D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 68 Citations 17,860 217 World Ranking 1697 National Ranking 840

Research.com Recognitions

Awards & Achievements

2013 - AAI Distinguished Service Award, American Association of Immunologists For outstanding service to AAI and the immunology community as member and Chair of the AAI Committee on Public Affairs, 2005-2012

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antibody

His primary areas of investigation include Immunology, Neonatal Fc receptor, Immunoglobulin G, MHC class I and Molecular biology. His work investigates the relationship between Immunology and topics such as Cytotoxic T cell that intersect with problems in T cell and NOD mice. His studies deal with areas such as Receptor and In vivo as well as Neonatal Fc receptor.

As part of the same scientific family, he usually focuses on Immunoglobulin G, concentrating on Fc receptor and intersecting with Pemphigus, Pemphigoid, Pemphigus foliaceus, Bullous pemphigoid and Pemphigus vulgaris. His MHC class I research is multidisciplinary, incorporating elements of Transcytosis, Autoimmune disease and Proinflammatory cytokine. His Molecular biology research includes elements of B-cell receptor, B cell, Allele and Resorption.

His most cited work include:

  • FcRn: the neonatal Fc receptor comes of age (1548 citations)
  • Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6 (586 citations)
  • Enhanced antibody half-life improves in vivo activity (460 citations)

What are the main themes of his work throughout his whole career to date?

Derry C. Roopenian focuses on Immunology, Antigen, Molecular biology, Major histocompatibility complex and CD8. The study of Immunology is intertwined with the study of Porphyromonas gingivalis in a number of ways. His Antigen research is multidisciplinary, relying on both Cytotoxic T cell and Antigen presentation.

His research integrates issues of In vitro, Lymphokine, Peptide sequence, Gene and CTL* in his study of Molecular biology. His specific area of interest is Immunoglobulin G, where Derry C. Roopenian studies Neonatal Fc receptor. His research investigates the connection between Neonatal Fc receptor and topics such as Receptor that intersect with issues in Albumin.

He most often published in these fields:

  • Immunology (51.65%)
  • Antigen (24.79%)
  • Molecular biology (24.79%)

What were the highlights of his more recent work (between 2012-2020)?

  • Immunology (51.65%)
  • Neonatal Fc receptor (11.98%)
  • Cell biology (9.09%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immunology, Neonatal Fc receptor, Cell biology, Antibody and Immunoglobulin G. His research ties Cytotoxic T cell and Immunology together. His Neonatal Fc receptor study integrates concerns from other disciplines, such as Retina, Albumin, Pharmacology, Transcytosis and Monoclonal antibody.

Derry C. Roopenian has included themes like Plasma cell, Recombinant antibodies, Antigen and Pathology in his Cell biology study. His Antibody research is multidisciplinary, incorporating perspectives in Carbohydrate metabolism and Major histocompatibility complex. Derry C. Roopenian works mostly in the field of Major histocompatibility complex, limiting it down to topics relating to Human leukocyte antigen and, in certain cases, Antigen presentation and Molecular biology.

Between 2012 and 2020, his most popular works were:

  • The Immunologic Functions of the Neonatal Fc Receptor for IgG (104 citations)
  • Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury (49 citations)
  • Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies (49 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

Derry C. Roopenian spends much of his time researching Immunology, Immunoglobulin G, Neonatal Fc receptor, Antibody and Monoclonal antibody. As part of his studies on Immunology, Derry C. Roopenian often connects relevant areas like Systemic lupus erythematosus. His Immunoglobulin G research incorporates elements of Germinal center, Spleen, Microarray, Angioimmunoblastic T-cell lymphoma and Cell biology.

His Antibody research integrates issues from Major histocompatibility complex, Immune system and Immunity. His research investigates the connection between Monoclonal antibody and topics such as Receptor that intersect with problems in Albumin. Derry C. Roopenian interconnects MHC class I, Antigen, MHC class II and Antigen-presenting cell in the investigation of issues within Antigen presentation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

FcRn: the neonatal Fc receptor comes of age

Derry C. Roopenian;Shreeram Akilesh.
Nature Reviews Immunology (2007)

2179 Citations

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

Katsutoshi Ozaki;Katsutoshi Ozaki;Rosanne Spolski;Rachel Ettinger;Hyoung Fyo Kim.
Journal of Immunology (2004)

782 Citations

The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan.

Chaity Chaudhury;Samina Mehnaz;John M. Robinson;William L. Hayton.
Journal of Experimental Medicine (2003)

606 Citations

Enhanced antibody half-life improves in vivo activity

Jonathan Zalevsky;Aaron K Chamberlain;Holly M Horton;Sher Karki.
Nature Biotechnology (2010)

580 Citations

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease

Stefka B. Petkova;Shreeram Akilesh;Thomas J. Sproule;Gregory J. Christianson.
International Immunology (2006)

480 Citations

Human Neonatal Fc Receptor Mediates Transport of IgG into Luminal Secretions for Delivery of Antigens to Mucosal Dendritic Cells

Masaru Yoshida;Steven M Claypool;Jessica S Wagner;Emiko Mizoguchi.
Immunity (2004)

479 Citations

The MHC Class I-Like IgG Receptor Controls Perinatal IgG Transport, IgG Homeostasis, and Fate of IgG-Fc-Coupled Drugs

Derry C. Roopenian;Gregory J. Christianson;Thomas J. Sproule;Aaron C. Brown.
Journal of Immunology (2003)

472 Citations

CD4+ T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice

P J Baker;M Dixon;R T Evans;L Dufour.
Infection and Immunity (1999)

403 Citations

Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant

David V Serreze;Edward H Leiter;Gregory J Christianson;Dale Greiner.
Diabetes (1994)

389 Citations

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice.

Jason A. Bubier;Thomas J. Sproule;Oded Foreman;Rosanne Spolski.
Proceedings of the National Academy of Sciences of the United States of America (2009)

330 Citations

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