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John R. Desjarlais

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
13892
World Ranking
8777
National Ranking
3926

John R. Desjarlais publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John R. Desjarlais sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 247 publications — 66th percentile

66% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John R. Desjarlais D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John R. Desjarlais sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 66 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John R. Desjarlais is affiliated with Pennsylvania State University in the United States. Their research predominantly spans the fields of Medicine and Immunology and Microbiology, with notable work in Immunology, Radiology, Nuclear Medicine and Imaging, Oncology, Molecular Biology, and Biotechnology.

They have focused extensively on topics such as Monoclonal and Polyclonal Antibodies Research, CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Cancer Immunotherapy and Biomarkers, Glycosylation and Glycoproteins Research, and Advanced Biosensing Techniques and Applications.

Desjarlais has contributed to various scientific journals and conference proceedings. Frequent publication venues include:

  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • European Journal of Pharmaceutical Sciences
  • JCI Insight
  • Journal of Clinical Oncology

Among their recent papers are:

  • Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022, 2021, JCI Insight
  • Complex PK-PD of an engineered IL-15/IL-15Rα-Fc fusion protein in cynomolgus monkeys: QSP modeling of lymphocyte dynamics, 2023, European Journal of Pharmaceutical Sciences
  • Preliminary safety and pharmacodynamic (PD) activity of XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in a phase I dose escalation study of patients with selected advanced solid tumors., 2020, Journal of Clinical Oncology
  • Abstract 2286: XmAb30819, an XmAb®2+1 ENPP3 x CD3 bispecific antibody for RCC, demonstrates safety and efficacy in in vivo preclinical studies, 2020, Cancer Research
  • Abstract 1860: Bispecific claudin-6 x CD3 antibodies in a 2 + 1 format demonstrate selectivity and activity on human ovarian cancer cells, 2021, Cancer Research

The scientist has collaborated frequently with colleagues including Rumana Rashid, Christine Bonzon, Kendra N. Avery, Matthew J. Bernett, and Umesh S. Muchhal, reflecting a network of collaborative research engagement.

Best Publications

  • OPTIMIZED Fc VARIANTS AND METHODS FOR THEIR GENERATION

    Gregory Alan Lazar;Arthur J. Chirino;Wei Dang;John Rudolph Desjarlais

  • Enhanced antibody half-life improves in vivo activity

    Jonathan Zalevsky;Aaron K Chamberlain;Holly M Horton;Sher Karki

  • Optimized Fc Variants

    Gregory Alan Lazar;Wei Dang;John R. Desjarlais;Sher Bahadur Karki

  • De novo design of the hydrophobic cores of proteins.

    John R. Desjarlais;Tracy M. Handel

  • Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells

    John O. Richards;Sher Karki;Greg A. Lazar;Hsing Chen

  • Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia

    Holly M. Horton;Matthew J. Bernett;Erik Pong;Matthias Peipp

  • FC variants with altered binding to FCRN

    Aaron Keith Chamberlain;John R. Desjarlais;Sher Bahadur Karki;Greogory Alan Lazar

  • Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins.

    John R. Desjarlais;Jeremy M. Berg

  • Toward rules relating zinc finger protein sequences and DNA binding site preferences.

    John R. Desjarlais;Jeremy M. Berg

  • Inactivation of TNF signaling by rationally designed dominant-negative TNF variants.

    Paul M. Steed;Malu G. Tansey;Jonathan Zalevsky;Eugene A. Zhukovsky

  • Fc VARIANTS WITH OPTIMIZED PROPERTIES

    Gregory Alan Lazar;Wei Dang;John R. Desjarlais;Sher Bahadur Karki

  • Rational design and engineering of therapeutic proteins.

    Shannon A. Marshall;Greg A. Lazar;Arthur J. Chirino;John R. Desjarlais

  • De novo design of the hydrophobic core of ubiquitin.

    Greg A. Lazar;John R. Desjarlais;Tracy M. Handel

  • Optimizing engagement of the immune system by anti-tumor antibodies: an engineer's perspective.

    John R. Desjarlais;Greg A. Lazar;Eugene A. Zhukovsky;Seung Y. Chu

  • Fc Variants With Optimized Fc Receptor Binding Properties

    John R. Desjarlais;Sher Bahadur Karki;Gregory Alan Lazar;John Owen Richards

  • Protein design automation for protein libraries

    Joerg Bentzien;Bassil I. Dahiyat;John Desjarlais;Robert J. Hayes

  • Side-chain and backbone flexibility in protein core design.

    John R. Desjarlais;Tracy M. Handel

  • Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcγRIIb with Fc-engineered antibodies

    Seung Y. Chu;Igor Vostiar;Sher Karki;Gregory L. Moore

  • A molecular immunology approach to antibody humanization and functional optimization.

    Greg A. Lazar;John R. Desjarlais;Jonathan Jacinto;Sher Karki

  • From coiled coils to small globular proteins: Design of a native-like three-helix bundle

    James W. Bryson;John R. Desjarlais;John R. Desjarlais;Tracy M. Handel;William F. Degrado

Frequent Co-Authors

Matthias Peipp
Matthias Peipp Kiel University
Malú G. Tansey
Malú G. Tansey University of Florida
Tracy M. Handel
Tracy M. Handel University of Montana
Nikhil C. Munshi
Nikhil C. Munshi Harvard University
Stephen L. Mayo
Stephen L. Mayo California Institute of Technology
Yu-Tzu Tai
Yu-Tzu Tai Harvard University
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
William Stohl
William Stohl University of Southern California
Thomas Valerius
Thomas Valerius Kiel University
Paul G. Richardson
Paul G. Richardson Harvard University

External Links

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Best Scientists Citing John R. Desjarlais

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William F. DeGrado

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Publications: 30

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Christian Klein

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Publications: 29

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Publications: 29

Herren Wu

Herren Wu

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Publications: 29

Paul W. H. I. Parren

Paul W. H. I. Parren

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Publications: 28

David Baker

David Baker

University of Washington

Publications: 28

Stephen L. Mayo

Stephen L. Mayo

California Institute of Technology

Publications: 27

Tanja Kortemme

Tanja Kortemme

University of California, San Francisco

Publications: 27

Inger Sandlie

Inger Sandlie

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Publications: 27

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Thomas Valerius

Kiel University

Publications: 25

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Jeffrey V. Ravetch

Rockefeller University

Publications: 25

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Jan Terje Andersen

University of Oslo

Publications: 25

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Michel C. Nussenzweig

Rockefeller University

Publications: 24

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Brian Kuhlman

University of North Carolina at Chapel Hill

Publications: 23

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Chi-Huey Wong

Scripps Research Institute

Publications: 20

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