What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Molecular biology, Somatic hypermutation, Antibody, Antigen and Genetics.
Michael S. Neuberger interconnects Enhancer and Transfection in the investigation of issues within Molecular biology.
His research investigates the connection between Somatic hypermutation and topics such as MSH2 that intersect with problems in Mutation Accumulation, Mutation Fixation, Germinal center and MSH6.
His work focuses on many connections between Antibody and other disciplines, such as Receptor, that overlap with his field of interest in Isotype, Glycosylation and Autoantibody.
Michael S. Neuberger has researched Antigen in several fields, including Immunoglobulin E and B-cell receptor.
The concepts of his Immunoglobulin light chain study are interwoven with issues in Monoclonal antibody, Peptide sequence, Myeloma protein and Hypervariable region.
His most cited work include:
- Replacing the complementarity-determining regions in a human antibody with those from a mouse (2468 citations)
- DNA deamination mediates innate immunity to (retro)viral infection (1204 citations)
- AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification (796 citations)
What are the main themes of his work throughout his whole career to date?
Molecular biology, Somatic hypermutation, Antibody, Genetics and Gene are his primary areas of study.
Michael S. Neuberger combines subjects such as Immunoglobulin gene, Transgene, B cell, Antigen and Immunoglobulin light chain with his study of Molecular biology.
The various areas that Michael S. Neuberger examines in his Antigen study include B-cell receptor, B-1 cell and Cell biology.
His Somatic hypermutation study also includes fields such as
- Mutation together with Nucleotide,
- DNA glycosylase which connect with Deamination.
His work investigates the relationship between Antibody and topics such as Genetically modified mouse that intersect with problems in Germline.
His studies in Cytidine deaminase integrate themes in fields like Activation-induced deaminase and Virology.
He most often published in these fields:
- Molecular biology (51.05%)
- Somatic hypermutation (38.46%)
- Antibody (35.66%)
What were the highlights of his more recent work (between 2003-2017)?
- Somatic hypermutation (38.46%)
- Genetics (32.87%)
- Molecular biology (51.05%)
In recent papers he was focusing on the following fields of study:
His main research concerns Somatic hypermutation, Genetics, Molecular biology, Immunoglobulin class switching and Cytidine deaminase.
DNA deamination is the focus of his Somatic hypermutation research.
His Molecular biology research incorporates themes from DNA glycosylase, Immunoglobulin heavy chain, Immunoglobulin G, Deamination and B cell.
His study with Immunoglobulin G involves better knowledge in Antibody.
His Cytidine deaminase study combines topics in areas such as Cytidine, Activation-induced deaminase and Protein degradation.
His Endogeny research includes themes of Epitope, Affinity maturation, Antigen, Immunoglobulin M and Monoclonal antibody.
Between 2003 and 2017, his most popular works were:
- Evolution of the AID/APOBEC Family of Polynucleotide (Deoxy)cytidine Deaminases (418 citations)
- Mismatch Recognition and Uracil Excision Provide Complementary Paths to Both Ig Switching and the A/T-Focused Phase of Somatic Mutation (404 citations)
- DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. (250 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Somatic hypermutation, Genetics, APOBEC Deaminases, Molecular biology and Immunoglobulin class switching.
His Somatic hypermutation research integrates issues from Mutation and DNA glycosylase.
His study of Cytidine deaminase is a part of Genetics.
His APOBEC Deaminases study incorporates themes from APOBEC3A, Cytidine deamination and APOBEC1.
As part of his studies on Molecular biology, Michael S. Neuberger often connects relevant areas like Deamination.
His Immunoglobulin class switching study integrates concerns from other disciplines, such as Uracil-DNA glycosylase and Antibody Diversity.
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