D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 18,284 128 World Ranking 4038 National Ranking 320

Research.com Recognitions

Awards & Achievements

2013 - Fellow of the Royal Society, United Kingdom

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Enzyme

Gillian M. Griffiths mostly deals with Cell biology, Immunological synapse, Cytotoxic T cell, Immune system and Immunology. Her Cell biology research incorporates themes from Natural killer T cell, Secretion, Exocytosis and Perforin, Granzyme. Her biological study spans a wide range of topics, including CTL*, Cell type and Cytoskeleton.

Her Granzyme research is multidisciplinary, incorporating perspectives in Lytic cycle and Granzyme A. As a part of the same scientific study, Gillian M. Griffiths usually deals with the Immunological synapse, concentrating on Immunological Synapses and frequently concerns with Microtubule, IQGAP1, Cell polarity and Cell membrane. Her Immune system research is multidisciplinary, relying on both Oxazolone and Antibody, Hapten.

Her most cited work include:

  • The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges (689 citations)
  • Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton. (576 citations)
  • Centrosome polarization delivers secretory granules to the immunological synapse (469 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Cell biology, Cytotoxic T cell, Immunological synapse, Immunology and CTL*. Her Cell biology study incorporates themes from Lysosome, Secretion, T cell, Immune system and Immunological Synapses. Her Cytotoxic T cell study combines topics from a wide range of disciplines, such as Fas ligand, Virology, Degranulation and Cytotoxicity.

Her work carried out in the field of Immunological synapse brings together such families of science as Cell membrane, Cytoskeleton, Actin, Synapse and Cell polarity. Her research in Immunology intersects with topics in Hemophagocytic lymphohistiocytosis and Mutation. As part of the same scientific family, she usually focuses on CTL*, concentrating on Molecular biology and intersecting with Gene, Oxazolone, Epitope and Messenger RNA.

She most often published in these fields:

  • Cell biology (61.54%)
  • Cytotoxic T cell (34.27%)
  • Immunological synapse (30.07%)

What were the highlights of her more recent work (between 2012-2021)?

  • Cell biology (61.54%)
  • Immunological synapse (30.07%)
  • Immunology (27.27%)

In recent papers she was focusing on the following fields of study:

Gillian M. Griffiths mainly focuses on Cell biology, Immunological synapse, Immunology, Cytotoxic T cell and CTL*. Her Cell biology research includes themes of T cell, Immunological Synapses, T-cell receptor, CD8 and Degranulation. The concepts of her Immunological synapse study are interwoven with issues in Secretion, Cell membrane, Cilium, Actin and Synapse.

Her Secretion research integrates issues from Cell and Organelle. She combines subjects such as Hemophagocytic lymphohistiocytosis and Virology with her study of Immunology. Her CTL* research focuses on STX11 and how it connects with Cytolytic granule, Syntaxin binding, Molecular biology, Point mutation and Binding site.

Between 2012 and 2021, her most popular works were:

  • Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse (165 citations)
  • The Biogenesis of Lysosomes and Lysosome-Related Organelles (162 citations)
  • Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome. (87 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Enzyme

Her primary areas of study are Cell biology, Immunological synapse, Cytotoxic T cell, Immunological Synapses and Actin. Her work deals with themes such as ATG16L1 and Organelle biogenesis, which intersect with Cell biology. Her study in Immunological synapse is interdisciplinary in nature, drawing from both Secretion, Microtubule, CTL* and Ciliogenesis.

Her Cytotoxic T cell research is multidisciplinary, incorporating elements of T cell immunology, Immune system, Antigen and Cancer immunotherapy. Gillian M. Griffiths works mostly in the field of Immune system, limiting it down to topics relating to Bioinformatics and, in certain cases, Familial Hemophagocytic Lymphohistiocytosis, Disease and Immunology. Her Immunological Synapses study integrates concerns from other disciplines, such as Cell membrane, Actin remodeling and Hedgehog signaling pathway.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges

Jane C. Stinchcombe;Giovanna Bossi;Sarah Booth;Gillian M. Griffiths.
Immunity (2001)

1076 Citations

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton.

Tadahiko Igakura;Jane C. Stinchcombe;Peter K. C. Goon;Graham P. Taylor.
Science (2003)

740 Citations

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

Gillian M. Griffiths;Claudia Berek;Matti Kaartinen;Matti Kaartinen;Cesar Milstein.
Nature (1984)

722 Citations

Centrosome polarization delivers secretory granules to the immunological synapse

Jane C Stinchcombe;Endre Majorovits;Giovanna Bossi;Stephen Fuller.
Nature (2006)

720 Citations

Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

Bossi G;Griffiths Gm.
Nature Medicine (1999)

520 Citations

Molecular events during maturation of the immune response to oxazolone.

C. Berek;G. M. Griffiths;G. M. Griffiths;C. Milstein.
Nature (1985)

509 Citations

Linking Albinism and Immunity: The Secrets of Secretory Lysosomes

Jane Stinchcombe;Giovanna Bossi;Gillian M. Griffiths.
Science (2004)

462 Citations

Rab27a is required for regulated secretion in cytotoxic T lymphocytes.

Jane C. Stinchcombe;Duarte C. Barral;Emilie H. Mules;Sarah Booth.
Journal of Cell Biology (2001)

429 Citations

Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.

Udo zur Stadt;Jan Rohr;Wenke Seifert;Wenke Seifert;Florian Koch.
American Journal of Human Genetics (2009)

390 Citations

mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification.

Matti Kaartinen;Matti Kaartinen;Gillian M. Griffiths;Alex F. Markham;Cesar Milstein.
Nature (1983)

389 Citations

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