Gillian M. Griffiths

Research.com Recognitions

• 2013 - Fellow of the Royal Society, United Kingdom

Overview

Best Publications

• The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges

  Jane C. Stinchcombe;Giovanna Bossi;Sarah Booth;Gillian M. Griffiths

  1182
  Citations

• Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton.

  Tadahiko Igakura;Jane C. Stinchcombe;Peter K. C. Goon;Graham P. Taylor

  880
  Citations

• Centrosome polarization delivers secretory granules to the immunological synapse

  Jane C. Stinchcombe;Endre Majorovits;Giovanna Bossi;Stephen Fuller

  835
  Citations

• Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

  Gillian M. Griffiths;Claudia Berek;Matti Kaartinen;Matti Kaartinen;Cesar Milstein

  737
  Citations

• Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

  Bossi G;Griffiths Gm

  549
  Citations

• Molecular events during maturation of the immune response to oxazolone.

  C. Berek;G. M. Griffiths;G. M. Griffiths;C. Milstein

  519
  Citations

• Linking Albinism and Immunity: The Secrets of Secretory Lysosomes

  Jane Stinchcombe;Giovanna Bossi;Gillian M. Griffiths

  494
  Citations

• Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.

  Udo zur Stadt;Jan Rohr;Wenke Seifert;Wenke Seifert;Florian Koch

  483
  Citations

• Rab27a is required for regulated secretion in cytotoxic T lymphocytes.

  Jane C. Stinchcombe;Duarte C. Barral;Emilie H. Mules;Sarah Booth

  461
  Citations

• Secretory mechanisms in cell-mediated cytotoxicity.

  Jane C. Stinchcombe;Gillian M. Griffiths

  414
  Citations

• mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification.

  Matti Kaartinen;Matti Kaartinen;Gillian M. Griffiths;Alex F. Markham;Cesar Milstein

  397
  Citations

• Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.

  S Rabinowitz;H Horstmann;S Gordon;G Griffiths

  393
  Citations

• The Biogenesis of Lysosomes and Lysosome-Related Organelles

  J. Paul Luzio;Yvonne Hackmann;Nele M.G. Dieckmann;Gillian M. Griffiths

  368
  Citations

• Adaptor protein 3–dependent microtubule-mediated movement of lytic granules to the immunological synapse

  Richard H Clark;Jane C Stinchcombe;Anna Day;Emma Blott

  335
  Citations

• Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines

  Ji-Li Chen;Guillaume Stewart-Jones;Giovanna Bossi;Nikolai M. Lissin

  330
  Citations

• Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse

  Alex T. Ritter;Yukako Asano;Jane C. Stinchcombe;N.M.G. Dieckmann

  325
  Citations

• Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.

  Sylvie Isaaz;Kristin Baetz;Kristin Olsen;Eckhard Podack

  313
  Citations

• Delivering the kiss of death

  Christina M Trambas;Gillian M Griffiths

  279
  Citations

• The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

  C McCarthy;D Shepherd;S Fleire;V S Stronge

  262
  Citations

• The immunological synapse: a focal point for endocytosis and exocytosis

  Gillian M. Griffiths;Andy Tsun;Jane C. Stinchcombe

  255
  Citations