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Immunology

D-Index
64
Citations
17281
World Ranking
2912
National Ranking
263

Overview

E. Sally Ward is affiliated with the University of Southampton in the United Kingdom. Their research is primarily focused on Medicine and Immunology and Microbiology, with publication activity spanning 24 works in Medicine and 9 in Immunology and Microbiology.

Their work covers several subfields including Radiology, Nuclear Medicine and Imaging, Immunology, Oncology, Pathology and Forensic Medicine, and Rheumatology. Key research topics addressed in their publications include Monoclonal and Polyclonal Antibodies Research, Autoimmune Bullous Skin Diseases, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, HER2/EGFR in Cancer Research, CAR-T cell therapy research, and Coagulation, Bradykinin, Polyphosphates, and Angioedema.

Frequent publication venues for this scientist include:

  • mAbs
  • British Journal of Dermatology
  • Frontiers in Immunology
  • JCI Insight
  • Journal of the Neurological Sciences

Frequent co-authors in their research include:

  • Hans de Haard
  • Raimund J. Ober
  • Matthias Goebeler
  • Zsuzsanna Bata-Csörgõ
  • Clara De Simone

Selected recent papers authored or co-authored by E. Sally Ward are:

  • Treatment of pemphigus vulgaris and foliaceus with efgartigimod, a neonatal Fc receptor inhibitor: a phase II multicentre, open-label feasibility trial, 2021, British Journal of Dermatology
  • Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders, 2022, Frontiers in Immunology
  • IgG regulation through FcRn blocking: A novel mechanism for the treatment of myasthenia gravis, 2021, Journal of the Neurological Sciences
  • Selective Depletion of Antigen-Specific Antibodies for the Treatment of Demyelinating Disease, 2020, Molecular Therapy
  • Differential effects of FcRn antagonists on the subcellular trafficking of FcRn and albumin, 2024, JCI Insight

Best Publications

  • Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

    E. Sally Ward;Detlef Güssow;Andrew D. Griffiths;Peter T. Jones

  • Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies.

    Raimund J. Ober;Caius G. Radu;Victor Ghetie;E. Sally Ward

  • Abnormally short serum half‐lives of IgG in β2‐microglobulin‐deficient mice

    Victor Ghetie;James G. Hubbard;Jin Kyoo Kim;May Fang Tsen

  • Increasing the Affinity of a Human IgG1 for the Neonatal Fc Receptor: Biological Consequences

    William F. Dall’ Acqua;Robert M. Woods;E. Sally Ward;Susan R. Palaszynski

  • Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

    Carlos Vaccaro;Jinchun Zhou;Raimund J Ober;Raimund J Ober;E Sally Ward

  • Receptor-mediated Immunoglobulin G Transport Across Mucosal Barriers in Adult Life: Functional Expression of FcRn in the Mammalian Lung

    Gerburg M. Spiekermann;Patricia W. Finn;Patricia W. Finn;E. Sally Ward;Jennifer Dumont

  • Increasing the serum persistence of an IgG fragment by random mutagenesis.

    Victor Ghetie;Serguei Popov;Jozef Borvak;Caius Radu

  • Visualizing the Site and Dynamics of IgG Salvage by the MHC Class I-Related Receptor, FcRn

    Raimund J. Ober;Cruz Martinez;Carlos Vaccaro;Jinchun Zhou

  • The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of γ-globulin in humans

    Mihail Firan;Roger Bawdon;Caius Radu;Raimund J. Ober

  • Exocytosis of IgG as mediated by the receptor, FcRn: An analysis at the single-molecule level

    Raimund J. Ober;Cruz Martinez;Xuming Lai;Jinchun Zhou

  • FcRn: the MHC class I-related receptor that is more than an IgG transporter.

    Victor Ghetie;E.Sally Ward

  • Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans

    Peter Ulrichts;Antonio Guglietta;Torsten Dreier;Tonke van Bragt

  • High Accuracy 3D Quantum Dot Tracking with Multifocal Plane Microscopy for the Study of Fast Intracellular Dynamics in Live Cells

    Sripad Ram;Prashant Prabhat;Prashant Prabhat;Jerry Chao;Jerry Chao;E. Sally Ward

  • Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor

    Jin‐Kyoo ‐K Kim;May‐Fang ‐F Tsen;Victor Ghetie;E. Sally Ward

  • Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

    Jin-Kyoo Kim;Mihail Firan;Caius G. Radu;Cheol-Hong Kim

  • Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

    Junke Zheng;Junke Zheng;Masato Umikawa;Masato Umikawa;Changhao Cui;Jiyuan Li

  • Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice.

    J Borvak;J Richardson;C Medesan;C Medesan;F Antohe

  • Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

    E. Sally Ward;Jinchun Zhou;Victor Ghetie;Raimund J. Ober

  • Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site‐directed mutagenesis

    Jin‐Kyoo Kim;May‐Fang Tsen;Victor Ghetie;E. Sally Ward

  • Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

    Héctor Pérez Montoyo;Carlos Vaccaro;Martin Hafner;Raimund J. Ober

  • Crystal Structure of the Vα Domain of a T Cell Antigen Receptor

    Barry A. Fields;Bertram Ober;Emilio L. Malchiodi;Marina I. Lebedeva

Frequent Co-Authors

Victor Ghetie
Victor Ghetie The University of Texas Southwestern Medical Center
Caius G. Radu
Caius G. Radu University of California, Los Angeles
Zhiping Lin
Zhiping Lin Nanyang Technological University
Eli E. Sercarz
Eli E. Sercarz Torrey Pines Institute For Molecular Studies
Michael K. Racke
Michael K. Racke Quest Diagnostics (United States)
Elliot M. Frohman
Elliot M. Frohman The University of Texas at Austin
Roberto J. Poljak
Roberto J. Poljak University of Maryland, College Park
K. Christopher Garcia
K. Christopher Garcia Stanford University
Herren Wu
Herren Wu AstraZeneca (United Kingdom)
Cheng Cheng Zhang
Cheng Cheng Zhang The University of Texas Southwestern Medical Center

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