Her primary scientific interests are in Cell biology, T cell, Immunological synapse, Signal transduction and Actin. Janis K. Burkhardt interconnects Wiskott–Aldrich syndrome protein, Actin cytoskeleton, Jurkat cells and T-cell receptor in the investigation of issues within Cell biology. Janis K. Burkhardt conducted interdisciplinary study in her works that combined T cell and CD43.
Her Immunological synapse research includes themes of ZAP70 and Antigen-presenting cell. In her research, GTPase and Dynamin is intimately related to Internalization, which falls under the overarching field of Signal transduction. Her work in Actin covers topics such as Tyrosine phosphorylation which are related to areas like Pleckstrin homology domain, Signal transducing adaptor protein and Cortactin.
Janis K. Burkhardt spends much of her time researching Cell biology, T cell, Immunological synapse, Actin and Cytoskeleton. Her study in Cell biology focuses on Signal transduction in particular. Janis K. Burkhardt studied T cell and CD8 that intersect with Major histocompatibility complex and Antigen presentation.
Her Immunological synapse research is multidisciplinary, incorporating perspectives in Cell signaling, Immunological Synapses, Cell adhesion molecule and ORAI1. The Actin study combines topics in areas such as Tyrosine phosphorylation, T cell migration and Myosin. Her Cytoskeleton research also works with subjects such as
Cell biology, T cell, Actin, Integrin and Cytoskeleton are her primary areas of study. Janis K. Burkhardt has included themes like Immunological synapse, T-cell receptor and Cytokine in her Cell biology study. Her Immunological synapse research includes elements of Chimeric antigen receptor and Antigen.
Her T cell research is multidisciplinary, incorporating elements of Mechanotransduction, Priming and CD8. Her biological study spans a wide range of topics, including T cell migration, Actin cytoskeleton and Motility. Her studies deal with areas such as Signal transducing adaptor protein and Adapter molecule crk as well as Integrin.
Janis K. Burkhardt mainly focuses on Cell biology, T cell, Integrin, Mechanotransduction and Actin cytoskeleton. Janis K. Burkhardt is interested in Actin, which is a field of Cell biology. She has researched T cell in several fields, including Immunodeficiency, Mechanistic target of rapamycin, Cytokine and Filamentous actin.
Her Mechanotransduction study combines topics from a wide range of disciplines, such as Cell and Priming. The concepts of her T-cell receptor study are interwoven with issues in Vinculin, Paxillin and Focal adhesion. Her work on Actin remodeling as part of general Cytoskeleton study is frequently connected to Ubiquitin ligase, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
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Overexpression of the Dynamitin (p50) Subunit of the Dynactin Complex Disrupts Dynein-dependent Maintenance of Membrane Organelle Distribution
Janis K. Burkhardt;Christophe J. Echeverri;Tommy Nilsson;Richard B. Vallee.
Journal of Cell Biology (1997)
Molecular ordering of the initial signaling events of CD95
Alicia Algeciras-Schimnich;Le Shen;Bryan C. Barnhart;Andrea E. Murmann.
Molecular and Cellular Biology (2002)
The actin cytoskeleton in T cell activation.
Janis K. Burkhardt;Esteban Carrizosa;Meredith H. Shaffer.
Annual Review of Immunology (2008)
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.
Eric J. Allenspach;Patrick Cullinan;Jiankun Tong;Qizhi Tang.
Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules
Ariel Blocker;Fedor F. Severin;Janis K. Burkhardt;James B. Bingham.
Journal of Cell Biology (1997)
The WAVE2 Complex Regulates Actin Cytoskeletal Reorganization and CRAC-Mediated Calcium Entry during T Cell Activation
Jeffrey C. Nolz;Timothy S. Gomez;Peimin Zhu;Shuixing Li.
Current Biology (2006)
Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinately.
David L. Wiest;Janis K. Burkhardt;Susan Hester;Michael Hortsch.
Journal of Cell Biology (1990)
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
Timothy S. Gomez;Sean D. McCarney;Esteban Carrizosa;Christine M. Labno.
Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions.
Yatin M. Vyas;Kamini M. Mehta;Margaret Morgan;Hina Maniar.
Journal of Immunology (2001)
Involvement of microtubule motors in basolateral and apical transport in kidney cells
Frank Lafont;Janis K. Burkhardt;Kai Simons.
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