2013 - AAI Distinguished Service Award, American Association of Immunologists For outstanding service to AAI and the immunology community as member and Chair of the AAI Committee on Public Affairs, 2005-2012
His primary areas of investigation include Immunology, Neonatal Fc receptor, Immunoglobulin G, MHC class I and Molecular biology. His work investigates the relationship between Immunology and topics such as Cytotoxic T cell that intersect with problems in T cell and NOD mice. His studies deal with areas such as Receptor and In vivo as well as Neonatal Fc receptor.
As part of the same scientific family, he usually focuses on Immunoglobulin G, concentrating on Fc receptor and intersecting with Pemphigus, Pemphigoid, Pemphigus foliaceus, Bullous pemphigoid and Pemphigus vulgaris. His MHC class I research is multidisciplinary, incorporating elements of Transcytosis, Autoimmune disease and Proinflammatory cytokine. His Molecular biology research includes elements of B-cell receptor, B cell, Allele and Resorption.
Derry C. Roopenian focuses on Immunology, Antigen, Molecular biology, Major histocompatibility complex and CD8. The study of Immunology is intertwined with the study of Porphyromonas gingivalis in a number of ways. His Antigen research is multidisciplinary, relying on both Cytotoxic T cell and Antigen presentation.
His research integrates issues of In vitro, Lymphokine, Peptide sequence, Gene and CTL* in his study of Molecular biology. His specific area of interest is Immunoglobulin G, where Derry C. Roopenian studies Neonatal Fc receptor. His research investigates the connection between Neonatal Fc receptor and topics such as Receptor that intersect with issues in Albumin.
His primary areas of study are Immunology, Neonatal Fc receptor, Cell biology, Antibody and Immunoglobulin G. His research ties Cytotoxic T cell and Immunology together. His Neonatal Fc receptor study integrates concerns from other disciplines, such as Retina, Albumin, Pharmacology, Transcytosis and Monoclonal antibody.
Derry C. Roopenian has included themes like Plasma cell, Recombinant antibodies, Antigen and Pathology in his Cell biology study. His Antibody research is multidisciplinary, incorporating perspectives in Carbohydrate metabolism and Major histocompatibility complex. Derry C. Roopenian works mostly in the field of Major histocompatibility complex, limiting it down to topics relating to Human leukocyte antigen and, in certain cases, Antigen presentation and Molecular biology.
Derry C. Roopenian spends much of his time researching Immunology, Immunoglobulin G, Neonatal Fc receptor, Antibody and Monoclonal antibody. As part of his studies on Immunology, Derry C. Roopenian often connects relevant areas like Systemic lupus erythematosus. His Immunoglobulin G research incorporates elements of Germinal center, Spleen, Microarray, Angioimmunoblastic T-cell lymphoma and Cell biology.
His Antibody research integrates issues from Major histocompatibility complex, Immune system and Immunity. His research investigates the connection between Monoclonal antibody and topics such as Receptor that intersect with problems in Albumin. Derry C. Roopenian interconnects MHC class I, Antigen, MHC class II and Antigen-presenting cell in the investigation of issues within Antigen presentation.
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FcRn: the neonatal Fc receptor comes of age
Derry C. Roopenian;Shreeram Akilesh.
Nature Reviews Immunology (2007)
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
Katsutoshi Ozaki;Katsutoshi Ozaki;Rosanne Spolski;Rachel Ettinger;Hyoung Fyo Kim.
Journal of Immunology (2004)
The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan.
Chaity Chaudhury;Samina Mehnaz;John M. Robinson;William L. Hayton.
Journal of Experimental Medicine (2003)
Enhanced antibody half-life improves in vivo activity
Jonathan Zalevsky;Aaron K Chamberlain;Holly M Horton;Sher Karki.
Nature Biotechnology (2010)
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
Stefka B. Petkova;Shreeram Akilesh;Thomas J. Sproule;Gregory J. Christianson.
International Immunology (2006)
Human Neonatal Fc Receptor Mediates Transport of IgG into Luminal Secretions for Delivery of Antigens to Mucosal Dendritic Cells
Masaru Yoshida;Steven M Claypool;Jessica S Wagner;Emiko Mizoguchi.
Immunity (2004)
The MHC Class I-Like IgG Receptor Controls Perinatal IgG Transport, IgG Homeostasis, and Fate of IgG-Fc-Coupled Drugs
Derry C. Roopenian;Gregory J. Christianson;Thomas J. Sproule;Aaron C. Brown.
Journal of Immunology (2003)
CD4+ T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice
P J Baker;M Dixon;R T Evans;L Dufour.
Infection and Immunity (1999)
Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant
David V Serreze;Edward H Leiter;Gregory J Christianson;Dale Greiner.
Diabetes (1994)
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice.
Jason A. Bubier;Thomas J. Sproule;Oded Foreman;Rosanne Spolski.
Proceedings of the National Academy of Sciences of the United States of America (2009)
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