Cesar Milstein

Research.com Recognitions

• 1984 - Nobel Prize for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies
• 1981 - Member of the National Academy of Sciences
• 1980 - Robert Koch Prize

Overview

Best Publications

• Antibodies to major histocompatibility antigens produced by hybrid cell lines.

  Galfre G;Galfre G;Howe Sc;Milstein C;Butcher Gw

  2731
  Citations

• Man-made antibodies

  Greg Winter;César Milstein

  1689
  Citations

• Mac‐1: a macrophage differentiation antigen identified by monoclonal antibody

  Timothy Springer;Giovanni Galfré;David S. Secher;Cesar Milstein

  1381
  Citations

• Reshaping human antibodies: grafting an antilysozyme activity

  Martine Verhoeyen;Cesar Milstein;Greg Winter

  1376
  Citations

• Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

  C M Wischik;M Novak;H C Thøgersen;P C Edwards

  1209
  Citations

• Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes.

  Alan F. Williams;Giovanni Galfrè;Cesar Milstein

  1037
  Citations

• Hybrid hybridomas and their use in immunohistochemistry

  C. Milstein;A. C. Cuello

  894
  Citations

• Mutation drift and repertoire shift in the maturation of the immune response.

  Claudia Berek;Cesar Milstein

  878
  Citations

• Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens

  T. Springer;G. Galfrè;D. S. Secher;C. Milstein

  815
  Citations

• Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

  Gillian M. Griffiths;Claudia Berek;Matti Kaartinen;Matti Kaartinen;Cesar Milstein

  737
  Citations

• Detection of substance P in the central nervous system by a monoclonal antibody

  A C Cuello;G Galfre;C Milstein

  665
  Citations

• Molecular events during maturation of the immune response to oxazolone.

  C. Berek;G. M. Griffiths;G. M. Griffiths;C. Milstein

  519
  Citations

• Elements regulating somatic hypermutation of an immunoglobulin κ gene : critical role for the intron enhancer/matrix attachment region

  Alexander G. Betz;César Milstein;Africa González-Fernández;Richard Pannell

  494
  Citations

• Continuous cultures of fused cells secreting antibody of predefined specificity. 1975.

  G Köhler;C Milstein

  464
  Citations

• The Dynamic Nature of the Antibody Repertoire

  Claudia Berek;Cesar Milstein

  450
  Citations

• Origin of antibody variation.

  S. Brenner;C. Milstein

  412
  Citations

• Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting.

  Cristina Rada;Michael R. Ehrenstein;Michael S. Neuberger;César Milstein

  411
  Citations

• Kinetic maturation of an immune response

  Jefferson Foote;César Milstein

  408
  Citations

• mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification.

  Matti Kaartinen;Matti Kaartinen;Gillian M. Griffiths;Alex F. Markham;Cesar Milstein

  397
  Citations

• Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots.

  Alexander G. Betz;Cristina Rada;Richard Pannell;Cesar Milstein

  380
  Citations