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Inger Sandlie

Inger Sandlie

D-Index & Metrics

Microbiology

D-Index
59
Citations
10270
World Ranking
3319
National Ranking
13

Overview

Inger Sandlie is affiliated with the University of Oslo in Norway and has an extensive publication record in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research covers several subfields, including Radiology, Nuclear Medicine and Imaging, Molecular Biology, Hematology, Immunology, and Cell Biology.

The scientist's work focuses on topics such as Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research, Blood groups and transfusion, T-cell and B-cell Immunology, Platelet Disorders and Treatments, Hemoglobin structure and function, and Protein purification and stability.

Recent papers authored or co-authored by Inger Sandlie include:

  • An intact C-terminal end of albumin is required for its long half-life in humans (2020, Communications Biology)
  • An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics (2020, Science Translational Medicine)
  • Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo (2021, mAbs)
  • Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life (2022, iScience)
  • FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity (2020, The Journal of Experimental Medicine)

Their most frequent publication venues consist of:

  • Communications Biology
  • Nature Communications
  • Science Immunology
  • PNAS Nexus
  • Science Translational Medicine

Inger Sandlie has collaborated frequently with various co-authors, including:

  • Jan Terje Andersen
  • Jeannette Nilsen
  • Stian Foss
  • Simone Mester
  • Algirdas Grevys

Best Publications

  • Therapeutic antibodies for human diseases at the dawn of the twenty-first century

    Ole Henrik Brekke;Inger Sandlie

  • The Neonatal Fc Receptor (FcRn): A Misnomer?

    Michal Pyzik;Kine Marita Knudsen Sand;Kine Marita Knudsen Sand;Jonathan J. Hubbard;Jonathan J. Hubbard;Jan Terje Andersen

  • Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

    Kine Marita Knudsen Sand;Kine Marita Knudsen Sand;Malin C. Bern;Malin C. Bern;Jeannette Nilsen;Jeannette Nilsen;Hanna Theodora Noordzij;Hanna Theodora Noordzij

  • Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

    Nigel M. Stapleton;Jan Terje Andersen;Jan Terje Andersen;Annette M. Stemerding;Stefania P. Bjarnarson

  • Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.

    Kristi Baker;Shuo-Wang Qiao;Timothy T. Kuo;Victoria G. Aveson

  • Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells

    Lars Norderhaug;Tove Olafsen;Terje E Michaelsen;Inger Sandlie

  • Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding

    Jan Terje Andersen;Muluneh Bekele Daba;Gøril Berntzen;Terje Einar Michaelsen;Terje Einar Michaelsen

  • Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.

    Jan Terje Andersen;Bjørn Dalhus;Jason Cameron;Muluneh Bekele Daba;Muluneh Bekele Daba

  • The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery

    Malin Bern;Kine Marita Knudsen Sand;Kine Marita Knudsen Sand;Jeannette Nilsen;Inger Sandlie;Inger Sandlie

  • The structural requirements for complement activation by IgG: does it hinge on the hinge?

    Ole Henrik Brekke;Terje E. Michaelsen;Inger Sandlie

  • Binding to Nanopatterned Antigens is Dominated by the Spatial Tolerance of Antibodies

    Alan Shaw;Ian T. Hoffecker;Ioanna Smyrlaki;Joao Rosa

  • Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding

    Jan Terje Andersen;Bjørn Dalhus;Dorthe Viuff;Birgitte Thue Ravn

  • Aglycosylated IgG variants expressed in bacteria that selectively bind FcγRI potentiate tumor cell killing by monocyte-dendritic cells

    Sang Taek Jung;Sai T. Reddy;Tae Hyun Kang;M. Jack Borrok

  • Lysine 322 in the human IgG3 C(H)2 domain is crucial for antibody dependent complement activation.

    John E Thommesen;Terje E Michaelsen;Geir Åge Løset;Inger Sandlie

  • Comparisons of the Ability of Human IgG3 Hinge Mutants, IgM, IgE, and IgA2, to Form Small Immune Complexes: A Role for Flexibility and Geometry

    Kenneth H. Roux;Lioudmila Strelets;Ole Henrik Brekke;Inger Sandlie

  • The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin.

    Jan Terje Andersen;Julie Dee Qian;Inger Sandlie

  • The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

    Jan Terje Andersen;Inger Sandlie

  • TRIM21-From Intracellular Immunity to Therapy

    Stian Foss;Maria Bottermann;Alexandra Jonsson;Inger Sandlie;Inger Sandlie

  • Enhancement of Complement Activation and Cytolysis of Human IgG3 by Deletion of Hinge Exons

    T E Michaelsen;A Aase;C Westby;I Sandlie

  • The influence of the hinge region length in binding of human IgG to human Fcγ receptors

    Stella Redpath;Stella Redpath;Terje E. Michaelsen;Inger Sandlie;Michael R. Clark

  • Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells

    Gøril Berntzen;Elin Lunde;Morten Flobakk;Jan Terje Andersen

Frequent Co-Authors

Jan Terje Andersen
Jan Terje Andersen University of Oslo
Terje E. Michaelsen
Terje E. Michaelsen University of Oslo
Bjarne Bogen
Bjarne Bogen Oslo University Hospital
Ludvig M. Sollid
Ludvig M. Sollid Oslo University Hospital
Derry C. Roopenian
Derry C. Roopenian The Jackson Laboratory
Richard S. Blumberg
Richard S. Blumberg Brigham and Women's Hospital
Finn-Eirik Johansen
Finn-Eirik Johansen University of Oslo
Leo C. James
Leo C. James MRC Laboratory of Molecular Biology
Knut E.A. Lundin
Knut E.A. Lundin University of Oslo
Melvyn Little
Melvyn Little German Cancer Research Center

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