2013 - Fellow of the Royal Society, United Kingdom
Gillian M. Griffiths mostly deals with Cell biology, Immunological synapse, Cytotoxic T cell, Immune system and Immunology. Her Cell biology research incorporates themes from Natural killer T cell, Secretion, Exocytosis and Perforin, Granzyme. Her biological study spans a wide range of topics, including CTL*, Cell type and Cytoskeleton.
Her Granzyme research is multidisciplinary, incorporating perspectives in Lytic cycle and Granzyme A. As a part of the same scientific study, Gillian M. Griffiths usually deals with the Immunological synapse, concentrating on Immunological Synapses and frequently concerns with Microtubule, IQGAP1, Cell polarity and Cell membrane. Her Immune system research is multidisciplinary, relying on both Oxazolone and Antibody, Hapten.
The scientist’s investigation covers issues in Cell biology, Cytotoxic T cell, Immunological synapse, Immunology and CTL*. Her Cell biology study incorporates themes from Lysosome, Secretion, T cell, Immune system and Immunological Synapses. Her Cytotoxic T cell study combines topics from a wide range of disciplines, such as Fas ligand, Virology, Degranulation and Cytotoxicity.
Her work carried out in the field of Immunological synapse brings together such families of science as Cell membrane, Cytoskeleton, Actin, Synapse and Cell polarity. Her research in Immunology intersects with topics in Hemophagocytic lymphohistiocytosis and Mutation. As part of the same scientific family, she usually focuses on CTL*, concentrating on Molecular biology and intersecting with Gene, Oxazolone, Epitope and Messenger RNA.
Gillian M. Griffiths mainly focuses on Cell biology, Immunological synapse, Immunology, Cytotoxic T cell and CTL*. Her Cell biology research includes themes of T cell, Immunological Synapses, T-cell receptor, CD8 and Degranulation. The concepts of her Immunological synapse study are interwoven with issues in Secretion, Cell membrane, Cilium, Actin and Synapse.
Her Secretion research integrates issues from Cell and Organelle. She combines subjects such as Hemophagocytic lymphohistiocytosis and Virology with her study of Immunology. Her CTL* research focuses on STX11 and how it connects with Cytolytic granule, Syntaxin binding, Molecular biology, Point mutation and Binding site.
Her primary areas of study are Cell biology, Immunological synapse, Cytotoxic T cell, Immunological Synapses and Actin. Her work deals with themes such as ATG16L1 and Organelle biogenesis, which intersect with Cell biology. Her study in Immunological synapse is interdisciplinary in nature, drawing from both Secretion, Microtubule, CTL* and Ciliogenesis.
Her Cytotoxic T cell research is multidisciplinary, incorporating elements of T cell immunology, Immune system, Antigen and Cancer immunotherapy. Gillian M. Griffiths works mostly in the field of Immune system, limiting it down to topics relating to Bioinformatics and, in certain cases, Familial Hemophagocytic Lymphohistiocytosis, Disease and Immunology. Her Immunological Synapses study integrates concerns from other disciplines, such as Cell membrane, Actin remodeling and Hedgehog signaling pathway.
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The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges
Jane C. Stinchcombe;Giovanna Bossi;Sarah Booth;Gillian M. Griffiths.
Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton.
Tadahiko Igakura;Jane C. Stinchcombe;Peter K. C. Goon;Graham P. Taylor.
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone
Gillian M. Griffiths;Claudia Berek;Matti Kaartinen;Matti Kaartinen;Cesar Milstein.
Centrosome polarization delivers secretory granules to the immunological synapse
Jane C Stinchcombe;Endre Majorovits;Giovanna Bossi;Stephen Fuller.
Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells
Bossi G;Griffiths Gm.
Nature Medicine (1999)
Molecular events during maturation of the immune response to oxazolone.
C. Berek;G. M. Griffiths;G. M. Griffiths;C. Milstein.
Linking Albinism and Immunity: The Secrets of Secretory Lysosomes
Jane Stinchcombe;Giovanna Bossi;Gillian M. Griffiths.
Rab27a is required for regulated secretion in cytotoxic T lymphocytes.
Jane C. Stinchcombe;Duarte C. Barral;Emilie H. Mules;Sarah Booth.
Journal of Cell Biology (2001)
Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.
Udo zur Stadt;Jan Rohr;Wenke Seifert;Wenke Seifert;Florian Koch.
American Journal of Human Genetics (2009)
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification.
Matti Kaartinen;Matti Kaartinen;Gillian M. Griffiths;Alex F. Markham;Cesar Milstein.
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