World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
81
Citations
25716
World Ranking
1089
National Ranking
31

Overview

Nan Shen is affiliated with Shanghai Jiao Tong University in China and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields, including Molecular Biology, Immunology, Epidemiology, Infectious Diseases, and Pediatrics, Perinatology, and Child Health.

The scientist's recent publications cover a range of topics related to genetic metabolic disorders, immune responses, infectious diseases, and respiratory infections. Notable papers include:

  • The Genetic Landscape and Epidemiology of Phenylketonuria (2020) published in The American Journal of Human Genetics
  • Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary T-Helper Cell Type 17 Response that Mitigates Susceptibility to Streptococcus pneumoniae (2020) published in American Journal of Respiratory and Critical Care Medicine
  • Impact of viral coinfection and macrolide-resistant mycoplasma infection in children with refractory Mycoplasma pneumoniae pneumonia (2020) published in BMC Infectious Diseases
  • Structural insights into the recognition of histone H3Q5 serotonylation by WDR5 (2021) published in Science Advances
  • Enhanced genome editing to ameliorate a genetic metabolic liver disease through co-delivery of adeno-associated virus receptor (2020) published in Science China Life Sciences

Nan Shen's research addresses a variety of main topics, including:

  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Immune Cell Function and Interaction
  • Metabolism and Genetic Disorders
  • T-cell and B-cell Immunology
  • Pneumonia and Respiratory Infections
  • Respiratory viral infections research

Frequent coauthors in Nan Shen's work include:

  • Yue Tao
  • Qing Cao
  • Xi Mo
  • Lijuan Luo

Naturally, the publications have appeared multiple times in various scientific venues. Frequent publication venues for the scientist include:

  • PubMed
  • Translational Pediatrics
  • International Journal of Biological Macromolecules
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)

Best Publications

  • The microbiome in early life: implications for health outcomes

    Sabrina Tamburini;Nan Shen;Han Chih Wu;Jose C Clemente

  • Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

    Maria G Dominguez-Bello;Maria G Dominguez-Bello;Kassandra M De Jesus-Laboy;Nan Shen;Laura M Cox

  • The microbiome of uncontacted Amerindians

    Jose C. Clemente;Erica C. Pehrsson;Martin J. Blaser;Martin J. Blaser;Kuldip Sandhu

  • MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins.

    Yuanjia Tang;Xiaobing Luo;Huijuan Cui;Xuming Ni

  • Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity.

    Chu-Xiao Liu;Xiang Li;Fang Nan;Shan Jiang

  • Targeting interleukin-6 in inflammatory autoimmune diseases and cancers.

    Xin Yao;Jiaqi Huang;Haihong Zhong;Nan Shen

  • TLR7 gain-of-function genetic variation causes human lupus

    Unknown

  • Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype.

    Leopoldo N. Segal;Jose C. Clemente;Jun Chieh J. Tsay;Sergei B. Koralov

  • MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

    Wen Pan;Shu Zhu;Min Yuan;Huijuan Cui

  • Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.

    Jing He;Xia Zhang;Yunbo Wei;Xiaolin Sun

  • The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

    Shu Zhu;Wen Pan;Xinyang Song;Yan Liu

  • Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

    Wanling Yang;Nan Shen;Dong-Qing Ye;Qiji Liu;Qiji Liu

  • Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer.

    Jun Chieh J. Tsay;Benjamin G. Wu;Michelle H. Badri;Jose C. Clemente

  • Early-life gut microbiome composition and milk allergy resolution

    Supinda Bunyavanich;Nan Shen;Alexander Grishin;Robert Wood

  • Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray

    Han Gm;Chen Sl;Shen N;Ye S

  • Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus.

    B P Tsao;R M Cantor;K C Kalunian;C J Chen

  • miR-155 and Its Star-Form Partner miR-155* Cooperatively Regulate Type I Interferon Production by Human Plasmacytoid Dendritic Cells

    Haibo Zhou;Xinfang Huang;Huijuan Cui;Xiaobing Luo

  • Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.

    Yin Yao;Yin Yao;Yin Yao;Zhian Chen;Zhian Chen;Hao Zhang;Hao Zhang;Cailing Chen

  • The Genetic Landscape and Epidemiology of Phenylketonuria

    Alicia Hillert;Yair Anikster;Amaya Belanger-Quintana;Alberto Burlina

  • Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

    Nan Shen;Qiong Fu;Qiong Fu;Yun Deng;Yun Deng;Xiaoxia Qian

  • A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

    Xiaobing Luo;Wanling Yang;Dong-Qing Ye;Huijuan Cui

  • Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

    Mar Gacias;Sevasti Gaspari;Patricia-Mae G Santos;Sabrina Tamburini

  • MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus.

    Xia Zhao;Yuanjia Tang;Bo Qu;Huijuan Cui

Frequent Co-Authors

John B. Harley
John B. Harley United States Department of Veterans Affairs
Betty P. Tsao
Betty P. Tsao University of California, Los Angeles
Sang-Cheol Bae
Sang-Cheol Bae Hanyang University
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Swapan K. Nath
Swapan K. Nath Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Timothy J. Vyse
Timothy J. Vyse King's College London

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