What is he best known for?
The fields of study he is best known for:
- Antibody
- Immune system
- Enzyme
John R. Desjarlais mainly investigates Antibody, Protein design, Computational biology, Antigen and Immunology.
His work carried out in the field of Antibody brings together such families of science as Receptor and Half-life.
His studies deal with areas such as Crystallography, Circular dichroism, Protein engineering and Combinatorial chemistry as well as Protein design.
The concepts of his Computational biology study are interwoven with issues in Epitope and Major histocompatibility complex.
As part of one scientific family, John R. Desjarlais deals mainly with the area of Antigen, narrowing it down to issues related to the Cell biology, and often Cell.
His Immunology research is multidisciplinary, relying on both Pharmacology, Dosing and In vivo.
His most cited work include:
- OPTIMIZED Fc VARIANTS AND METHODS FOR THEIR GENERATION (674 citations)
- Optimized Fc Variants (541 citations)
- Enhanced antibody half-life improves in vivo activity (460 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Antibody, Immunology, Computational biology, Biochemistry and Molecular biology.
John R. Desjarlais combines subjects such as Cancer research, Antigen and Effector with his study of Antibody.
His studies in Cancer research integrate themes in fields like T cell, Receptor, Blockade, In vivo and CD20.
His Immunology and Immunoglobulin E and Immunotherapy investigations all form part of his Immunology research activities.
His Computational biology study integrates concerns from other disciplines, such as Protein engineering and Protein design.
His study in Protein design is interdisciplinary in nature, drawing from both Crystallography, Circular dichroism and Combinatorial chemistry.
He most often published in these fields:
- Antibody (43.60%)
- Immunology (15.64%)
- Computational biology (15.17%)
What were the highlights of his more recent work (between 2013-2021)?
- Antibody (43.60%)
- T cell (8.06%)
- Antigen (12.32%)
In recent papers he was focusing on the following fields of study:
John R. Desjarlais mostly deals with Antibody, T cell, Antigen, Cancer research and CD3.
His Antibody study deals with the bigger picture of Immunology.
His research integrates issues of Receptor, Cytokine and In vivo in his study of T cell.
John R. Desjarlais has included themes like Single-Chain Fv, Immunity and Fc domain in his Antigen study.
He interconnects Cancer, Prostate cancer, Cell culture, Blockade and Fusion protein in the investigation of issues within Cancer research.
His CD3 study combines topics in areas such as Cancer cell and T-cell receptor.
Between 2013 and 2021, his most popular works were:
- Novel heterodimeric proteins (69 citations)
- Bispecific antibodies that bind to CD38 and CD3 (47 citations)
- Heterodimeric antibodies that bind cd3 and tumor antigens (43 citations)
In his most recent research, the most cited papers focused on:
- Antibody
- Immune system
- Enzyme
The scientist’s investigation covers issues in Antibody, Antigen, Immunology, Biochemistry and CD3.
His Antibody research incorporates themes from Nucleic acid, Stereochemistry and Virology.
He has researched Nucleic acid in several fields, including Combinatorial chemistry and Computational biology.
His work in Antigen addresses issues such as T cell, which are connected to fields such as Cancer cell, Cytokine, Multiple myeloma and Cancer research.
His CD3 research is multidisciplinary, incorporating perspectives in Cell killing, Potency, Pharmacology and T-cell receptor.
His work in Immunotherapy addresses subjects such as Epidermal growth factor receptor, which are connected to disciplines such as In vivo.
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