What is she best known for?
The fields of study she is best known for:
- Cell membrane
- Signal transduction
- T cell
Her primary scientific interests are in Cell biology, T cell, Immunological synapse, Signal transduction and Actin.
Janis K. Burkhardt interconnects Wiskott–Aldrich syndrome protein, Actin cytoskeleton, Jurkat cells and T-cell receptor in the investigation of issues within Cell biology.
Janis K. Burkhardt conducted interdisciplinary study in her works that combined T cell and CD43.
Her Immunological synapse research includes themes of ZAP70 and Antigen-presenting cell.
In her research, GTPase and Dynamin is intimately related to Internalization, which falls under the overarching field of Signal transduction.
Her work in Actin covers topics such as Tyrosine phosphorylation which are related to areas like Pleckstrin homology domain, Signal transducing adaptor protein and Cortactin.
Her most cited work include:
- Overexpression of the Dynamitin (p50) Subunit of the Dynactin Complex Disrupts Dynein-dependent Maintenance of Membrane Organelle Distribution (596 citations)
- Molecular ordering of the initial signaling events of CD95 (349 citations)
- The actin cytoskeleton in T cell activation. (268 citations)
What are the main themes of her work throughout her whole career to date?
Janis K. Burkhardt spends much of her time researching Cell biology, T cell, Immunological synapse, Actin and Cytoskeleton.
Her study in Cell biology focuses on Signal transduction in particular.
Janis K. Burkhardt studied T cell and CD8 that intersect with Major histocompatibility complex and Antigen presentation.
Her Immunological synapse research is multidisciplinary, incorporating perspectives in Cell signaling, Immunological Synapses, Cell adhesion molecule and ORAI1.
The Actin study combines topics in areas such as Tyrosine phosphorylation, T cell migration and Myosin.
Her Cytoskeleton research also works with subjects such as
- Cell polarity which intersects with area such as Uropod,
- Microtubule, which have a strong connection to Endocytic cycle and Nocodazole.
She most often published in these fields:
- Cell biology (102.24%)
- T cell (46.27%)
- Immunological synapse (35.07%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (102.24%)
- T cell (46.27%)
- Actin (37.31%)
In recent papers she was focusing on the following fields of study:
Cell biology, T cell, Actin, Integrin and Cytoskeleton are her primary areas of study.
Janis K. Burkhardt has included themes like Immunological synapse, T-cell receptor and Cytokine in her Cell biology study.
Her Immunological synapse research includes elements of Chimeric antigen receptor and Antigen.
Her T cell research is multidisciplinary, incorporating elements of Mechanotransduction, Priming and CD8.
Her biological study spans a wide range of topics, including T cell migration, Actin cytoskeleton and Motility.
Her studies deal with areas such as Signal transducing adaptor protein and Adapter molecule crk as well as Integrin.
Between 2017 and 2021, her most popular works were:
- Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse. (31 citations)
- Multiple actin networks coordinate mechanotransduction at the immunological synapse (17 citations)
- The Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse. (17 citations)
In her most recent research, the most cited papers focused on:
- Cell membrane
- Signal transduction
- Immune system
Janis K. Burkhardt mainly focuses on Cell biology, T cell, Integrin, Mechanotransduction and Actin cytoskeleton.
Janis K. Burkhardt is interested in Actin, which is a field of Cell biology.
She has researched T cell in several fields, including Immunodeficiency, Mechanistic target of rapamycin, Cytokine and Filamentous actin.
Her Mechanotransduction study combines topics from a wide range of disciplines, such as Cell and Priming.
The concepts of her T-cell receptor study are interwoven with issues in Vinculin, Paxillin and Focal adhesion.
Her work on Actin remodeling as part of general Cytoskeleton study is frequently connected to Ubiquitin ligase, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
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