World's Best Scientists 2026 revealed!
Matthias Peipp

Matthias Peipp

D-Index & Metrics

Immunology

D-Index
46
Citations
8940
World Ranking
4604
National Ranking
304

Overview

Matthias Peipp is affiliated with Kiel University in Germany and has a research focus primarily in the fields of Medicine and Immunology and Microbiology. Their work spans a range of subfields including Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, and Genetics.

The main topics covered by Matthias Peipp's research include:

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Immune Cell Function and Interaction
  • Acute Lymphoblastic Leukemia research
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Phagocytosis and Immune Regulation

The scientist has frequently published in the following venues:

  • Frontiers in Immunology
  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Klinische Pädiatrie
  • Neuro-Oncology

Among the recent noteworthy publications are:

  • CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity (2021, Leukemia)
  • Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement (2020, The Journal of Immunology)
  • Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL (2022, Blood)
  • Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages (2022, Frontiers in Immunology)
  • Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells (2023, Frontiers in Immunology)

Matthias Peipp collaborates extensively with a number of researchers. Frequent co-authors include Katja Klausz, Dorothee Winterberg, Christian Kellner, Steffen Krohn, and Thomas Valerius.

Best Publications

  • Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors

    Michel De Weers;Yu Tzu Tai;Michael S. Van Der Veer;Joost M. Bakker

  • T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

    Priti Kumar;Hong Seok Ban;Sang Soo Kim;Haoquan Wu

  • Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia

    Holly M. Horton;Matthew J. Bernett;Erik Pong;Matthias Peipp

  • Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor.

    Heike Hofmann;Martina Geier;Andrea Marzi;Mandy Krumbiegel

  • Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

    Tanja Schneider-Merck;Jeroen J. Lammerts van Bueren;Sven Berger;Kai Rossen

  • Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells.

    Matthias Peipp;Jeroen J. Lammerts van Bueren;Tanja Schneider-Merck;Wim W. K. Bleeker

  • Complement-dependent tumor cell lysis triggered by combinations of epidermal growth factor receptor antibodies.

    Michael Dechant;Wencke Weisner;Sven Berger;Matthias Peipp

  • Novel Bispecific Antibodies Increase γδ T-Cell Cytotoxicity against Pancreatic Cancer Cells

    Hans-Heinrich Oberg;Matthias Peipp;Christian Kellner;Susanne Sebens

  • Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7

    Edwin Bremer;Douwe F. Samplonius;Matthias Peipp;Linda van Genne

  • IgA EGFR antibodies mediate tumour killing in vivo

    Peter Boross;Stefan Lohse;Maaike Nederend;Johannes Hendrik Marco Jansen

  • Bispecific antibodies targeting cancer cells.

    Matthias Peipp;Thomas Valerius

  • Effector Mechanisms of Recombinant IgA Antibodies against Epidermal Growth Factor Receptor

    Michael Dechant;Thomas Beyer;Tanja Schneider-Merck;Wencke Weisner

  • FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils

    Louise W. Treffers;Michel van Houdt;Christine W. Bruggeman;Marieke H. Heineke

  • Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

    Christian Kellner;Anna Otte;Elisa Cappuzzello;Katja Klausz

  • Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies

    Holly M. Horton;Matthew J. Bernett;Matthias Peipp;Erik Pong

  • A Recombinant CD7-specific Single-Chain Immunotoxin Is a Potent Inducer of Apoptosis in Acute Leukemic T Cells

    Matthias Peipp;Heide Küpers;Domenica Saul;Beate Schlierf

  • A novel CD19-directed recombinant bispecific antibody derivative with enhanced immune effector functions for human leukemic cells.

    Christian Kellner;Joerg Bruenke;Julia Stieglmaier;Michael Schwemmlein

  • Tribody [(HER2)2xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells.

    Hans H. Oberg;Christian Kellner;Daniel Gonnermann;Susanne Sebens

  • Effective lysis of lymphoma cells with a stabilised bispecific single-chain Fv antibody against CD19 and FcgammaRIII (CD16).

    Joerg Bruenke;Karin Barbin;Susanne Kunert;Peter Lang

  • Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC

    Roland Repp;Christian Kellner;Anja Muskulus;Matthias Staudinger

  • Boosting ADCC and CDC activity by Fc engineering and evaluation of antibody effector functions.

    Christian Kellner;Stefanie Derer;Thomas Valerius;Matthias Peipp

  • The antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra- and intermolecular flexibility

    Jeroen J. Lammerts van Bueren;Wim K. Bleeker;Annika Brännström;Anne von Euler

Frequent Co-Authors

Thomas Valerius
Thomas Valerius Kiel University
Jan G. J. van de Winkel
Jan G. J. van de Winkel Genmab (United States)
Paul W. H. I. Parren
Paul W. H. I. Parren Leiden University Medical Center
Dieter Kabelitz
Dieter Kabelitz Kiel University
Daniela Wesch
Daniela Wesch Kiel University
Georg H. Fey
Georg H. Fey University of Erlangen-Nuremberg
Jeanette H. W. Leusen
Jeanette H. W. Leusen Utrecht University
Martin Schrappe
Martin Schrappe Kiel University
John R. Desjarlais
John R. Desjarlais Pennsylvania State University
Falk Nimmerjahn
Falk Nimmerjahn University of Erlangen-Nuremberg

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, exploring related fields like nursing can open diverse career opportunities. Many professionals pursue advanced qualifications to enhance their expertise and increase earning potential. Understanding the doctorate in nursing salary across states can help in making informed decisions about educational investments.

Transitioning roles within nursing specialties is common. For example, moving from a Family Nurse Practitioner to acute care requires specialized training. Resources on acute care nurse practitioner programs offer valuable guidance on this pathway.

Accelerated programs also provide excellent pathways for those ready to advance quickly. Prospective students may find accelerated fnp programs useful for expediting their training in family nursing practice.

For individuals without a nursing background, structured options like 12-month accelerated nursing programs online for non nurses facilitate entry into the nursing profession, offering a swift route to licensure and advanced practice roles. These pathways complement an immunology foundation, broadening career horizons.

Best Scientists Citing Matthias Peipp

Trending Scientists

Recently Published Articles