jameson
  • Ajay Goel

Daniel D. Von Hoff was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 1992.

Best Publications

  • Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

    Daniel D. Von Hoff;Thomas Ervin;Francis P. Arena;E. Gabriela Chiorean

  • Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.

    Paolo P. Provenzano;Carlos Cuevas;Amy E. Chang;Vikas K. Goel

  • Hypersensitivity reactions from taxol.

    R B Weiss;R C Donehower;P H Wiernik;T Ohnuma

  • Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

    Daniel D. Von Hoff;Patricia M. LoRusso;Charles M. Rudin;Josina C. Reddy

  • Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies

    Manuel Hidalgo;Lillian L. Siu;John Nemunaitis;Jinee Rizzo

  • Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

    Jeffrey Hrkach;Daniel Von Hoff;Mir Mukkaram Ali;Elizaveta Andrianova

  • Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

    Andrea Wang-Gillam;Chung-Pin Li;György Bodoky;Andrew Dean

  • Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

    Charles M. Rudin;Christine L. Hann;John Laterra;Robert L. Yauch

  • Gemcitabine Plus nab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial

    Daniel D. Von Hoff;Ramesh K. Ramanathan;Mitesh J. Borad;Daniel A. Laheru

  • Tumor-stroma interactions in pancreatic ductal adenocarcinoma

    Daruka Mahadevan;Daniel D. Von Hoff

  • Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

    Daniel D. Von Hoff;Joseph J. Stephenson;Peter Rosen;David M. Loesch

  • nab-Paclitaxel Plus Gemcitabine for Metastatic Pancreatic Cancer: Long-Term Survival From a Phase III Trial

    David Goldstein;Robert Hassan El-Maraghi;Pascal Hammel;Volker Heinemann

  • Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development

    Eric K. Rowinsky;Jolene J. Windle;Daniel D. Von Hoff

  • American Society of Clinical Oncology 2008 Clinical Practice Guideline Update: Use of Chemotherapy and Radiation Therapy Protectants

    Martee L. Hensley;Karen L. Hagerty;Tarun Kewalramani;Daniel M. Green

  • Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis

    Denis Drygin;Adam Siddiqui-Jain;Sean O'Brien;Michael Schwaebe

  • Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.

    Patricia M. LoRusso;Charles M. Rudin;Josina C. Reddy;Raoul Tibes

  • Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

    Clifford J. Whatcott;Caroline H. Diep;Ping Jiang;Aprill Watanabe

  • A Phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer

    Ian Ganly;Ian Ganly;David Kirn;Susan G. Eckhardt;Gail I. Rodriguez

  • Daunomycin-induced cardiotoxicity in children and adults: A review of 110 cases

    Daniel D. Von Hoff;Marcel Rozencweig;Maxwell Layard;Milan Slavik

  • Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.

    William D Tap;Zev A Wainberg;Stephen P Anthony;Prabha N Ibrahim

Frequent Co-Authors

Gary M. Clark
Gary M. Clark The University of Texas Health Science Center at San Antonio
John D. Carpten
John D. Carpten University of Southern California
Manuel Hidalgo
Manuel Hidalgo Cornell University
David Goldstein
David Goldstein University of New South Wales
David Craig
David Craig University of Southern California
Josep Tabernero
Josep Tabernero Vall d´Hebron Institute of Oncology
Patricia LoRusso
Patricia LoRusso Yale University
Jeffrey R. Infante
Jeffrey R. Infante Janssen (Belgium)
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute

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